疼痛恐惧的神经机制及其消退

疼痛恐惧是疼痛基础和临床研究中的一个重要课题。个体对疼痛信息产生过度警觉,诱发不恰当的回避行为,扰乱机体的正常功能,加剧疼痛的现象即为疼痛恐惧。疼痛恐惧可影响个体的疼痛感知以及疼痛相关的注意和回避行为,且在慢性疼痛(如慢性肌骨骼疼痛)的发展、维持个体正常生理功能的丧失中起着重要作用。疼痛恐惧的形成与表达涉及杏仁核、海马、背侧前扣带回皮层、和前额叶皮层等脑区的参与。当前的疼痛恐惧消退的心理-行为干预方法可在疼痛恐惧加工的不同阶段(巩固、再巩固和消退)消退个体的疼痛恐惧。然而,由于恐惧记忆形成过程较为复杂并受多种因素影响,疼痛恐惧记忆消退方法效果较不稳定,其基础研究与临床应用之间仍存在较大的鸿沟。将来研究有必要考虑到疼痛恐惧形成环境的差异以及个体人格特质/心理状态的差异,逐步完善相关消退方法并将其引入临床镇痛,以期帮助患者弱化、擦除甚至改写困扰他们的疼痛恐惧,从而缓解甚至消除病患的疼痛。     

A defense of intuitions

Radical experimentalists argue that we should give up using intuitions as evidence in philosophy. In this paper, I first argue that the studies presented by the radical experimentalists in fact suggest that some intuitions are reliable. I next consider and reject a different way of handling the radical experimentalists’ challenge, what I call the Argument from Robust Intuitions. I then propose a way of understanding why some intuitions can be unreliable and how intuitions can conflict, and I argue that on this understanding, both moderate experimentalism and the standard philosophical practice of using intuitions as evidence can help resolve these conflicts.

On the generality of the contingent orienting hypothesis

The contingent-orienting hypothesis states that attentional capture by a task-irrelevant stimulus is contingent on whether that stimulus shares a feature property that is critical to the task at hand [Folk, C. L., Remington, R. W., & Johnston, J. C. (1992). Involuntary covert orienting is contingent on attentional control settings. Journal of Experimental Psychology: Human Perception and Performance, 18, 1030-1044]. Studies supporting this hypothesis have mostly used set size four displays throughout the experiment and thus constrict its ecological validity, since conclusions drawn from experiments using fixed set-size displays may not be generalized to other conditions with different set sizes. We used a spatial cueing paradigm in which a non-informative onset or color cue preceded an onset or a color target, and manipulated set size as a within- or between-subject factor. In four experiments, the original finding of Folk et al. (1992) was replicated only when a fixed set size (four) was used throughout. When both set-size four and eight were used in an experiment, stimulus-driven capture by onset in search of a color target was found even for set-size four displays. These results raise doubts as to the generality of the contingent-orienting hypothesis and help to delineate the boundary conditions on this hypothesis.     

Development and initial validation of public domain Basic Interest Markers

Goldberg (Goldberg, L. R. (1999). A broad-bandwidth, public-domain, personality inventory measuring the lower-level facets of several five-factor models. In: I. Mervielde, I. Deary, F. De Fruyt, & F. Ostendorf (Eds.), Personality psychology in Europe (Vol. 7, pp. 7-28). Tilburg, The Netherlands: Tilburg University Press) has argued that the commercialization of personality measures limits the range of questions investigated in empirical research. We propose that the commercialization of interest measures has had a similar effect on research in vocational psychology. Following Goldberg’s example of developing public-domain personality markers, we also propose that the development of public-domain interest markers would facilitate new directions in career-related research. The present study outlines the development and validation of a set of public-domain Basic Interest Markers (BIMs) that are freely available on a website. Using Day and Rounds’ (Day, Susan. X, & Rounds, J. (1997). A little more than kin, and less than kind: Basic interests in vocational research and career counseling. Career Development Quarterly, 45, 207-220) basic interest taxonomy, 343 items and 31 BIM scales were generated. Validity evidence is presented from correlations with the General Occupational Themes and Basic Interest Scales of the Strong Interest Inventory (Harmon, L. W., Hansen, J. C., Borgen, F. H., & Hammer, A. L. (1994). Strong Interest Inventory applications and technical guide. Stanford, CA: Stanford University Press). Discriminant validity is demonstrated by the capacity for the BIMs to differentiate major field of education or training. Implications for research and use in applied settings are discussed.     

高校师德状况调查表的研究

本研究旨在编制一个能够反映我国目前高校教师师德状况的调查表.通过对国内外文献的研究及与专家讨论形成了师德调查表的维度和初始题目.有3所高校的207名教师被抽取,成为预测被试.据此结果保留了48道题.有8个地区10所高校的1092名教师成为再次施测的被试.用该样本数据,确立了调查表的区分度、信度和效度.结果表明,高校师德状况调查表的各项指标皆符合测量学要求,可以作为一个测评工具使用.     

论元代道教戏剧对道教乐生思想的图解

对生命价值的充分肯定和对长生成仙的热烈追求是道教最具特色的教义.元代道教戏剧以独特的视角和艺术的手法对道教乐生思想进行了全方位地形象图解.面对成仙诱惑,凡人的怀疑、拒绝与诘问,正是因为对生的热切渴望对生命的价值强烈认同感使然.情欲乃是人之常情,道教贵生,当然包括对生命基本需求的尊重,对世俗情欲的眷恋与渴望是元代道教戏剧对道教乐生思想的又一诠释.元代道教戏剧着力展现体道之人对山水的乐好,而其乐山好水的审美情趣又与澄心遣欲的宗教追求和隐逸归真的宗教旨意一脉相承.本文以全新的角度阐释元代道教戏剧中体现出的道教乐生思想,以期在加深对道教生命意识的认识的同时,彰显元代道教戏剧独特的艺术价值.     

Treadmill exercise enhances passive avoidance learning in rats: the role of down-regulated serotonin system in the limbic system

While serotonin (5-HT) may impair learning and memory, exercise has been reported to improve them. Whether chronic exercise can facilitate fear memory via regulating the serotonin system is unknown. We examined the effects of 4-week treadmill exercise training on levels of 5-HT and its metabolite 5-hydroxyindoleacetic acid (5-HIAA), the protein expression of its receptor 5-HT_1A and transporter in the amygdala, hippocampus and prefrontal cortex of male Sprague–Dawley rats. Our results demonstrated that treadmill exercise (1) improved the passive avoidance learning performance; (2) decreased the 5-HT level in the hippocampus; (3) decreased the expression of 5-HT_1A receptor in the amygdala without altering the transporter expression. Moreover, pretreatment with 0.1 mg/kg 8-hydroxy-di-n-propylamino tetralin, a selective 5-HT_1A receptor agonist, impaired the passive avoidance performance and completely abolished the exercise-enhanced fear memory. Our results suggest that down-regulation of the 5-HT system in the limbic system, i.e., the reduction of the hippocampus 5-HT content and the amygdala 5-HT_1A receptor expression, may be involved in the exercise-enhanced fear memory.     

初中生的自尊、受益者特征与亲社会行为的关系

以初中一至三年级学生为对象,采用自尊量表（SES）和帮助行为调查问卷进行测查,以探讨自尊、受助者特征对其亲社会行为的影响。结果表明：（1）在社会道德认知和自我意愿层面上,大多数初中生能表现出积极的亲社会性助人趋向,部分学生的行为决策判定具有不一致性;（2）初中生的自尊程度不影响对他人需要的注意、归因以及行为方式的选择,但与帮助行为的价值取向、行为意愿等认知、情感因素有关,能直接影响自主性的亲社会行为;（3）初中生有关潜在受益者特征的某种认知结果及其相应的情感体验,对帮助型亲社会行为趋向有重要影响;（4）初中生的自尊及其所知觉的潜在量益者特征在亲社会行为趋向中交互作用不显著。     

藏族本教与纳西族东巴教祭司的比较研究

藏族与纳西族的历史关系长达一千多年。本文通过对藏族本教与纳西族东巴教的宗教祭司、祖师传说、以及所使用法器的比较分析,说明两个民族、宗教之间有着密切的联系。     

对伦理学历史演变轨迹的一种概述(下)

康德在许多方面来说是从德性伦理学到义务论伦理学的联系环节.在义务论伦理学中正当(应当)成为核心的概念,基于对正当的不同解说,形成责任论与权利论两脉.康德学说是责任论的杰出典范;在权利论中,首先形成作为其古代先声的回应的近现代契约论伦理学,从这种传统中新近发展出程序论的伦理学.