Neuroleptic-resistant schizophrenics

According to Crow's postulated positive-negative distinction, negative symptoms of schizophrenia are less responsive to neuroleptic drugs. Not all research evidence supports that expectation, however, so that neuroleptics need not be withheld from any schizophrenic patients. Other aspects of Crow's hypothesized distinction have indicated possible promising results, but more research is required.     

The design,development, and implementation of a microprocessor-based ECG analysis system

This paper describes the research effort to design, develop, and implement a microprocessor-based ECG data acquisition, reduction, and analysis system for operation in real-time. This unit can be attached to three-channel ECG carts and provide an immediate on-site analysis. The basic design and development efforts include (1) the data acquisition, reduction, and matrix assembly, (2) ECG arrhythmia, P-wave, and axis analysis, (3) ECG contour analysis, and (4) a real-time three-channel data acquisition unit. Decision tables are used in the analysis. The implementation of these projects into a small microprocessor-based unit coupled to a three-channel recorder is now in progress. This system, coupled with a small printer, will provide immediate on-site ECG analysis for most cardiovascular dysfunctions.     

The removal and restoration of stimulus control

When a well-learned circle versus ellipse discrimination was made impossibly difficult for the subjects (rhesus monkeys), the controlling stimulus-response topographies were replaced by competing topographies. The identification of two training conditions sufficient to reinstate the original discrimination permitted the following inferences: the original controlling topography had merely decreased in probability of occurrence, whereas the "strength" of the stimulus-response relation remained unchanged; discriminations along the apparently continuous circle-ellipse dimension actually involved several distinct stimulus-control topographies.     

The comprehension of rate-incremented aural coding

Stimulus and psychological measures of a battery of 36 rate-manipulated versions of an extended message indicate that optimization of the efficiency of aural coding beyond that previously reported can be accomplished by the simultaneous application of a combination of natural and artificial distortions of the durational characteristics of speech. Peak efficiency of listening was successfully pushed to 400 wpm (words per minutes) primarily by means of a selective reduction of speech pause time. Regression estimates predicting the influence of pause time, total duration, and talker rate upon judgments of speech rate and comprehension are presented and implications for listening strategies and speech apperception drawn.This research was supported by grant HD02417 from the National Institute of Child Health and Human Development.