Competing interests: The need to control conflict of interests in biomedical research

Individual and institutional conflict of interests in biomedical research have becomes matters of increasing concern in recent years. In the United States, the growth in relationships — sponsored research agreements, consultancies, memberships on boards, licensing agreements, and equity ownership — between for-profit corporations and research universities and their scientists has made the problem of conflicts, particularly financial conflicts, more acute. Conflicts can interfere with or compromise important principles and obligations of researchers and their institutions, e.g., adherence to accepted research norms, duty of care to patients, and open exchange of information. Disclosure is a key component of a successful conflict policy. Commitments which conflict with a faculty member's primary obligations to teaching, research, administrative responsibilities, or patient care also need attention. Institutional conflict of interests present different problems, some of which are discussed in an analysis of an actual problem posed by two proposed clinical trials. This paper is adapted from a lecture presented to a Symposium on Scientific Integrity, Warsaw, Poland, 23 November 1995. Daniel Steiner was Vice-President and General Counsel of Harvard University (1972–92) and in that capacity became familiar with conflict of interest issues. He is currently Counsel to the Boston law firm. Ropes and Gray, and is Adjunct Lecturer in Public Policy at the John F. Kennedy School of Government. Harvard University.     

The “good manager”: Sex-typed,androgynous, or likable?

Recent studies have indicated that people describe a “good manager” in masculine terms. It was hypothesized that this could simply reflect cultural stereotypes, rather than people's perceptions of what combination of traits is desirable in a leader. In Experiments 1 and 2, subjects were presented managerial profiles ascribing all masculine, all feminine, or a combination of masculine and feminine traits (i.e., “androgynous” profiles) to hypothetical managers. Feminine-trait combinations were rated as significantly less desirable than either masculine or androgynous combinations, which were rated as equally desirable. Thus, while femininity per se was not seen as desirable in a leader, it was not viewed as a liability when combined with masculinity, a corroboration of much behavioral research on androgyny. Experiment 3 varied trait likableness and sex-role orientation. Experiments 1 and 2 were replicated for unlikable traits. Surprisingly, the opposite pattern was obtained for likable traits: the feminine combinations were rated as the most desirable, and the masculine combinations were rated as the least desirable. The results are discussed in the context of early research on impression formation and recent work on social cognition.     

Who we are: The political origins of the medical humanities

The medical humanities were organized, beginning in the late 1960s, by a small group of people who shared a critique of medical education and a commitment to vigorous action to change it. They proposed to create several demonstration programs in humanities education at American schools. Although the group began with a religious orientation, it soon acquired a broader, more secular mission. As a result of shrewd political organizing, the group attracted members from within medicine, and was awarded a grant to promote the medical humanities. This paper describes these events and sets them in the context of the social and medical history of the 1960s and early 1970s.     

Depth of processing: When the principle of congruity fails

Two factors, level of processing (Craik & Lockhart, 1972) and congruity (Schulman, 1974), known to have large effects on the recall of experimenter-provided responses to questions, were examined in a series of five incidental learning experiments using subject-generated responses. The data show that manipulation of level of processing has the same effect on recall of subjectgenerated responses as it does on experimenter-provided responses. However, the effect of congruity is reversed for subject-generated responses. The data suggest that the difficulty of generating unrelated responses (“incongruous“ items) may account, at least in part, for the failure of the “principle of congruity“ with subject-generated responses.     

SEVERE CLASSROOM BEHAVIOR PROBLEMS: TEACHERS OR COUNSELLORS

This experiment was designed to determine the relative effectiveness of teacher and counselling approaches in the reduction of disruptive or inappropriate classroom behavior. Inappropriate classroom behavior frequencies of 12 academically low achieving, seventh-grade, black male students, with a reported high rate of inappropriate classroom behavior, were recorded. Three groups, with nearly equal mean inappropriate behaviors, were randomly assigned to one of three treatment conditions: behavioral counselling, client-centered counselling, or no counselling. Each counselling group received fifteen 30-minute counselling sessions, at a rate of two to three times a week. In addition to counselling, all students subsequently received teacher approval within the classroom. Results indicated that the teacher was able to reduce inappropriate behavior more than any counselling group. There were also indications that behavioral counselling, but not client-centered counselling, was moderately helpful in reducing inappropriate classroom behavior.     

Counseling for Decisions

This article presents a model for training counselors to help counselees in the process of making decisions. Three ineffective decision strategies (avoidance, excessive caution, and impulse) are explained and illustrated. An effective decision-helping approach that includes processing decisions, relating values to process, and relating actions to beliefs is presented. The authors contend that in order to produce satisfactory and adequate decisions, deeply rooted affective influences as well as logic and information must be dealt with.     

Organizational preparedness for change: Staff acceptance of an on-line computer-assisted assessment system

An on-line assessment system is briefly described. Previous positive evaluation studies are summarized. Results of studies of staff acceptance and staff preparedness for change are reported. Findings are interpreted in terms of the need for planning for change. Implications related to the acceptance of other on-line computer systems in psychology are discussed.     

Developmental trends in distractibility: Is absolute or proportional decrement the appropriate measure of interference?

Since baseline performance varies with age, diminished interference effects found with increasing age do not provide evidence for a developmental trend in distractibility unless their relationship to baseline performance is known. In the present study, baseline difficulty was varied in two speeded classification experiments to investigate whether interference effects due to irrelevant information could best be characterized by absolute or proportional decrement models. In Experiment 1, first graders, third graders, and adults sorted cards on the basis of square size, both in the presence and absence of extraneous stimulus information. In Experiment 2, first graders and adults sorted cards on the basis of the density of a regular array of dots and two kinds of irrelevant information were used. Robust interference effects were found which declined with age. Manipulating discriminability of the relevant stimulus dimension resulted in large changes in sorting time, but interference effects did not vary with baseline difficulty. These results were interpreted as strongly supporting both an absolute decrement model and a developmental trend in distractibility.