The executive control of mnemonic activity

The present study focused on the executive monitoring of a rehearsal strategy by sixth (11 years 5 months), tenth (15 years 8 months), and twelfth (17 years 9 months) graders and adults (27 years 4 months). The results showed that all of the adults spontaneously adopted an “optimal” strategy and generalized it to a second task. However, none of the sixth graders and only two tenth and three twelfth graders did so. All of the school subjects subsequently trained to rehearse, maintained the strategy without prompting, and showed evidence of transfer. In comparison to adults, the trained subjects' generalized routines became more similar to the adults' as grade increased. This study supports the notion that efficient executive functioning includes the case where continued use of a mnemonic routine is a reasonable response to an objective change in an information-processing task.     

Manipulation of response-contingent unconditioned-stimulus intensity in human eyelid conditioning: A two-phase model analysis

Four groups of human subjects were given 360 classical eyeblink conditioning trials. All groups received the same UCS (unconditioned stimulus) intensity on[Formula: see text] (nonconditioned response) trials but differed in the intensity presented on CR trials. Response probability increased as a positive function of UCS intensity on CR trials. Phase 1 of the two-phase model was longer when no UCS was presented on CR trials, but did not differ in duration among the remaining three groups. Most subjects could be described with a single operator in Phase 2, the operator limit increasing as a positive function of CR-contingent UCS intensity. For subjects requiring different operator limits on CR and[Formula: see text] trials, the latter was lower with high CR-trial intensities but higher with low CR-trialintensities. The results were interpreted to be more consistent with drive theory than with "law-of-effect" or two-factor theories.     

Practice and training in bimanual coordination tasks: strategies and constraints.

There are a number of structural constraints on the coordination of the two hands. Understanding bimanual coordination involves not only identification of these constraints but also how they can be overcome or modulated. The performance of polyrhythms has been used to examine these issues. In this article the constraints on coordination are outlined and research on the acquisition of polyrhythms is reviewed. It is suggested that the constraints on the production of multifrequency ratios are overcome by integrating the timing of the two hands. Oscillator models of coordination are then considered and a two-process model of motor timing is suggested.     

Defensive burying, nest relocation, and pup transport in lactating female rats

A wire-wrapped wooden dowel was inserted through the wall of the nest compartment of a two-compartment box. There were four conditions. Some lactating female rats were shocked by the dowel when they first touched it, and some were not, after which the dowel was either immediately withdrawn from the chamber or left in place for the duration of the ensuing 30-min test period. Three defensive behaviours were observed during the tests: the mothers buried the shock source with bedding from the floor of the chamber, they transported their pups to the adjoining “safe” chamber, and they built a new nest in the safe chamber from material salvaged from their original nest. The shocked mothers that were confronted with the shock source throughout the test period displayed significantly more of each of these three defensive behaviours than did the mothers in the other three conditions. The methods used in this study provide a simple, reliable, safe paradigm for studying maternal defensive behaviour; the results indicate that the defensive capacities of the rat extend far beyond stereotypical flight, freeze, and fight responses, which have been the focus of most research on rodent defense.     

Understanding the Progression from Early Alcohol Use Experimentation to Alcohol Use Disorder: Testing Vulnerability by Experience Interactions Using a Two-Part Latent Growth Curve Model

Most adolescents experiment with alcohol, but a smaller percentage advance to heavy alcohol use (AU) and AU disorder (AUD). Understanding for whom and how early risk leads to AUD is of interest to prevention, treatment, and etiology of AUD. Informed by developmental and behavioral neuroscience theory, the current study tested whether temperament (effortful control, surgency, and negative affect), peer AU (multi-reporter), and AU with parents’ permission interacted to distinguish youth who experiment with alcohol from those who escalate to AUD. Community adolescents (N?=?765, 53% female) were assessed annually for seven years (M_age?=?11.8, range: 10–13 at Year 1; M_age?=?18.7; range?=?17–20 at year 7). Temperament by early experience interactions were expected to predict amount of AU. Amount of AU was expected to mediate the relationship between the interactions and AUD symptoms (assessed at Years 3 and 7, M_age?=?13.8 and 18.7) above and beyond a range of confounds (e.g., problem behavior and parental AU and AUD). Supporting hypotheses, effortful control and surgency interacted with AU with parents’ permission and peer AU, respectively, to predict higher amount of AU (R²?=?0.47) and AUD symptoms (R²?=?0.03). Results support developmental and behavioral neuroscience theory. High surgency and low effortful control in conjunction with peer AU and AU with parents’ permission were associated with large effects on AU and moderate mediated effects through AU to AUD. AU with parents’ permission was risky at low and high effortful control and protective when peers used alcohol.

     

To Be or Not: A Brief History of the Health Humanities Consortium

The Health Humanities Consortium (HHC) was established in 2015 to “promote health humanities scholarship, education, and practice through transdisciplinary methods and theories that focus on the intersection of the arts and humanities, health, illness, and healthcare.” As the founding co-chairs of the HHC, we provide a history of the founding of this organization in this article, describing the journey of its creation, the choices and challenges it faced as a new organization, and our hopes for a rich future.

     

Multiple sclerosis,emotion perception and social functioning

People with multiple sclerosis (MS) can experience problems in interpreting others’ emotions from faces or voices. However, to date little is known about whether difficulties in emotion perception in MS are related to broader aspects of social functioning. Also, there are few studies reporting the effect of MS on more ecologically valid assessments of emotion perception using multimodal videos. The current study looks at (1) the effect of MS on perceiving emotions from faces, voices and multimodal videos; (2) the possible role of slowed processing and executive dysfunction in emotion perception problems in MS and (3) the relationship between emotion perception and broader social functioning in MS. 53 people with MS and 31 healthy controls completed tasks of emotion perception and cognition, and assessed their levels of social support and social participation. Participants with MS performed worse than demographically matched controls on all measures of emotion perception. Emotion perception performance was related to cognitive measures in those with MS. Also, significant associations were found between emotion perception difficulties in MS and poorer social function. In particular, people with MS who had poorer emotion perception also reported lower levels of social support from their friends, and regression analysis showed that this prediction was maintained even when disease severity and cognitive function were taken into account. These results show that problems with emotion perception in MS extend to more realistic tasks and may predict key aspects of social functioning.     

Re-exposure to reinforcement in Context A during treatment in Context B reduces ABC renewal

Previous work from our laboratory showed that intermittently re-exposing rats to reinforcement for lever pressing in a training (A) context, while eliminating lever pressing in a second (B) context, increased ABA renewal of lever pressing relative to rats that experienced only Context B during response elimination. In the current study, we replicated these procedures while assessing renewal in the presence of a novel context (i.e., ABC renewal). Unlike the findings described above, renewal was reduced in the group that experienced re-exposure to Context A during lever-press elimination relative to rats that experienced only Context B. These findings suggest that alternating between contexts associated with reinforcement and extinction during treatment reduces the probability that organisms will respond in novel contexts. These outcomes may be the result of discrimination and/or generalization processes. Moreover, this training procedure may offer a potential mitigation strategy for ABC renewal.     

Aggression-consistent, -inconsistent,and -irrelevant priming effects on selective exposure to media violence

Priming with aggressive concepts increases males' attraction to media violence. It was hypothesized that priming with schema-irrelevant concepts would decrease interest relative to the effects of schema-relevant concepts, whether or not the schema-relevant concepts were also schema-consistent. Thirty male undergraduates used lists including aggressive (schema-consistent and schema-relevant), positive or prosocial (schema-inconsistent yet relevant), or entirely neutral (schema-irrelevant) words to write short stories (priming task), then received an opportunity to select videotaped film clips for viewing. Subjects primed by aggressive word lists included more aggression, anger, fear, and violence in their stories than did those in the aggression-inconsistent and aggression-irrelevant conditions, whereas aggression-inconsistent priming yielded more fun, helping, and joy than did other conditions. Aggressively primed subjects expressed more interest in films containing violence and hostility than did neutrally primed subjects, whereas aggression-inconsistent priming did not differ significantly from either aggressive (schema-consistent) or neutral (schema-irrelevant) priming. Findings indicate that the aggressive priming activates aggressive concepts that make violence and hostility more salient to individuals. Because male undergraduates typically express interest in violence, enhanced salience leads to increased interest. © 1992 Wiley-Liss, Inc.