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571.
O Diaz-Ruiz Y Zhang L Shan N Malik AF Hoffman B Ladenheim JL Cadet CR Lupica A Tagliaferro A Brusco CM Bäckman 《Learning & memory (Cold Spring Harbor, N.Y.)》2012,19(8):341-350
In the present study, we analyzed mice with a targeted deletion of β-catenin in DA neurons (DA-βcat KO mice) to address the functional significance of this molecule in the shaping of synaptic responses associated with motor learning and following exposure to drugs of abuse. Relative to controls, DA-βcat KO mice showed significant deficits in their ability to form long-term memories and displayed reduced expression of methamphetamine-induced behavioral sensitization after subsequent challenge doses with this drug, suggesting that motor learning and drug-induced learning plasticity are altered in these mice. Morphological analyses showed no changes in the number or distribution of tyrosine hydroxylase-labeled neurons in the ventral midbrain. While electrochemical measurements in the striatum determined no changes in acute DA release and uptake, a small but significant decrease in DA release was detected in mutant animals after prolonged repetitive stimulation, suggesting a possible deficit in the DA neurotransmitter vesicle reserve pool. However, electron microscopy analyses did not reveal significant differences in the content of synaptic vesicles per terminal, and striatal DA levels were unchanged in DA-βcat KO animals. In contrast, striatal mRNA levels for several markers known to regulate synaptic plasticity and DA neurotransmission were altered in DA-βcat KO mice. This study demonstrates that ablation of β-catenin in DA neurons leads to alterations of motor and reward-associated memories and to adaptations of the DA neurotransmitter system and suggests that β-catenin signaling in DA neurons is required to facilitate the synaptic remodeling underlying the consolidation of long-term memories. 相似文献
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Abufazel Hosseininasab Donald J. Viglione Joni L. Mihura Ety Berant Ana Cristina Resende 《Journal of personality assessment》2019,101(2):199-212
Controlling the number of Rorschach responses (R) as a method to reduce variability in the length of records has stimulated controversy among researchers for many years. Recently, the Rorschach Performance Assessment System (R–PAS; Meyer, Viglione, Mihura, Erard, &; Erdberg, 2011) introduced an R-Optimized method to reduce variability in R. Using 4 published and 2 previously unpublished studies (N = 713), we examine the extent to which 51 Comprehensive System–based scores on the R–PAS profile pages are affected as a result of receiving Comprehensive System (CS; Exner, 2003) administration versus a version of R-Optimized administration. As hypothesized, R—the intended target of R-Optimized administration—showed reliable weighted average differences across each method of administration. As expected, its mean modestly increased and its standard deviation notably decreased. Also as hypothesized, the next largest effects were decreases in the variability (SD) of 2 variables directly related to R, R8910% and Complexity. No other reliable differences were observed. Therefore, because R-Optimized administration does not notably modify the existing CS-based normative values for other profiled R–PAS variables, the data do not support concerns that R-Optimized administration notably modifies the Rorschach task or that existing CS research data would not generalize to R–PAS. However, because R-Optimized administration reduces variability in R, it allows a single set of norms to apply readily to more people. 相似文献
575.
Laura M. Simonds James D. Demetre Cristina Read 《The British journal of developmental psychology》2009,27(2):457-471
Despite the obvious phenomenological similarities between magical thinking and obsessive‐compulsiveness, the relationship between them has been the subject of few empirical investigations in samples of children. The present study aimed to examine the relationship between a general epistemic stance towards magical causation and tendencies towards obsessive‐compulsiveness in a non‐clinical sample of schoolchildren. One‐hundred and two children, aged between 5 and 10 years (48 boys and 54 girls), completed questionnaire measures designed to assess magical thinking, obsessive‐compulsiveness, and other forms of anxiety. School teachers completed a measure of strengths and difficulties for each child. General belief in magical causation was correlated with all types of anxiety, not just obsessive‐compulsiveness, with significant correlations shown for boys in the sample, but not girls. General belief in magical causation contributed little to the prediction of obsessive‐compulsiveness beyond general anxiety. In this study, a general epistemic stance towards magical causation did not differentiate obsessive‐compulsiveness from other anxiety dimensions. The findings are considered in the context of developmental theories of magical and scientific causal reasoning. 相似文献
576.
Cristina Colonnesi Geert Jan J.M. Stams Irene Koster Marc J. Noom 《Developmental Review》2010,30(4):352-366
The use of the pointing gesture is one of the first ways to communicate with the world. This gesture emerges before the second year of life and it is assumed to be the first form of intentional communication. This meta-analysis examined the concurrent and longitudinal relation between pointing and the emergence of language. Twenty-five studies were included into the meta-analysis, including 734 children. The role of several moderators was examined: pointing modality, pointing motive, age at which the pointing was measured, the assessment method of the pointing gesture and language development, the modality of language, SES, and country. The results showed both a concurrent (r = .52) and a longitudinal (r = .35) relation between pointing and language development. The relation between pointing and language development became stronger with age, and was found for pointing with a declarative and general motive, but not for pointing with an imperative motive. It is concluded that the pointing gesture is a key joint-attention behavior involved in the acquisition of language. 相似文献
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Stephen A. Woods Sara Ahmed Ioannis Nikolaou Ana Cristina Costa Neil R. Anderson 《European Journal of Work and Organizational Psychology》2020,29(1):64-77
ABSTRACTWe present a targeted review of recent developments and advances in digital selection procedures (DSPs) with particular attention to advances in internet-based techniques. By reviewing the emergence of DSPs in selection research and practice, we highlight five main categories of methods (online applications, online psychometric testing, digital interviews, gamified assessment and social media). We discuss the evidence base for each of these DSP groups, focusing on construct and criterion validity, and applicant reactions to their use in organizations. Based on the findings of our review, we present a critique of the evidence base for DSPs in industrial, work and organizational psychology and set out an agenda for advancing research. We identify pressing gaps in our understanding of DSPs, and ten key questions to be answered. Given that DSPs are likely to depart further from traditional non-digital selection procedures in the future, a theme in this agenda is the need to establish a distinct and specific literature on DSPs, and to do so at a pace that reflects the speed of the underlying technological advancement. In concluding, we, therefore, issue a call to action for selection researchers in work and organizational psychology to commence a new and rigorous multidisciplinary programme of scientific study of DSPs. 相似文献
579.
Cristina Sanches Maria Gouveia-Pereira Felice Carugati 《The British journal of educational psychology》2012,82(4):606-621
Background. The current paper is based on two different approaches. One is the relational model of authority (Tyler & Lind, 1992), which addresses the effects of justice perceptions on the legitimacy of authorities and behavioural compliance. The other is Emler and Reicher's theory (1995, 2005), which explains the involvement of adolescents in delinquency through their relationship with the institutional authorities of society. Aims. To provide empirical evidence for the linkage of these perspectives, analysing the relationship between justice perceptions about teachers and the involvement of adolescents in deviant behaviour. Our hypotheses are that teachers’ justice is negatively related with deviant behaviour and that this relationship is mediated through the evaluation of institutional authorities, after controlling for school failure. Sample. Three hundred and ninety adolescents aged between 14 and 17 years. Methods. Participants completed the following scales: perceptions of justice about teachers, evaluation of institutional authorities, and deviant behaviour. Data were examined through correlation and bootstrap analyses. Results. Justice judgments about teachers were negatively related with deviant behaviour, and this relationship was partially mediated by the evaluation of institutional authorities, even after controlling for school failure. However, procedural justice revealed a much stronger relationship with deviance, compared to distributive justice. Conclusions. As predicted, these results suggest that when adolescents perceive school authorities as fair, other institutional authorities are likely to be perceived in a similar way and the more those authorities are positively evaluated, the less often adolescents engage in deviant conduct. Results are discussed according to the theories underlying our hypothesis. Directions for future research are suggested. 相似文献
580.