Aggressive behavior inhibition by serotonin and quipazine injected into the amygdala in the rat

The effects on aggressive behavior, open-field activity, and pain threshold of bilateral microinjections of serotonin (20 micrograms) and quipazine (20 micrograms), the direct serotonergic receptor agonist, into the cortico-medial amygdala were investigated in Wistar rats. Both drugs significantly prolonged the attack latency in isolated killer rats (predatory aggression model), and suppressed the incidence of aggressive postures/attacks in shock-induced fighting test (affective aggression). The only difference in the open-field behavior was the lower number of central square entries in drug-treated compared to saline-injected rats. None of the substances produced any significant change in jump threshold. It is concluded that stimulation of serotonin receptors within the amygdala produces inhibition of affective and muricidal behavior in isolated rats. The effect does not seem to be dependent on changes in general activity and pain sensitivity.     

Frequency of neurologic-psychiatric findings in the late phase following minor and medium severe blunt craniocerebral injuries

The authors present a short review of the pertinent literature and report on their own neuropsychiatric findings following internal craniocerebral injuries, at the same time drawing attention to the necessity of psychological examination. Statistical comparisons with the international literature are complicated owing to the different classifications used for craniocerebral injuries.     

The Hispanic Treatment Program: Principles of effective psychotherapy

The Hispanic Treatment Program was an inpatient psychotherapy Unit at the Colorado State Hospital that operated from October 1979 to February 1982. Staffed exclusively with personnel of Hispanic heritage, the Program emphasized the use of linguistic and cultural elements, as well as the customs and beliefs characteristic of Hispanic culture. A specialized inpatient treatment unit for Hispanic patients with psychotic (especially, schizophrenia) disturbances, the Program offered a unique opportunity to these patients by providing a variety of psychotherapies conducted in a culturally-sensitive manner. Spanish and English were used in a manner conducive to enhancing the treatment process, with flexibility in use of language.This project was supported by Grant No. ROlMH29016-01A2, awarded by the National Institute of Mental Health, Center for Minority Group Mental Health.The authors acknowledge Gregorio Kort, M.D. and Wayne Smyer, M.A. and other staff for their contributions to the development and success of the Hispanic Treatment Program.Original version of paper was selected for the First Senior Award given by the Psychological Services Center's (NYSCP) Minority Mental Health Award Competition.     

Predicting child behavior problems in maritally violent families

Previous research indicates that children from violent marriages are more likely to suffer from conduct problems and/or anxiety disorders than children from nonviolent, satisfactory marriages. However, knowledge regarding specific factors present in violent marriages relating to child problems is limited. The present study examined the relationships involving interspousal aggression, parent-child aggression, and child behavior problems in a sample of 45 children from maritally violent families. Mothers indicated how often their children witnessed interspousal aggression and were victims of parent-child aggression. Mothers also rated their children's problem behaviors while children reported on their own depressive symptoms. The witnessing of interspousal aggression was highly associated with parental aggression directed toward children. Parent-child aggression related to attention problems, anxiety-withdrawl, motor excess, and conduct problems in children. However, the witnessing of interspousal aggression was not significantly related to child behavior problems. These results are consistent with theoretical predictions linking marital problems to child behavior by virtue of their association with parenting.This research was supported in part by a Grant-in-Aid of Research awarded to the first author by Sigma Xi, the Scientific Research Society, and NIMH Grant No. MH35340 awarded to the third author. The authors wish to thank Martha Wray and her staff at VIBS for their help throughout this project.