Systemic administration of a nitric oxide synthase inhibitor impairs fear sensitization in the plus-maze

The aim of the present study was to evaluate the occurrence of fear sensitization in rats previously treated with an inhibitor of the NO syntheses and submitted to Trial1/Trial2 plus-maze (PM) procedure. Male Wistar rats received a systemic treatment with N(omega)-nitro-L-Arginine-methyl ester (L-NAME; 5, 10 or 50 mg kg(-1)) and were submitted to PM Trial1. In the following day the animals were re-exposed to the PM with no drug administration (Trial2). Some standards spatial-temporal measures, such as the percentage of entries (% Open arm entries) and time spent (% Open arm time) in the open arms and risk assessment frequency were recorded and used to estimate the animal level of fear sensitization in PM Trial2. The results showed that animals receiving L-NAME (50 mg kg(-1)) displayed increased % Open arm entries and % Open arm time in Trial2 in relation to the group receiving 0.9% saline, which is compatible with impaired fear/anxiety acquisition during Trial1/Trial2 PM procedure. In addition, rats treated with L-NAME (50 mg kg(-1)) exhibited low level of risk assessment in Trial2 in relation to the group treated with 0.9% saline, which indicates low level of fear/anxiety during PM re-exposure. The number of entries into the enclosed arms was not changed by any L-NAME treatment, which suggests no bias of the drug treatments on animal locomotor activity. The data suggest that NO synthesis may mediate the fear sensitization process in the PM.     

Sunk-cost effects on purely behavioral investments

Although the sunk-cost effect is a well-documented psychological phenomenon in monetary investments, existing literature investigating behavioral investments (e.g., time, effort) has not replicated this effect except when such investments relate to monetary values. The current explanation for this discrepancy proposes that purely behavioral sunk-cost effects are unlikely to be observed because they are difficult to book, track, and balance in a mental account. Conversely, we argue that, through an effort-justification mechanism, people account for the amount of behavioral resources invested when selecting an alternative, in which case they may fall prey to purely behavioral sunk-cost effects. The results of two experiments support this prediction. Because many decisions involve behavioral investments, behavioral sunk-cost effects should be pervasive psychological phenomena.     

How individualism–collectivism orientations predict happiness in a collectivistic context

We discuss how individualistic/collectivistic orientations of employees predict affective well-being at work, and how this relationship is moderated by the perceptions of spirit of camaraderie in organizations. The sample comprises 161 employees of 109 organizations operating in Portugal, a collectivistic culture. The findings suggest that: (a) collectivistic individuals show higher affective well-being than individualists; (b) this relationship is moderated by the employees’ perceptions of the spirit of camaraderie in their organizations; (c) higher affective well being levels tend to be experienced by collectivists who find working in an organizational context to be rich in spirit of camaraderie, and lower levels of affective well being are expressed by individualists who perceive poor spirit of camaraderie in their working environments. The paper emphasizes that employee happiness can have different bases in different cultures and that individualism/collectivism orientations do not operate in the same way in different cultural and organizational contexts. We are very grateful to the three anonymous reviewers for their helpful comments and suggestions.     

Organisational Justice and Citizenship Behaviors: A Study in the Portuguese Cultural Context

Theoretical and empirical evidence suggests that justice and organisational citizenship behaviors (OCB), as well as the relationship between them, are not culture free. However, most studies have been carried out in parts of Asia and Northern Europe, and especially in the USA, shedding little understanding on the dynamics of justice and OCB in less‐studied contexts. We show how four dimensions of organisational justice predict four dimensions of OCB in an under‐studied context—Portugal, a feminine, collectivistic, high power distance and low performance‐oriented culture—a profile that is antipodal to that of US culture. A sample of 269 employees reported their justice perceptions, their OCBs being described by supervisors. The findings suggest that: (a) employees are more sensitive to the interactional dimensions of justice than to the procedural and distributive ones; (b) among the interactional dimensions, the interpersonal one is more predictive of some OCB dimensions than the informational one. Des données théoriques et empiriques suggèrent que la justice et les comportements de citoyenneté organisationnelle (OCB), tout comme la relation entre eux, ne sont pas sans base culturelle. Toutefois, la plupart des études ont été menées dans certaines parties de l’Asie, de l’Europe du Nord, et plus particulièrement aux USA, ce qui restreint la compréhension des dynamiques de la justice et des OCB qui peuvent être appréhendés dans d’autres contextes. Nous montrons comment 4 dimensions de la justice organisationnelle prédisent 4 dimensions des OCB dans un contexte peu étudié—le Portugal, une culture féminine, orientée vers la collectivité, avec une forte distance au pouvoir et de faibles performances—, un profil aux antipodes de la culture américaine. Chacun des 269 employés de l’échantillon indique ses perceptions de la justice, ses OCB ont été décrits par ses supérieurs. Les résultats montrent que (a) les employés sont plus sensibles aux dimensions interactionnelles de la justice qu’à celles procédurales et distributives (b) parmi les dimensions interactionnelles, l’interpersonnelle est plus prédictive de certaines dimensions des OCB plutôt que l’informationnelle.     

Post-training down-regulation of memory consolidation by a GABA-A mechanism in the amygdala modulated by endogenous benzodiazepines

In rats, amygdala benzodiazepine-like immunoreactivity decreases by 29% immediately after the animals step down from the platform of an inhibitory avoidance apparatus and decreases by a further 45% immediately after they receive a training footshock. The decrease is attributable to a release of diazepam or diazepam-like molecules. The immediate post-training intraamygdala injection of the central benzodiazepine antagonist flumazenil (10 nmole/amygdala) causes memory facilitation, and that of the GABA-A agonist muscimol (0.005 to 0.5 nmole) causes retrograde amnesia. Pretraining ip flumazenil administration (2.0 and 5.0 mg/kg) attenuates the effect of post-training muscimol by a factor of at least 100. The higher dose of pretraining flumazenil also causes memory facilitation. The data suggest that post-training consolidation is down-regulated by a GABA-A mechanism in the amygdala modulated by endogenous benzodiazepines released during training and at the time of consolidation.     

Evidence for the substantia nigra pars compacta as an essential component of a memory system independent of the hippocampal memory system

The aim of the present study was to test if the nigrostriatal pathway is an essential component for a water maze cued task learning and if it works independently of the hippocampal memory system. This hypothesis was tested using an animal model of Parkinson's disease in which male Wistar rats were lesioned in the substantia nigra pars compacta (SNc) by the intranigral infusion of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP), thus causing a partial depletion of striatal dopamine. SNc-lesioned and sham-operated animals were implanted bilaterally with guide cannulae above the dorsal hippocampus in order to be tested after the administration of 0.4 microl 2% lidocaine or saline into this structure. The animals were tested in a spatial or in a cued version of the water maze, memory tasks previously reported to model hippocampal-dependent spatial/relational and striatal-dependent S-R learning, respectively. Hippocampal inactivation, but not SNc lesion, impaired learning and memory in the spatial version of the water maze. An opposite situation was observed with the cued version. No significant interaction was observed between the SNc lesion and hippocampal inactivation conditions affecting scores in the spatial or in the cued version of the water maze. These results suggest that the nigrostriatal pathway is an essential part of the memory system that processes S-R learning and that it works independently of the hippocampal memory system that processes spatial/relational memories.     

They Need to be Different, They Feel Happier in Authentizotic Climates

The study shows how the perceptions of six authentizotic climate dimensions (spirit of camaraderie, trust and credibility of the leaders, open and frank communication with the leaders, opportunities for learning and personal development, fairness/justice, and work-family conciliation) interact with the need for uniqueness (NFU) in predicting affective well-being (AWB) at work. Participants are 342 individuals, all young graduate engineers participating in a course on ethics and deontology. Both the perceptions of authentizotic climates and the NFU predict unique variance of AWB. Perceptions of authentizotic climates (excepting work-family conciliation) interact with NFU in predicting AWB: (a) the relationship between perceptions of authentizotic climates and AWB is stronger when NFU is greater; (b) the relationship between NFU and AWB is stronger when perceptions of authentizotic climates are more positive.     

The Mediator Role of Emotion Regulation Processes on Infertility-Related Stress

The objective of this study is to investigate gender differences regarding the mediator role of self-compassion and self-judgment on the effects of external shame, internal shame, dyadic adjustment, on infertility-related stress. One hundred and sixty-two women and 147 men with a primary infertility diagnosis completed the following set of self-report measures: Others as Shamer, Experience of Shame Scale, Dyadic Adjustment Scale, Self-Compassion Scale, and Fertility Problem Inventory. Path analyses results revealed that in women self-compassion fully mediated the effect of internal shame on infertility-related stress and partially mediated the effect of dyadic adjustment on this variable, while external shame had only a direct effect. In men self-judgment fully mediated the effect of external and internal shame on infertility-related stress. Dyadic adjustment had only a direct effect on infertility-related stress. In conclusion, there is a distinct role of self-compassion and self-judgment on the relationship between shame and infertility-related stress in men and women. Such differences should be taken into account in psychological interventions with these patients. Future research is warranted to further support our results.     

Co-referential Processing of Pronouns and Repeated Names in Italian

In this study, we investigate whether co-referential processing across sentence boundaries is driven by universal properties of the general architecture of memory systems and whether cross-linguistic differences concerning the number of anaphoric forms available in a language’s referential inventory can impact the process of inter-sentential co-reference resolution. As a window into these questions, we test whether the repeated-name penalty (RNP) and the overt-pronoun penalty (OPP)—comprehension delays associated with repeated names and overt pronouns, respectively, in comparison to more reduced anaphoric forms in reference to salient antecedents—occur in Italian, examining the extent to which Italian resembles other null-subject languages, with focus on Spanish. Our self-paced reading experiment with factors Antecedent (Subject, Object) and Anaphor (Null Pronoun, Overt Pronoun, Repeated Name) found that Italian exhibits both an OPP and a (weaker) RNP, extending previous research that showed these effects in Spanish and strengthening the claim that co-reference resolution might be subject to universal principles.