Hippocampal extracellular acetylcholine (ACh) and choline levels were evaluated using in vivo microdialysis in male Fischer 344 rats before, during, and following an 80-min exposure to two different stress conditions. Measurements were taken in rats restrained and immersed in a water bath containing either 37 degreesC (normothermic-restraint) or 20 degreesC (cold-restraint) water. Results were compared to normothermic-freely-moving rats. Cold-restrained rats displayed decreased ACh levels during cold exposure relative to both normothermic-restrained and normothermic-freely-moving rats. By the end of the cold exposure period and following removal from cold, ACh levels had returned to near-baseline values. Normothermic-restrained rats had levels similar to those of normothermic-freely-moving rats, except for a marked increase in ACh following removal from restraint. Cold-restrained rats displayed a gradual elevation in choline levels during cold stress, followed by a gradual decline after stress termination, whereas both normothermic-restrained and normothermic-freely-moving rats displayed gradual decreases during the microdialysis session. These findings demonstrate that central cholinergic neurotransmission can be altered by the application of, and removal from, acute stressors. In addition, the results suggest a possible relationship between the magnitudes of both the stressor and its cholinergic consequences. 相似文献
Final-year nursing students (N= 96) described their anxieties about biohazards, not only in relation to the occupational context of a hospital ward, but also in relation to their general life context. These contexts were reported to vary in the extent to which they permitted control over exposure to the two particular biohazards chosen for study: human immunodeficiency virus (HIV) and hepatitis B virus (HBV). The data showed that nurses' anxiety about contracting HIV infection varied significantly across the two contexts, while anxiety about contracting HBV infection did not. In the general life context, anxiety about HIV was greater than anxiety about HBV for all subjects. This difference was significantly greater for those with incorrect knowledge about objective HIV seroconversion rates than for those with correct knowledge. 相似文献
The adolescent substance abuser, like adult addicts, is most commonly considered from the perspective of the disease model. The usefulness of the disease model in conceptualizing adolescent substance abuse is questioned, and an alternative view of the topic is set forth. Substance abuse, is regarded as an adaptive aspect of the ongoing interactive processes within the family. The developmental process of the adolescent substance abuser is seen as a functional dynamic in the family's preservation. Three characteristic elements of parental interaction common to the development of adolescent substance abuse are highlighted.An earlier version of this paper was presented at the Texas Association for Marriage and Family Therapy annual conference on January 28, 1993 in Houston Texas.a research associate and director of the Don D. Jackson Archive at the Mental Research Institute, Palo Alto, CA. Authors are listed alphabetically. 相似文献
College students ( n = 197) voted to select a beauty queen from among six photographs equivalent in physical attractiveness, as determined by rankings of 35 students from a separate university. Half the photographs bore a desirable first-name and half were assigned an undesirable first-name. As predicted, firstname had a significant effect on physical attraction: Girls with desirable firstnames received 158 votes to 39 for those with undesirable names. These data were discussed in terms of an additive, rather than an interactive, effect, due to the nature of the task. The strength of these findings was related to the study's ecological validity. 相似文献
Health and salvation are related terms, because each seeks the well-being of the whole person. When placed within the Judeo-Christian context, health as salvation can be defined as the highest good for the total human community. This good is denied to humanity through the unequal use of the world's resources, a fact underscored by the current energy crisis. Two questions must be answered: 1) Do we possess the scientific means to rectify this ethically unacceptable situation? 2) Do we desire to implement the necessary steps to change, should they be found? 相似文献
The progress of two therapy groups for university students is described. Some difficulties were encountered in their organisation and in the selection of group members. There were also problems regarding confidentiality. On the other hand, the closure of one group during the university vacations did not impede its progress. Such group therapy seemed particularly suitable for students with less severe psychiatric disturbance and for those with adolescent difficulties in separation and individuation. Students with more severe personality disorder or those with a recent history of serious mental illness progressed less satisfactorily. 相似文献
The study examined the interactive effects of degree of biculturalism and locus of control on leader behavior in supportive and nonsupportive ethnically mixed small groups. Subjects were 36 male Chicano college students who participated in a small group discussion composed of four members: a naive subject who invariably served as group leader, and three confederates representing distinct ethnic groups (Anglo, Black, and Chicano). Behavioral observations revealed several interesting interactions involving group support. High biculturals, in comparison to low biculturals, adopted a more active leader role in nonsupportive than in supportive groups, asking for more opinions and evaluations, and making more clarification statements. Furthermore, while low bicultural externals and high bicultural internals tended to be more interpersonally assertive and to make more clarification statements under supportive conditions, it was low bicultural internals and high bicultural externals who exhibited the most active leader roles in nonsupportive groups. Additional findings revealed that statements made by the Anglo confederate were clarified more often in the supportive condition, while statements made by either the Black or the Chicano confederate were clarified more often in the nonsupportive condition. The results are discussed in relation to previous literature and the need to develop a more responsive social psychology of interethnic dynamics. 相似文献
Novak, Jones, and Jones (1975) state that menstrual distress (dysmenorrhea) is the greatest cause of lost work hours among women, and Kistner (1970) estimate this to be 140 million annual work hours. Thirty-five percent of female adolescents. 25% of college women, and 60–70% of single females in their 30's and 40's are said to be invalid during menstruation (Green, 1971). Treatment procedures for primary dysmenorrhea have included hypnosis (Lackie, 1964), physical exercises (Golub. 1959). natural childbirth techniques (House, 1969), and oral contraceptives.
Though hormones are the most recent, frequent and effective treatment approach (Novak et al. 1975). Tyler (1973) cautions against their use because of possible adverse side effects. Recently, systematic desensitization (SD) has been used to relieve menstrual distress (Mullen, 1968, 1971; Reich, 1972; Tasto and Chesney, 1974) without risk of such side effects. Although SD has been effective, considerable response variability has been noted.
Becuase of this variability. Chesney and Tasto (1975a) developed the Menstrual Symptom Questionnaire (MSQ) to psychometrically identify two types of primary dysmenorrhea: spasdomic dysmenorrhea which designates distress during the flow period associated with excessive muscle tension, and congestive dysmenorrhea referring to premenstrual tension related to water retention. This instrument was designed to define types of menstrual symptoms and not symptom severity. Test-retest reliability was 0.87 and discrimination between spasdomic and congestive dysmenorrhea was highly significant. Of 48 women tested. 29 were identified as spasdomic with MSQ scores between 82 and 102, while 19 scored in the congestive range (46–68). Interestingly, no women scored in the median range (69–81), suggesting that there exists two unique types of primary dysmenorrhea identifiable by the MSQ. Subsequently, Chesney and Tasto (1975b) reported that congestive women did not respond to SD, while spasdomic symptoms were significantly reduced. It was hypothesized that the relaxation training component of SD was effective with spasmodic muscle tension symptoms and ineffective with congestive water retention symptoms. Consequently, the MSQ was thought capable of accounting for previously reported response variability of primary dysmenorrhea to SD.
The present study was intended to replicate Chesney and Tasto's (1975a, 1975b) findings. The following Null hypotheses were tested; (a) the MSQ does not have significant test-retest reliability; (b) the congestive-spasmodic symptom dimension of the MSQ is not dichotomous; and (c) the MSQ does not predict SD effectiveness 相似文献