The assessment of cortisol using salivary ultrafiltrate

Cortisol can be used to indicate stress level as well as to monitor certain disease states. Although cortisol can be sampled from blood and urine, saliva sampling has decided advantages. Unfortunately, whole saliva contains a number of substances that can metabolize or bind with cortisol, potentially confounding analysis and quantitation. We introduce a semipermeable pouch that accumulates a contaminant-free salivary ultrafiltrate, thereby overcoming a number of the problems encountered with whole saliva. In three studies, we demonstrate accuracy and utility of the device for cortisol determination: (1) in an artificial medium, 60%–77% of the cortisol was recovered in the ultrafiltrate; (2) in vivo, ultrafiltrate cortisol correlated highly with whole-saliva cortisol collected under ideal conditions; and (3) ultrafiltrate cortisol evinced positive relationships with depression and cigarette use, consistent with studies in the literature. We conclude that this device and saliva-filtering technologies in general are useful in applications requiring quantitation of cortisol.     

Misalignment effects in 3-D versions of Poggendorff displays

Strong misalignment effects are found in three-dimensional (3-D) versions of Poggendorff displays viewed binocularly. The components of the standard 2-D Poggendorff figure—the parallels and the oblique segments—were presented in 3-D depth as a flat rectangular object with occluding edges and an oblique line situated behind the object. Three experiments investigated the misalignment effects under three different observation instructions: Subjects were told to look at the oblique (Experiment 1), at the rectangle (Experiment 2), or at the background (Experiment 3). Experiments 1 and 2 examined the effects on judgments of alignment of varying the distance in depth that separates the oblique from the rectangle. Experiment 3 examined the effects of varying the distance between the fixated background and the 3-D Poggendorff figure. Both standard and reversed misalignment effects were obtained. When the viewing condition produces crossed disparity for the oblique, perceived misalignment occurs in the usual Poggendorff direction, but it is reversed with uncrossed disparity. Moreover, the amount of misalignment is related to the amount of disparity, and it can be much stronger than is usual in the 2-D versions of the Poggendorff. The misalignment effects can be explained by binocular integration to produce a single cyclopean image.     

Male-female differences in sexual fantasy

A questionnaire about thoughts and ideas during sexual activity was returned by 51 females and 50 males in a random sample of college undergraduates. A high response rate (91%) and the similar sexual experience of male and female respondents make possible a strong conclusion about the college population sampled: Males are thinking more about past experiences and current behavior, while females are thinking more of imaginary experiences. This difference occurs for thoughts during masturbation as well as for thoughts during heterosexual activity. It appears that females prefer a different kind of sexual fantasy than males, rather than being generally less interested in sexual fantasy as claimed by Kinsey, Pomeroy, Martin, and Gebhart (Sexual behavior in the human female, Philadelphia: Saunders, 1953).     

Effects of target monitoring on understanding fluent speech

Phoneme monitoring and word monitoring are two experimental tasks that have frequently been used to assess the processing of fluent speech. Each task is purported to provide an “online” measure of the comprehension process, and each requires listeners to pay conscious attention to some aspect or property of the sound structure of the speech signal. The present study is primarily a methodological one directed at the following question: Does the allocation of processing resources for conscious analysis of the sound structure of the speech signal affect ongoing comprehension processes or the ultimate level of understanding achieved for the content of the linguistic message? Our subjects listened to spoken stories. Then, to measure their comprehension, they answered multiple-choice questions about each story. During some stories, they were required to detect a specific phoneme; during other stories, they were required to detect a specific word; during still other stories, they were not required to monitor the utterance for any target. The monitoring results replicated earlier findings showing longer detection latencies for phoneme monitoring than for word monitoring. Somewhat surprisingly, the ancillary phoneme- and word-monitoring tasks did not adversely affect overall comprehension performance. This result undermines the specific criticism that on-line monitoring paradigms of this kind should not be used to study spoken language understanding because these tasks interfere with normal comprehension.     

The Effects of Actual Behavior vs. Mere Labelling in Attribution of Sex Differences

A recurrent problem in interpreting research showing differential reactions to the sexes is that such results may reflect real behavior differences among those observed or differential expectations of those observing. This study used a methodology which allowed these two competing explanations to be tested by assessing whether subjects' ratings of taped interactants whose gender was ambiguous would be determined mainly by what gender the subjects thought the interactants were or by the interactants' behavior. The results showed that the causes of the sex differences in assessments differed depending on what type of assessment was being made. Specifically, behavior differences and not observers' expectations about such differences largely determined observers' ratings of specific attributes of the interactants, but observers' expectations and not behavior differences determined observers' general ratings of masculinity/femininity.     

Transfer of training of a new linguistic contrast in voicing

The present study examined the plasticity of the human perceptual system by means of laboratory training procedures designed to modify the perception of the voicing dimension in synthetic speech stimuli. Although the results of earlier laboratory training studies have been ambiguous, recently Pisoni, Aslin, Perey, and Hennessy (1982) have succeeded in altering the perception of labial stop consonants from a two-way contrast in voicing to a three-way contrast. The present study extended these initial results by demonstrating that experience gained from discrimination training on one place of articulation (e.g., labial) can be transferred to another place of articulation (e.g., alveolar) without any additional training on the specific test stimuli. Quantitative analyses of the identification functions showed that the new perceptual categories were stable and displayed well-defined labeling boundaries between categories. Taken together with the earlier findings, these results imply a greater degree of plasticity in the adult speech processing system than has generally been acknowledged in past studies.     

Hemiplegic writing in severe aphasia

Three patients with severe aphasia and right hemiplegia are described who could write to dictation with the right arm using a limb prosthesis though agraphic with the "intact" left hand. The phenomenon of "hemiplegic writing" is explained as an access to submerged or preprocessing levels in language and action structure, through the use of older proximal motor systems. This interpretation has implications for our understanding of language and brain function, as well as for approaches to the treatment of patients with severe language disorders.