早产儿预防性应用抗生素的临床决策思路

近年来,随着对滥用抗生素所引起的细菌耐药性和二重感染的认识的逐步深入,预防性应用抗生素在临床上越来越受到限制。但由于早产儿感染的临床隐匿性和易并发严重并发症等特点,预防早产儿感染的发生和进一步的发展,就显得尤为重要。通过对早产儿发生感染的易感因素、感染诱因和临床特点的分析研究,来探讨早产儿临床预防应用抗生素的必要性、合理性及临床决策思路。     

制造行业管理胜任力与绩效关系的实证研究

通过对571名制造型企业管理者的问卷调查,探索并验证了制造业管理胜任力结构维度,检验了不同背景因素对管理胜任力的影响。结果表明:制造业管理胜任力具有六维结构,包含22个指标,其信度和效度较好;不同管理层次的管理者在制造过程控制和市场营销策划维度上的评价有显著性差异,不同企业规模下的管理者在行业核心理念和产品系统管理维度上的评价有显著性差异;产品系统管理与市场营销策划能力对制造业管理者绩效有良好的预测力。同时发现,制造业管理胜任力不能较好地解释周边绩效的变异量。     

结果预期对青少年攻击性行为的影响：中介效应与调节效应

采用攻击性问卷、关系攻击行为量表、结果预期量表、移情量表和自我控制能力问卷对720名中学生进行调查,考察了结果预期与青少年攻击性行为的关系,以及自我控制在其中的中介作用和移情在其中的调节作用。结果发现:(1)结果预期与青少年的攻击性行为(外部攻击和关系攻击)存在显著负相关;(2)自我控制在结果预期与青少年攻击性行为之间起着完全中介作用;(3)在结果预期对青少年外部攻击行为的预测中,移情发挥了调节作用。在高移情个体中,结果预期并不预测外部攻击行为,而在低移情个体中,结果预期显著地反向预测外部攻击行为;(4)自我控制在结果预期与青少年外部攻击行为之间的中介作用受到移情的调节,高水平的移情能力可以有效地缓解青少年因低自我控制而导致的高攻击性。     

Development and analysis of a community-based resource recovery program

Five studies were conducted over a 10-month period to determine the effectiveness of specific procedures in encouraging recycling among residential neighborhoods. Results indicated that: (a) initial levels of participation in neighborhoods were frequently related to housing values; (b) weekly recycling pick-ups that coincided with garbage collection days resulted in higher levels of participation than pick-ups that occurred at other times; (c) notifying homes about the recycling program through distributed door-to-door brochures was more effective than soliciting participation through newspaper ads; (d) distributing containers to help residents separate recyclable from nonrecyclable material proved to be an effective procedure, especially when combined with frequent prompting (prompting alone did not have much effect); and (e) procedures that facilitated the greatest levels of participation were not always cost-effective. The subsequent combination of these procedures into a package program resulted in high levels of neighborhood participation that were cost-effective and maintained over a 6-month period.     

Memory deficits in compulsive checkers: replication and extension in a clinical sample

Thirteen checkers and twelve noncheckers, identified on the basis of their responses to the checking subscale of the Maudsley Obsessional-Compulsive Inventory (MOCI; Rachman and Hodgson, 1980), were recruited from a sample of 99 consecutive admissions to the outpatient department of a community mental health center. Consistent with our previous research with nonclinical samples of college students (Sher et al., 1983, 1984), checkers were found to show deficits in memory, especially recall for recently completed actions, compared to noncheckers. This result demonstrates the replicability of our previous findings across different types of samples and implicates deficits in memory for actions as a potentially important determinant of checking behavior. Assessment of spontaneous imagery associated with the anamnestic process suggested that checkers utilized less imagery, especially visual imagery, when recalling biographical information. Additional measures collected at the time of testing indicated that checkers were more neurotic and reported more psychological distress than noncheckers.     

医疗人工智能产品研发的伦理审查与法律考量

国内医疗人工智能研究日益增多,具有多学科合作,并以数据驱动的特点。走访深圳开展健康领域人工智能研发的企业、医疗机构以及研究机构的开发者,了解到存在监管不足、数据收集及处理过程欠缺标准化、责任不清等挑战。并且,面临应该如何遵循医学科研伦理审查原则,如何合法合规收集、利用、共享数据并界定责任等问题。从医院进行伦理审查实践层面探讨医疗人工智能的研究价值、科学有效性、风险受益等的审查要点;医疗人工智能研究的法律考量主要包括个人信息收集和利用的边界,以及侵权责任主体的认定。     

DRD2基因TaqIA多态性与同伴侵害对青少年早期抑郁的交互作用

本研究运用问卷法与DNA分型技术,对1063名青少年(初次测评年龄为12.32±0.47岁,50.3%女生)进行间隔2年的追踪调查,考察DRD2基因TaqIA多态性与同伴身体侵害和关系侵害对青少年早期抑郁的交互作用及其性别差异。结果发现,TaqIA多态性与身体侵害、关系侵害均对男青少年抑郁存在显著的交互作用。在携带A2A2基因型的男生中,身体侵害和关系侵害可以显著正向预测其抑郁水平,而在携带A1等位基因的男生中,同伴侵害对抑郁无预测作用。此外,TaqIA多态性与身体侵害、关系侵害对女生抑郁均无显著交互作用。研究结果提示,同伴侵害是一种重要的候选环境指标,与TaqIA多态性交互影响青少年早期抑郁,并且性别在这一基因×环境交互作用中起到重要的调节效应。     

早产儿预防性应用抗生素的临床决策思路

近年来,随着对滥用抗生素所引起的细菌耐药性和二重感染的认识的逐步深入,预防性应用抗生素在临床上越来越受到限制.但由于早产儿感染的临床隐匿性和易并发严重并发症等特点,预防早产儿感染的发生和进一步的发展,就显得尤为重要.通过对早产儿发生感染的易感因素、感染诱因和临床特点的分析研究,来探讨早产儿临床预防应用抗生素的必要性、合理性及临床决策思路.     

父母心理控制与小学生的欺负行为:敌意归因和冷酷无情的作用检验

采用班级整群抽样法选取1847名3~6年级小学生（男生987名;平均年龄10.73±1.16岁）及其家长为被试,采用问卷法考察父母心理控制与小学生欺负行为的关系,同时探讨敌意归因和冷酷无情的中介作用。结果发现：（1）父母心理控制显著正向预测小学生的欺负行为;（2）冷酷无情在父母心理控制与小学生欺负行为间的关系中存在中介作用,敌意归因不发挥中介作用;（3）父母心理控制对小学生欺负行为影响的中介机制不存在显著的性别差异和学段差异。本研究结果表明,冷酷无情是父母心理控制影响小学生欺负行为的重要机制,但敌意归因不是。研究者和实践者应注重对欺负者情感加工能力的关注和干预。     

Heart rate and ratings of perceived exertion during treadmill and elliptical exercise training

Elliptical exercise has recently increased in popularity. However, little is known regarding heart rate and perceptual responses during this exercise mode even though such information is important with respect to prescribing and regulating exercise intensity. In the current study, heart rate and perceived exertion were compared between treadmill and elliptical exercise. During treadmill exercise (TM(EST)) participants estimated RPE-Overall as well as RPE-Legs and RPE-Chest. Two elliptical sessions followed: (1) RPE estimation during elliptical exercise (EL(EST)): HR (b/ min.) from TM(EST) was achieved during elliptical exercise, with participants estimating RPE-Overall, RPE-Legs, and RPE-Chest. (2) RPE production during elliptical exercise (EL(PROD)): RPE-Overall from TM(EST) was produced during elliptical exercise. There were no significant differences between modes for RPE-Overall (TM(EST): 11.2 +/- 2.2 vs EL(EST): 11.9 +/- 3.2) or RPE-Chest (TM(EST): 11.0 +/- 2.4 vs EL(EST): 11.7+/- 3.2). Mean RPE-Legs was significantly different (TM(EST): 11.2 +/- 2.4 vs EL(EST): 12.5 +/- 3.1). Heart rate was not significantly different between TM(EST) (163 +/- 16.6) and EL(PROD) (159 +/- 20.0). Analysis indicated elliptical exercise is perceived as more intense with respect to leg (RPE-Legs) exertion. Further, RPE-Overall appears effective for regulating heart rate during elliptical exercise.