Role of the NO/sGC/PKG signaling pathway of hippocampal CA1 in morphine-induced reward memory

Evidence suggests that the nitric oxide (NO)/soluble guanylyl cyclase (sGC)/cGMP dependent protein kinase (PKG) signaling pathway plays a key role in memory processing, but the actual participation of this signaling cascade in the hippocampal CA1 during morphine-induced reward memory remains unknown. In this study, we investigated the role of the NO/sGC/PKG signaling pathway in the CA1 on morphine-induced reward memory using a conditioned place preference (CPP) paradigm. We found that rats receiving an intraperitoneal (i.p.) injection of 4mg/kg morphine exhibited CPP, whereas rats treated with only 0.2mg/kg morphine failed to produce CPP. Intra-CA1 injection of the neuronal NO synthase (nNOS) inhibitor 7-NI, the sGC inhibitor ODQ or the PKG inhibitor Rp-8-Br-PET-cGMPS had no effect on the acquisition of CPP by 4mg/kg morphine. Intra-CA1 injection of 7-NI blocked the consolidation of CPP induced by 4mg/kg morphine, and this amnesic effect of 7-NI was mimicked by ODQ and Rp-8-Br-PET-cGMPS. Intra-CA1 injection of the NOS substrate L-arg or the sGC activator YC-1 with an ineffective dose of morphine (0.2mg/kg, i.p.) elicited CPP. This response induced by L-arg or YC-1 was reversed by pre-microinjection of Rp-8-Br-PET-cGMPS in the CA1. These results indicated that the activation of the NO/sGC/PKG signaling pathway in the CA1 is necessary for the consolidation of morphine-related reward memory.     

虚假供述影响因素及法律控制

本文以虚假供述的研究方法为起点,结合案例,对自愿型、强迫—服从型和强迫—内化型三种类型的虚假供述进行介绍,从个人因素与情境因素两个方面,对虚假供述的影响因素加以分析。其中,着重阐述了虚假供述的实验室研究范式。在评析影响因素的基础上对我国刑事诉讼的修改提出立法建议,以期在法律上控制影响因素的作用。     

Shear band evolution during large plastic deformation of brittle and ductile metallic glasses

Four monolithic metallic glasses (MMGs) with different plasticities varying from brittle to ductile behavior under unconstrained loading were subjected to small punch testing. All specimens undergo large plastic deformation with multiple cobweb-like shear bands under these conditions. The process of shear band evolution was carefully controlled and investigated. Plasticity of MMGs is characterized by equivalent plastic strain ε* (product of shear band density and critical shear offset). Thus, this article provides an experimental basis for a better understanding of the shear band evolution during plastic deformation of MMGs.     

Parental Control, Adolescent Delinquency, and Young Adult Criminal Behavior

Adolescence and young adulthood are periods of increased autonomy. Higher levels of autonomy could increase the opportunities for risky behavior such as delinquency. During these periods of transition, the role of parental control becomes less clear. Previous studies have demonstrated the association between parental control and adolescent delinquency, but few have extended examination of such association into young adulthood. The purpose of the study is to examine the association between parental control and delinquency and parental control in adolescence and young adult criminal behavior. We propose that, even though adolescents seek autonomy during this stage, lack of parental control is positively associated with delinquency and has continued influence in young adulthood. Using a national longitudinal dataset, we analyzed the relationship between parental control and delinquency. Findings from regression analyses indicated that lack of parental control had a positive association with delinquency both concurrently and longitudinally into young adulthood. When analyzing delinquency in young adulthood, females reported a lower level of delinquency and younger age was associated with more delinquent behavior. Unexpectedly, parents’ college education was positively associated with delinquency in young adulthood. The findings suggest that parental control is still influential through the period of adolescence and early parental control is still influential in young adulthood. Ways to practice parental control and implications of results are further discussed.     

小学生对不同词语类型预视加工的发展*

采用边界范式,以60名小学生为被试,探讨了小学生不同词语类型的预视效应。结果表明:(1)五年级学生表现出更高的阅读效率;(2)预视类型的主效应显著,出现明显的预视效应;(3)不同词语类型的预视效应差异不显著;(4)未出现副中央凹-中央凹效应。研究结果支持阅读眼动的序列加工模型。     

从恢复体验到地方依恋:环境偏好与居住时长的作用

探究源自环境的恢复体验(如,放松、平静等)对居住者地方依恋(包括地方依赖和地方认同两个维度)的预测作用,并分析其中的内在过程与情境条件。采用问卷研究法(N=410),结果发现:(1)恢复体验能显著正向预测个体地方依恋;(2)环境偏好在恢复体验与地方依恋之间起完全中介作用;(3)居住时长调节环境偏好与地方依恋(主要是地方认同)之间的关系。研究将有助于探寻环境心理学视角下的压力管理与城市管理协同路径。     

Bootstrap standard error and confidence intervals for the correlations corrected for indirect range restriction

The standard Pearson correlation coefficient, r, is a biased estimator of the population correlation coefficient, ρ(XY) , when predictor X and criterion Y are indirectly range-restricted by a third variable Z (or S). Two correction algorithms, Thorndike's (1949) Case III, and Schmidt, Oh, and Le's (2006) Case IV, have been proposed to correct for the bias. However, to our knowledge, the two algorithms did not provide a procedure to estimate the associated standard error and confidence intervals. This paper suggests using the bootstrap procedure as an alternative. Two Monte Carlo simulations were conducted to systematically evaluate the empirical performance of the proposed bootstrap procedure. The results indicated that the bootstrap standard error and confidence intervals were generally accurate across simulation conditions (e.g., selection ratio, sample size). The proposed bootstrap procedure can provide a useful alternative for the estimation of the standard error and confidence intervals for the correlation corrected for indirect range restriction.     

小学生领导力萌芽与发展的实证研究

摘 要 本研究以四年级学生为研究对象,通过话语分析,探究了八个无领导小组八次讨论过程中领导力的萌芽状况及其影响因素。结果发现,小学生可自发出现领导力行为,但只有两个小组会涌现出明显的领导者,并表现为独立领导和协同领导两种不同模式。对学生和教师行为的综合分析显示,学生领导力的形成与教师示范、反馈及同伴互动存在密切关系,这对学生领导力的培养具有重要的启示意义。     

辩证法心理学发展的曲折道路与新机遇

当前国际上所兴起辩证法心理学研究的热潮对于克服当代心理学的深层困境,推动理论心理学研究与重建心理学理论具有重要意义。然而辩证法心理学的发展道路并不平坦,其根源在于以下事实:1)科学实证主义的"无矛盾"原理与辩证法是格格不入的;2)当代辩证法心理学理论并不是完美的,其本身还存在弊端。当今由于社会建构论的兴盛与理论心理学的复兴为辩证法心理学的发展又提供了新的机遇。     

中国人的人格特点(Ⅱ):善良

该研究的目的是探讨不同性别、年龄、职业和婚姻状况的被试在善良人格维度上的特点。1276名被试在中国人人格量表（QZVS）的善良维度上的分数存在不同程度的性别、年龄、职业和婚姻状况差异,其中尤以性别和年龄的影响最大,年龄和职业的交互作用明显,而且婚姻状况会明显影响个体1的重感情倾向。文中还讨论了善良人格维度差异的意义以及将来研究的方向。