Psychopathy screening of incarcerated juveniles: a comparison of measures

How well do brief screening measures correspond with a full-scale assessment of psychopathy among juvenile offenders? This study compared 3 independent screening measures (the Antisocial Process Screening Device [APSD] Self-Report [A. A. Caputo, P. J. Frick, & S. L. Brodsky, 1999], the APSD Staff Rating [P. J. Frick & R. D. Hare, 2001], and the Psychopathy Content Scale [D. C. Murrie & D. G. Cornell, 2000] on the Millon Adolescent Clinical Inventory [T. Millon, 1993]) with the Psychopathy Checklist: Youth Version (PCL:YV; A. E. Forth, D. S. Kosson, & R. D. Hare, in press) in a sample of 117 incarcerated male juveniles. Modest correlations (.30-.49) were found between PCL:YV scores and those of the 3 screening measures, and there was moderate accuracy (67%-82%) in identifying youth who scored relatively high (> or = 25) on the PCL:YV. Although these results support the construct of adolescent psychopathy, they indicate substantial limitations in the use of psychopathy screening measures with juvenile offenders.     

Evidence for preserved representations in change blindness

People often fail to detect large changes to scenes, provided that the changes occur during a visual disruption. This phenomenon, known as "change blindness," occurs both in the laboratory and in real-world situations in which changes occur unexpectedly. The pervasiveness of the inability to detect changes is consistent with the theoretical notion that we internally represent relatively little information from our visual world from one glance at a scene to the next. However, evidence for change blindness does not necessarily imply the absence of such a representation---people could also miss changes if they fail to compare an existing representation of the pre-change scene to the post-change scene. In three experiments, we show that people often do have a representation of some aspects of the pre-change scene even when they fail to report the change. And, in fact, they appear to "discover" this memory and can explicitly report details of a changed object in response to probing questions. The results of these real-world change detection studies are discussed in the context of broader claims about change blindness.     

Extending the ALCOVE model of category learning to featural stimulus domains

The ALCOVE model of category learning, despite its considerable success in accounting for human performance across a wide range of empirical tasks, is limited by its reliance on spatial stimulus representations. Some stimulus domains are better suited to featural representation, characterizing stimuli in terms of the presence or absence of discrete features, rather than as points in a multidimensional space. We report on empirical data measuring human categorization performance across a featural stimulus domain and show that ALCOVE is unable to capture fundamental qualitative aspects of this performance. In response, a featural version of the ALCOVE model is developed, replacing the spatial stimulus representations that are usually generated by multidimensional scaling with featural representations generated by additive clustering. We demonstrate that this featural version of ALCOVE is able to capture human performance where the spatial model failed, explaining the difference in terms of the contrasting representational assumptions made by the two approaches. Finally, we discuss ways in which the ALCOVE categorization model might be extended further to use “hybrid” representational structures combining spatial and featural components.     

Cholinesterase-inhibitor therapy for dementia: novel clinical substrates and mechanisms for treatment response

Historically, drugs that increase central cholinergic transmission have primarily been investigated for relieving cognitive symptoms in mild-to-moderate Alzheimer's disease. These efforts have led to the somewhat unexpected findings that cholinergic therapy has a beneficial effect on selected neuropsychiatric symptoms in AD across disease stages. In Parkinson's disease with dementia and dementia with Lewy bodies, cholinergic deficits are more severe than in AD, and there is emerging evidence that cholinesterase inhibitors are efficacious in treating core symptoms of attentional disturbance and psychosis. Recent data also suggest a rational basis for cholinergic therapy in vascular dementia. The cognitive and neuropsychiatric effects of cholinergic therapy observed in AD and other dementias form the crux of an integrative model of cholinergic therapeutic efficacy that encompasses the diverse central nervous system actions of acetylcholine and its complementary interactions with central monoamine transmitters. This heuristic framework highlights the broader therapeutic potential of cholinergic therapy for symptom-based indications in other neuropsychiatric disorders.     

Notes on Contributors

Biography

Notes on Contributors     

Touching Mortality, Touching Strength: Clinical Work with Dying Patients

This paper outlines some of the special stresses that must be shouldered by clinicians—physicians, nurses, chaplains, social workers, pastoral staff, and others—whose work focuses on dying and extremely vulnerable patients. The utility of a theory of generative death anxiety as a framework for interpreting the nature of these special stresses is suggested. Three common burnout reactions are examined. The paper concludes that positive acceptance of personal mortality may help clinicians avoid burnout and lead to better therapeutic practice. This framework for interpreting therapeutic practice demonstrates the integral role spirituality plays in work with this particular patient group.     

Implicit motor sequence learning is represented in response locations

Previous work (Willingham, 1999) has indicated that implicit motor sequence learning is not primarily perceptual; that is, what is learned is not a sequence of stimuli. Still other work has indicated that implicit motor sequence learning is not specific to particular muscle groups or effectors. In the present work, we tested whether implicit motor sequence learning would be represented as a sequence of response locations. In Experiment 1, learning showed very poor transfer when the response locations were changed, even though the stimulus positions were unchanged. In Experiment 2, participants switched their hand positions at transfer, so that one group of participants pushed the same sequence of keys but used a different sequence of finger movements to do so, whereas another group pushed a different sequence of keys but used the same sequence of finger movements used at training. Knowledge of the sequence was shown at transfer only if the sequence of response locations was maintained, not the sequence of finger movements.     

From case management to prevention of scientific dishonesty in Denmark

In 1992, The Danish Medical Research Council established a national committee on scientific dishonesty with the twofold task of handling cases of scientific misconduct and taking preventive initiatives. Scientific dishonesty was proven in only five cases, but in another nine cases lesser degrees of deviations from good scientific practice were found. The experiences from a total of 24 treated cases indicated that three key areas were at the basis of most of the accusations and the deviations from good practice: uncertainty about 1) authorship, about 2) rights and duties to use scientific data and about 3) agreements at the initiation of joint studies. As a consequence guidelines on good practice have been issued on these key subjects. An earlier version of this paper was presented at a symposium, Scientific Misconduct. An International Perspective, organised by The Medical University of Warsaw, 16 November, 1998.