Profils multidimensionnels de jeunes enfants trisomiques bulgares

This study examines links between cognitive, communicative, socioemotional and psychomotor abilities in 20 Bulgarian institutionalised children with Down syndrome. These children were evaluated by means of the Early Cognitive Development Assessment Scales (ECDAS, Nader-Grosbois, 1993), the Early Social Communication Scales (ECSP, Guidetti and Tourrette, 1993), and two grids of socioemotional and psychomotor indicators, inspired by the Trandisciplinary Play-Based Assessment (TPBA, Linder, 1990). Several analyses of developmental patterns were performed in order to identify specificities in the structural organisation of abilities in Bulgarian Down syndrome children in situation of abandonment or negligence: comparison of means of scores in distinct domains, correlations, clusters of variables, analysis of individual profiles by clusters of cases. The results indicate: weakness in vocal imitation and in joint attention; limited relationships between communicative abilities; local homologies between some cognitive and communicative abilities implicating a lack of integration; particular links between specific dimensions of socioemotional and psychomotor adaptation and certain cognitive and communicative abilities in these Down syndrome children.     

Theory-Driven Interventions in Psychoneuroimmunology and HIV-1 Infection

Psychoneuroimmunology (PNI) is a rapidly evolving multidisciplinary field founded on the premise that psychosocial factors, the central nervous system, and the immune system are intimately linked. Following publication of scientific evidence supporting this link, a number of animal and human studies have been published, both inside and outside the area of human immunodeficiency virus (HIV) infection and acquired immunodeficiency syndrome. These studies support the existence of bidirectional feedback mechanisms operating between the brain and the immune system. To date, however, there is no all-encompassing model that predicts individual differences in the relationship among psychosocial factors, immunologic measures, and clinical disease progression in HIV type 1 (HIV-1) infection. This variability in human response has been explained by a number of cofactors (host as well as environmental) that appear to accelerate the course of the disease. Since psychosocial factors are highly amenable to behavioral interventions, several models for intervention research have been proposed to evaluate whether such interventions can enhance immune functioning, thereby curtailing disease progression. Examination of these interventions in the context of PNI and HIV-1 infection, however, is rather limited. Therefore, researchers and clinicians must not only consider conceptualizations and paradigms in this area of research, but also focus on empirically testable, theory-driven models that allow for the unique characteristics of individual patients.     

Target-size influences on reaction time with movement time controlled

The variable that affect motor programming time may be studied by changing the nature of the response and measuring the subsequent changes in reaction time (RT). One notion of motor programming suggests that aiming responses with reduced target size and/or increased target amplitude require more "complex" motor programs that require longer RTs. In a series of five experiments which movement time (MT) was experimentally varied target size neither influences RT when the movement amplitude was 2 or 30 cm nor when the target sizes differed by as much as a factor of 16:1. Increasing the movement amplitude from 15 to 30 cm also had no influence on RT. Movement time, however, did affect RT, with 200-msec movements having longer RTs than 120-msec movements. Target size and movement amplitude did not appear to be factors that influence programming time or program complexity.     

Distance judgments under different size-information conditions

Seventy-two Ss judged the absolute distance of a target presented without distance cues other than retinal size and assumed size. The method by which E communicated information about the size of a 3-in. target had a significant effect on the magnitude of the discrepancy between judged distance and the perceived distance required by the size-distance invariance hypothesis. In order of increasing effectiveness in producing distance judgments meeting invariance requirements were: size information in the form of verbally communicated metric units, size information communicated by labeling the target with the name of a familiar object, and size information in the form of a visual representation.