The role of the dorsal striatum and dorsal hippocampus in probabilistic and deterministic odor discrimination tasks

Three experiments explored the contribution of the cortico-striatal system and the hippocampus system to the acquisition of solutions to simultaneous instrumental odor discriminations. Inactivation of the dorsal striatum after rats had reached criterion on a three problem probabilistic set of discriminations--A (80%) vs. B (20%), C (67%) vs. D (33%), E(67%) vs. F(33%)--impaired test performance and disrupted performance when the rats were tested with novel cue combinations (C vs. F and E vs. D), where control animals chose C and F. In contrast, inactivating the dorsal hippocampus enhanced performance on this task and on a deterministic discrimination A (100%) vs. B (0%). These results are consistent with the complementary learning systems view, which assumes that the cortico-striatal and hippocampal system capture information in parallel. How this information combines to influence task performance depends on the compatibility of the content captured by each system. These results suggest that the trial-specific information captured by the hippocampal system can be incompatible with the across-trial integration of trial outcomes captured by the cortico-striatal system.     

Is there a baby in the bathwater? Maybe: some methodological issues for the de novo protein synthesis hypothesis

The de novo protein synthesis hypothesis has a long history and will no doubt continue to influence research. Yet, the primary behavioral evidence for this claim continues to come from studies in which amnesia is produced by broad scale protein synthesis inhibitors such as anisomycin. What is remarkable is the uncritical acceptance of the idea that because anisomycin is a protein synthesis inhibitor then it must have produced amnesia because it prevented translation. Several viable alternative interpretations of such experiments are discussed here and it is concluded that there is nothing to be gained by the continued use of broad-scaled antibiotics to address this hypothesis. Moreover, this approach cannot answer two critical and related questions - why must new proteins be synthesized and what are they? A focus on specific proteins such as those synthesized locally and upregulate the translation of other proteins may be a promising approach to answering these questions.     

The Effects of Trait Driving Anger, Anonymity, and Aggressive Stimuli on Aggressive Driving Behavior

We examined the effects of trait driving anger, aggressive stimuli, and anonymity on aggressive driving behavior in a driving simulation task. High and low driving anger participants were randomly assigned to one of four conditions: (a) anonymous vs. identifiable driver; and (b) exposure to aggressive stimuli versus nonaggressive stimuli. Participants drove more aggressively when they were anonymous (d = .28) and exposed to aggressive stimuli (d = .05). Males drove more aggressively than did females (d = .06). No main or interaction effects were found for trait driving anger. Results suggest that situational factors affecting other forms of aggression are also important in aggressive driving.     

'To Whom Much Has Been Given...': Religious Capital and Community Voluntarism Among Churchgoing Protestants

Research on volunteering behavior has consistently found a positive relationship between religion and volunteering. Using a sample of churchgoing Protestants (N=1,738)from the Religious Identity and Influence Survey we examine the specific influences of religiosity, religious identity, religious socialization, and religious social networks on local volunteer activity in church programs and non-church organizations, as well as general volunteering tendencies. These influences are presented within the theoretical framework of religious capital. Logistic regression techniques were applied to determine the strength of the contribution of these influences while accounting for basic background factors. Findings suggest that churchgoing Protestants are influenced by all measures to some degree, but religiosity (specifically participation in church activities) remains the strongest influence. Significant religious influences overall are most pronounced within the context of church-related volunteering which suggests that churchgoing Protestants exhibit a strong sense of community identity through their local churches. A discussion of these results and their implications for volunteering follows.     

Individual Religiosity,Moral Community,and Drug User Treatment

Some scholars have suggested that individual religiosity inhibits deviant behavior. Others have suggested that behavior is more responsive to the influence of religiously‐oriented moral communities than to the religiosity of individuals. Still others have suggested that non‐religious moral communities, such as sports teams or self‐help recovery groups, are just as effective as religious moral communities. The current article examines the associations between addicts' reductions in drug and alcohol use and religiosity, increase in church attendance, and increase in addiction self‐help recovery group attendance, following participation in publicly funded treatment programs. Results indicate that increase in self‐help recovery group attendance and church attendance were independently associated with reduction in alcohol use. Only increase in church attendance was significantly associated with reduction in cocaine use. Self‐assessed religious conviction was not associated with changes in drug use.     

Multiple Belief Systems in Psychotherapy: The Effects of Religion and Professional Beliefs on Clinical Judgment

This study examined the effects of religious and professional beliefs on clinical judgment. Eighty-seven psychotherapists completed a religious belief survey and a professional belief survey, as well as a questionnaire concerning internal conflict between professional and religious beliefs. The subjects then read two brief vignettes, describing a religious and a non-religious patient, and rated the patients with regard to optimism or pessimism concerning responsiveness to treatment. The results showed that there was no significant relationship between religious and professional beliefs. However, the strength of religious beliefs predicted optimism for the religious patient. In addition, there was a significant interaction effect between strength of religious beliefs and strength of professional beliefs on clinical ratings.     

Review Essay

Belief in God in an Age of Science , by John Polkinghorne
Genes, Genesis and God: Values and their Origins in Natural and Human History , by Holmes Rolston, III
The Genetic Gods: Evolution and Belief in Human Affairs , by John C. Avise     

Conflict Between Religion and Science Among Academic Scientists?

Using new survey data ( N = 1,646), we examine the attitudes academic scientists at 21 elite U.S. research universities have about the perceived conflict between religion and science. In contrast to public opinion and scholarly discourse, most scientists do not perceive a conflict between science and religion. Different from what other studies would indicate, this belief does not vary between social and natural scientists. We argue that maintaining plausibility frameworks for religion is an important correlate of whether scientists will reject the conflict paradigm, with such frameworks taking surprising forms. When scientists do not attend religious services they are more likely to accept the conflict paradigm. When scientists think their peers have a positive view of religion, they are less likely to agree there is a conflict between science and religion. Religious upbringing is associated with scientists adopting the conflict paradigm. Spirituality is much more important in this population than other research would lead us to believe. Results reformulate widely cited earlier research, offer new insights about how scientists view the connection between religion and science, and expand public discussion about religious challenges to science.     

Stimulant Treatment Reduces Lapses in Attention among Children with ADHD: The Effects of Methylphenidate on Intra-Individual Response Time Distributions

Recent research has suggested that intra-individual variability in reaction time (RT) distributions of children with ADHD is characterized by a particularly large rightward skew that may reflect lapses in attention. The purpose of the study was to provide the first randomized, placebo-controlled test of the effects of the stimulant methylphenidate (MPH) on this tail and other RT distribution characteristics. Participants were 49 9- to 12-year-old children with ADHD. Children participated in a 3-day double-blind, placebo-controlled medication assessment during which they received long-acting MPH (Concerta®), with the nearest equivalents of 0.3 and 0.6 mg/kg t.i.d. immediate-release MPH. Children completed a simple two-choice speeded discrimination task on and off of medication. Mode RT and deviation from the mode were used to examine the peak and skew, respectively, of RT distributions. MPH significantly reduced the peak and skew of RT distributions. Importantly, the two medication effects were uncorrelated suggesting that MPH works to improve both the speed and variability in responding. The improvement in variability with stimulant treatment is interpreted as a reduction in lapses in attention. This, in turn, may reflect stimulant enhancement of self-regulatory processes theorized to be at the core of ADHD.