老年高血压降压药物的选择

随着社会进入老龄化,我国老年高血压的绝对人数逐渐上升,目前我国60岁以上人群高血压的患病率为49％,80岁以上人群高血压的患病率为90％.高血压对于老年人的危害更为严重,老年高血压患者发生靶器官损害以及相关死亡的危险性显著增高,故合理地控制老年患者的血压,对于降低病死率,改善生活质量有着重要的意义.但老年高血压有其特殊的病理生理及临床特点,要求我们在治疗药物的选择上要兼顾多方面因素,合理用药,减少副作用,降低病死率.     

Mapping novel labels to actions: how the rhythm of words guides infants' learning

We investigated the effect of lexical stress on 16-month-olds' ability to form associations between labels and paths of motion. Disyllabic English nouns tend to have a strong-weak (trochaic) stress pattern, and verbs tend to have a weak-strong (iambic) pattern. We explored whether infants would use word stress information to guide word-action associations during learning. Infants heard two novel words with either verb-like iambic stress or noun-like trochaic stress. Each word was paired with a single novel object performing one of two path actions and was tested using path-switch trials. Only infants in the iambic stress condition learned the association between the novel words and the path actions. To further investigate infants' difficulty in mapping the trochaic labels to the actions, we conducted an additional study in which infants were given an object switch task using the trochaic labels. In this case, infants were able to associate the trochaic labels with the objects, providing further support that infants use lexical stress to guide label-referent associations. This study demonstrates that by 16months, English-learning infants have developed a bias to expect disyllabic action labels to have iambic stress patterns, consistent with native language stress patterns.     

A Review of Carolyn Chen’s <Emphasis Type="Italic">Getting Saved in America: Taiwanese Immigration and Religious Experience</Emphasis>

Becoming religious among immigrants to the U.S. is undoubtedly a complex transformation. It takes place with both external sociocultural conditions and internal spiritual and psychological volitions. While marveling at Carolyn Chen’s fine scholarship on Taiwanese immigrants’ conversion experience, this review offers a critical reading of Chen’s equation: becoming American = becoming religious or vice versa with the reviewer’s own experience as both an Asian immigrant and a cultural anthropologist. It also discusses Chen’s assessment of the gendered identity of both Asian-American men and women, be it religious, cultural, or political.     

Modulation of N400 in chronic non-fluent aphasia using low frequency Repetitive Transcranial Magnetic Stimulation (rTMS)

Low frequency Repetitive Transcranial Magnetic Stimulation (rTMS) has previously been applied to language homologues in non-fluent populations of persons with aphasia yielding significant improvements in behavioral language function up to 43 months post stimulation. The present study aimed to investigate the electrophysiological correlates associated with the application of rTMS through measurement of the semantic based N400 Event-related brain potentials (ERP) component. Low frequency (1 Hz) rTMS was applied to the anterior portion of the homologue to Broca’s area (pars triangularis), for 20 min per day for 10 days, using a stereotactic neuronavigational system. Twelve non-fluent persons with aphasia, 2-6 years post stroke were stimulated. Six participants were randomly assigned to receive real stimulation and six participants were randomly assigned to receive a blind sham control condition. ERP measures were recorded at baseline, 1 week and 2 months subsequent to stimulation. The findings demonstrate treatment related changes observed in the stimulation group when compared to the placebo control group at 2 months post stimulation indicating neuromodulation of N400 as a result of rTMS. No treatment related changes were identified in the stimulation group, when compared to the sham group from baseline to 1 week post stimulation. The electrophysiological results represent the capacity of rTMS to modulate neural language networks and measures of lexical-semantic function in participants with non-fluent aphasia and suggest that time may be an important factor in brain reorganization subsequent to rTMS.     

Higher-order factors of the Big Five predict exploration and threat in life stories

Research has not previously examined whether higher-order traits of the Big Five are related to characteristics of life story narratives. The current study explored possible links between the broad dispositions of Stability (comprising the shared aspects of Agreeableness, Conscientiousness, and Emotional Stability) and Plasticity (comprising the shared aspects of Extraversion and Openness) with narrative accounts of threat and exploration in the life-stories of 128 adults. Stability was inversely related to construals of threat in narratives, and Plasticity was positively related to exploration in narratives after controlling for the suppressor effects of demographic variables. These findings add to the research linking higher-order factors of the Big-Five to important domains as well as research linking dispositional traits to narrative identity.     

Objects and Levels: Reflections on the Relation Between Time-Consciousness and Self-Consciousness

The text surveys the development of the debate between Zahavi and Brough/Sokolowski regarding Husserl’s account of inner time-consciousness. The main arguments on both sides are reconsidered, and a compromise is proposed.     

Aversion to Happiness Across Cultures: A Review of Where and Why People are Averse to Happiness

A common view in contemporary Western culture is that personal happiness is one of the most important values in life. For example, in American culture it is believed that failing to appear happy is cause for concern. These cultural notions are also echoed in contemporary Western psychology (including positive psychology and much of the research on subjective well-being). However, some important (often culturally-based) facts about happiness have tended to be overlooked in the psychological research on the topic. One of these cultural phenomena is that, for some individuals, happiness is not a supreme value. In fact, some individuals across cultures are averse to various kinds of happiness for several different reasons. This article presents the first review of the concept of aversion to happiness. Implications of the outcomes are discussed, as are directions for further research.     

Neural correlates of sensory‐enabling presentation: An fMRI study of image zooming and rotation video effects on online apparel shopping

For experience products, such as apparel, sensory‐enabling presentations that provide a sense of tactile experience have been suggested as an effective strategy to reduce perceived risk and increase the likelihood of a pleasurable shopping experience. Using functional Magnetic Resonance Imaging (fMRI), we investigated whether sensory‐enabling presentations, specifically, image zooming and rotation videos, would evoke different cognitive and affective brain functions during product evaluation and purchase decision processes. The results suggested that whereas image zooming may evoke more visual perception in the product evaluation process, the rotation view evokes more mental imagery, pleasure, and reward anticipation during the purchase decision process. Copyright © 2014 John Wiley & Sons, Ltd.