Pathways to violence in the children of mothers who were depressed postpartum

The impact of postnatal depression on a child's risk for violent behavior was evaluated in an urban British community sample (N=122 families). Mothers were interviewed during pregnancy, at 3 months postpartum, and when the child was 1, 4, and 11 years of age. Mothers, teachers, and children reported on violent symptoms at age 11. Structural equation modeling revealed that the child's violence was predicted by the mother's postnatal depression even when her depression during pregnancy, her later history of depression, and family characteristics were taken into account. Violence was associated with symptoms of attention-deficit/hyperactivity disorder and problems with anger management. Children were most violent if mothers had been depressed at 3 months and at least once thereafter.     

Once hurt,twice hurtful: how perceived regard regulates daily marital interactions

A daily diary study examined how chronic perceptions of a partner's regard affect how intimates interpret and respond to daily relationship stresses. Spouses each completed a diary for 21 days. Multilevel analyses revealed that people who felt less positively regarded read more into stressful events than did people who felt highly regarded, feeling more hurt on days after acute threats, such as those posed by a moody or ill-behaved partner. Intimates who felt less valued responded to feeling hurt by behaving badly toward their partner on subsequent days. In contrast, intimates who felt more valued responded to feeling hurt by drawing closer to their partner. Ironically, chronically activated needs for belongingness might lead people who are trying to find acceptance to undermine their marriage.     

Endogenous shifts of covert attention operate within multiple coordinate frames: evidence from a feature-priming task

The locations of visual objects and events in the world are represented in a number of different coordinate frameworks. For example, a visual transient is known to attract (exogenous) attention and facilitate performance within an egocentric framework. However, when attention is allocated voluntarily to a particular visual feature (ie endogenous attention), the location of that feature appears to be variously encoded either within an allocentric framework or in a spatially invariant manner. In three experiments we investigated the importance of location for the allocation of endogenous attention and whether egocentric and/or allocentric spatial frameworks are involved. Primes and targets were presented in four conditions designed to vary systematically their spatial relationships in egocentric and allocentric coordinates. A reliable effect of egocentric priming was found in all three experiments, which suggests that endogenous shifts of attention towards targets defined by a particular feature operate in an egocentric representation of visual space. In addition, allocentric priming was also found for targets primed by their colour or shape. This suggests that attending to targets primed by nonspatial attributes results in facilitation that is localised in more than one coordinate frame of spatial reference.     

It does take a village: nonfamilial environments and children's behavior

Abstract - Family characteristics influence children's behavioral development, but so do variations in schools, neighborhoods, and communities. We documented extrafamilial environmental effects by fitting maximum likelihood models to questionnaire data collected from double dyads consisting of twins and their classmate controls. The classmate controls in each double dyad were genetic strangers living in separate households, but they shared school, neighborhood, and community environments with their yoked twin pair and with one another. At ages 11 to 12, the control classmates showed significant similarities in religious practices and smoking and drinking patterns, demonstrating that environmental influences outside the family affect children's behavioral development. Familial self-selection of residential neighborhoods may have contributed to these results, but direct effects of variation across communities, neighborhoods, and schools cannot be dismissed, and such effects warrant further study.     

Long-term memory formation in the chick requires mobilization of ryanodine-sensitive intracellular calcium stores

Training chicks (Gallus domesticus) on a one-trial passive avoidance task results in transient and time-dependent enhanced increases in N-methyl-d-aspartate- or alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionate-stimulated intracellular calcium concentration in synaptoneurosomes isolated from a specific forebrain region, the intermediate medial hyperstriatum ventrale. This increase could result from either calcium entry from the extracellular medium or from mobilization of intracellular calcium stores. We have therefore examined the effects of dantrolene, an inhibitor of calcium release from the intracellular ryanodine-sensitive store, on these processes. Dantrolene, 50 nmol per hemisphere injected intracerebrally 30 min pre- or 30 min posttraining, blocked longer term memory for the passive avoidance task, whereas memory for the task was unaffected when dantrolene was injected at earlier or later times. Preincubation of synaptoneurosomes, isolated from the intermediate hyperstriatum ventrale 10 min after training, with 100 nM dantrolene abolished the enhanced training-induced increase in intracellular calcium concentration elicited by 0.5 mM N-methyl-d-aspartate. By contrast, the training-induced enhancement of the alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionate-stimulated increase in intracellular calcium concentration in synaptoneurosomes prepared 6 h posttraining was unaffected by preincubation with dantrolene, which was not amnestic at this time. Calcium release from ryanodine-sensitive intracellular stores may thus be a necessary stage in the early phase of the molecular cascade leading to the synaptic modulation required for long-term memory storage.     

Can the Media Create Public Opinion? A Social-Identity Approach

The media remains a powerful presence in U.S. culture. It gives people news of world and local events, it entertains, and it may even function as a companion to children. Because it functions as a window to the outside world, what appears across its landscape actually may become people's reality. Thus, the potential for distorting their view of that world is high if the picture provided is unrepresentative of actual events. For example, the prevalence of violent acts on television has been linked to increased aggression and escalating impressions of a dangerous world, and the overrepresentation of youth and beauty may be a causal factor of eating disorders. In this article, we explore the possibility that the media may also serve as a powerful creator of the very public opinions it seeks to reflect in its news. Subtle nonverbal cues of newscasters have been shown to influence voting behavior, and the media's overrepresentation of the proportion of blacks in poverty may decrease whites' support of welfare. By portraying a world in which people's opinions are based on their ethnic or demographic group membership, the media may also subtly but powerfully create the very opinions they seek to reflect.     

Client Advocacy and Collaboration with Insurance and Laboratory Testing Agencies: A Case Study Illustrating Genetic Counselor Roles

Genetic counseling and the many roles a genetic counselor must assume to provide quality genetic health care are becoming increasingly complex, especially when the genetic condition is rare, and DNA testing is costly and not yet routinely used. A case study of a couple with a family history of retinoblastoma and their pursuit of DNA testing for prenatal diagnosis is presented. The case study illustrates the instrumental role of the genetic counselor in advocating for clients for genetic services such as DNA testing and in educating insurance companies in the nature and importance of such services to achieve improved client health care outcomes.     

Sequence-Specific Impairment of Memory Formation by NCAM Antisense Oligonucleotides

The functional role of NCAM gene expression in memory formation was studied in the one-trial passive avoidance task in day-old chicks by pretraining injections of one of three different 18-mer end-protected oligonucleotides corresponding to positions 190-, 207-, and 332- of the NCAM Ig1 domain. Twenty-four-hour-old chicks were trained by pecking at a bitter-tasting bead and tested for avoidance 30 min, 3, 8, or 24 hr later. Memory retention was significantly reduced only in the group of animals injected with the NCAM antisense corresponding to position 207- (AS-ODN-207), and only if given twice, both immediately after hatching and 12 hr before training. This antisense was without effect on the general behavior of the chicks, training or acquisition, and did not produce observable neurotoxic damage. Under such conditions amnesia was evident by 3 hr after training and lasted until at least 24 hr after training. The two other tested oligonucleotides were without behavioral effect. To control for nonsequence-specific effects of AS-ODN-207, brains from injected and trained animals were processed for Western blotting and probed using anti-NCAM, anti-L1, and anti-actin antibodies. NCAM antisense corresponding to position 207- significantly reduced the level of NCAM, whereas the level of L1 and actin remained unchanged. These results confirm our earlier conclusion that NCAM is necessary for longer term memory retention.