Altered Emotional Processing in Pediatric Anxiety,Depression, and Comorbid Anxiety-Depression

The goal of this study was to examine some of the mechanisms underlying emotion regulation in childhood affective disorders by examining the impact of distracting emotional information during performance on a working memory task (Emotional n-back or E-n-back). The sample included 75 children (38 girls and 37 boys) between 8 and 16 years of age meeting criteria for: Anxiety disorder (ANX, n = 17), Major depressive disorder (MDD, n = 16), Comorbid anxiety and depression (CAD, n = 24), or Low-risk normal control (LRNC, n = 18). Results showed that the MDD and CAD groups had significantly longer reaction times on negative emotional backgrounds compared to neutral backgrounds, whereas the LRNC group had significantly longer reaction times on positive backgrounds. These results suggest altered processing of emotional information particularly associated with depression. Because the E-n-back task engages higher-order cognitive processes, these results suggest that these alterations in processing emotional information also interfere with the cognitive processes that govern how attentional resources are allocated. Further, research is needed to replicate this study and delineate underlying neural mechanisms.     

Affect regulation, brain development, and behavioral/emotional health in adolescence

This paper addresses the importance of affect regulation (AR) in relation to a broad range of behavioral and emotional health problems that emerge during adolescence. AR is defined as the adaptive modulation of emotional experience to serve a goal or purpose. This conceptualization of AR emphasizes the use of cognitive skills to guide, inhibit, or modify emotion and behavior, including the expression of emotional responses, in learned, strategic ways-skills that ultimately underpin adult levels of social maturity and the ability to show "responsible" behavior across a range of emotional situations. Neurobehavioral systems that subserve these AR skills include areas of the inferior and orbital prefrontal cortex (PFC), with rich interconnections to several limbic structures and other cortical areas, including the dorsolateral PFC. Adolescence represents an important developmental period in the functional maturation of adult AR skills; it is also a critical time in the development of clinical disorders of AR (eg, rates of depression increase dramatically and gender differences in depression emerge). Maturational changes in AR that occur during adolescence-particularly with respect to the role of emotions influencing responsible decision making-are also relevant to understanding key aspects of the developmental pathways of some behavioral health problems, such as alcohol use and nicotine dependence. A strong case is made for developmental research in affective neuroscience aimed at this important maturational period, particularly the kind of transdisciplinary research leading toward mechanistic understanding of the development of adolescent-onset disorders. Improving understanding in these areas could ultimately lead to the development of early interventions in targeted high-risk populations, and has enormous clinical and social policy relevance.     

Intimate partner abuse of educated,employed black South African women: sociocultural factors

This study aimed to explore the influence of African culture and tradition on the abuse experiences of Black South African women who are educated and employed. Interviews were conducted with seven Black South African women (age range 38 to 47) who are college educated and employed. All participants were married for seven or more years and self-reporting to be in an abusive relationship. Interviews were transcribed verbatim and analysed using thematic content analysis. The results indicate sociocultural factors such as patriarchal values within their culture as an underlying reason for their husbands’ abusive behaviour. Abuse seemed likely when the women perceived gender roles that were in conflict with their husband's gender role expectations of them. The cultural expectation that women should not leave a marriage appeared to play an implicit role in their staying in an abusive relationship.     

Audit of the Informed Consent Process as a Part of a Clinical Research Quality Assurance Program

Audits of the informed consent process are a key element of a clinical research quality assurance program. A systematic approach to such audits has not been described in the literature. In this paper we describe two components of the audit. The first is the audit of the informed consent document to verify adherence with federal regulations. The second component is comprised of the audit of the informed consent conference, with emphasis on a real time review of the appropriate communication of the key elements of the informed consent. Quality measures may include preparation of an informed consent history log, notes to accompany the informed consent, the use of an informed consent feedback tool, and the use of institutional surveys to assess comprehension of the informed consent process.     

Beginning,ending and remembering

Wittgenstein famously opens his Philosophical Investigations with a quotation in which Augustine recounts how he acquired language. Instead of going into the widely discussed question of how Wittgenstein relates to Augustine's picture of language, this article inquires into what else might be at stake in invoking Confessions at the very beginning of his work. At the very least, such a gesture seems to suggest that Wittgenstein wants to inscribe himself into the Augustinian legacy. More specifically, this article argues that Philosophical Investigations centres on three problems that Wittgenstein has inherited from Augustine – namely what one might call the problem of beginning, the problem of ending and finally the problem of memory. The problem of beginning not only points to the local problem of how to start writing confessional philosophy, but also what authorizes such philosophy in the first place. The problem of ending concerns the direction of such philosophy and the problematic stance of its goal, while the problem of memory turns on the task of progressing from beginning to ending.     

Vitamin D and executive function: a preliminary report

The aim of this study was to investigate the relationship between vitamin D levels and cognition, both executive and nonexecutive functions, in men incarcerated in a Norwegian prison. Participants were divided into high vitamin D and low vitamin D groups based on established criteria (high level > or = 50 nmol/L; low level < 50 nmol/L). The mean vitamin D concentration was 69 (SD = 12) and 38 (SD = 9) nmol/L in the high-level group (n = 14) and the low level group (n = 11), respectively. Results revealed that the high vitamin D group had significantly more correct responses than the low vitamin D group on the executive function task. There was no difference between the groups on the nonexecutive function task. The reaction time data indicated that the high levels of correct responses in the high vitamin D group on the executive function tasks were not due to a speed-accuracy trade-off.     

Preschoolers distribute scarce resources according to the moral valence of recipients' previous actions

Children aged 3 years and 4? years old watched a puppet, struggling to achieve goals, who was helped by a 2nd puppet and violently hindered by a 3rd. The children then distributed wooden biscuits between the helper and hinderer. In Experiment 1, when distributing a small odd number of biscuits, 4?-year-olds (N = 16) almost always gave more to the helper. Children verbally justified their unequal distributions by reference to the helper's prosocial behavior or the hinderer's antisocial behavior. In Experiment 2, when biscuits were more plentiful, 4?-year-olds (N = 16) usually gave equal numbers to helper and hinderer, indicating that 4?-year-olds usually preferred not to distribute unequally unless forced to by resource scarcity. Three-year-olds (N = 16 in Experiment 1, N = 20 in Experiment 3) gave more biscuits equally often to the helper and to the hinderer. In many cases, this was because they were confused as to the identities and actions of the puppets, possibly because they were shocked by the hinderer's actions. Two fundamental moral behaviors are therefore demonstrated in young preschoolers: indirect reciprocity of morally valenced acts and a preference for equality when distributing resources, although the cognitive bases for these behaviors remain unclear. These results join other recent studies in demonstrating that the seeds of complex moral understanding and behavior are found early in development.     

Emotional difficulties in seventh grade children in Denmark

The present study investigates the prevalence of emotional difficulties and quality of life in a sample of 834 children from 56 seventh grade (aged 12-14 years) classes. Data was derived from a study of mental well-being developed by the National Council for Children, Denmark. The sample selection ensured that the children were nationally representative. Data was collected using the Strength and Difficulties Questionnaire (SDQ) and the Health Behaviour in School-aged Children (HBSC). Results indicated that 10.8% of children had concerns regarding emotional difficulties (6.6% definite concern; 4.2% some concern), and that significantly more girls than boys (44 girls and 10 boys) reported this concern. A novel finding was that emotional difficulties were related to children's perception of having low quality of life. Findings furthermore suggested that children's perception of a low home economy, less time spent on leisure activities, and female gender were all associated with emotional difficulties.     

Validity of the Finnish version of the Parental Burnout Assessment (PBA)

The aim of the present study was to validate the Finnish version of the Parental Burnout Assessment (PBA) using data from 1,688 Finnish parents (91% mothers) living in Finland with at least one child living at home. Confirmatory factor analyses supported the theoretical four-factor structure of the PBA – emotional exhaustion in one’s parental role, contrast with previous parental self, feelings of being fed up with one’s parental role, and emotional distancing from one’s children. Internal consistency for the total scale was excellent (Cronbach’s alpha ≥ 0.90) and for the subscales from acceptable (alpha ≥ 0.70) to excellent. The results further demonstrated strict factorial invariance of PBA across genders and educational status groups. Finally, the PBA and its four subscales correlated as expected with the three criteria variables (depressive symptoms, sleep disruptions, and self-esteem), the latent factors of all three criteria variables being still clearly unique and separate constructions from parental burnout factors.