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31.
According to a traditional assumption about working memory, participants retain a series of verbal items for immediate recall
using covert verbal rehearsal, without much need for attention. We reassessed this assumption by imposing a speeded, nonverbal
choice reaction time (CRT) task following the presentation of each digit in a list to be recalled. When the memory load surpassed
a few items, performance on the speeded CRT task became increasingly impaired. This CRT task impairment depended only on attention-related
components of working memory; it was not alleviated by the presence of an auditory memory trace that automatically helped
the recall of items at the ends of spoken lists. We suggest that attention-demanding refreshing of verbal stimuli occurs along
with any covert rehearsal. 相似文献
32.
Impairment on standard tests of delayed recall is often already maximal in the aMCI stage of Alzheimer's Disease. Neuropathological work shows that the neural substrates of memory function continue to deteriorate throughout the progression of the disease, hinting that further changes in memory performance could be tracked by a more sensitive test of delayed recall. Recent work shows that retention in aMCI patients can be raised well above floor when the delay period is devoid of further material - 'Minimal Interference'. This memory enhancement is thought to be the result of improved memory consolidation. Here we used the minimal interference/interference paradigm (word list retention following 10 min of quiet resting vs. picture naming) in a group of 17 AD patients, 25 aMCI patients and 25 controls. We found (1) that retention can be improved significantly by minimal interference in patients with aMCI and patients with mild to moderate AD; (2) that the minimal interference paradigm is sensitive to decline in memory function with disease severity, even when performance on standard tests has reached floor; and (3) that this paradigm can differentiate well (80% sensitivity and 100% specificity) between aMCI patients who progress and do not progress to AD within 2 years. Our findings support the notion that the early memory dysfunction in AD is associated with an increased susceptibility to memory interference and are suggestive of a gradual decline in consolidation capacity with disease progression. 相似文献
33.
We examined predictors and outcomes of women's hostility toward other women. Based on a projection model, we hypothesized and tested the theory via structural equation modeling that women's sense of personal inadequacy, the tendency to stereotype, and general anger would predict hostility toward women, and hostility toward women would predict blaming victims of violence and poor relationships with a female friend. Participants were 464 college women with an average age of 28.08. All measures were pencil and paper. Women's hostility toward women served as an intervening variable between a personal sense of inadequacy, tendency to stereotype, blaming women victims of violence, and intimacy with one's best female friend. 相似文献
34.
Robert Cowan 《Philosophy and phenomenological research》2015,90(1):164-193
In the recent metaethical literature there has been significant interest in the prospects for what I am denoting ‘Perceptual Intuitionism’: the view that normal ethical agents can and do have non‐inferential justification for first‐order ethical beliefs by having ethical perceptual experiences, e.g., Cullison 2010, McBrayer 2010, Vayrynen 2008. If true, it promises to constitute an independent a posteriori intuitionist epistemology, providing an alternative to intuitionist accounts which posit a priori intuition and/or emotion as sources of non‐inferentially justified ethical beliefs. As it is formulated, it is plausible that a necessary condition for the view is the truth of Ethical Perception: normal ethical agents can and do have perceptual experiences (at least some of which are veridical) as of the instantiation of ethical properties. In this paper a sophisticated and promising account of Ethical Perception is offered. Extant objections are shown to fail. However, it will be argued that it is far from obvious that the account of Perceptual Intuitionism which emerges constitutes an independent alternative to other intuitionist accounts. This is because we have reason to think that ethical perceptual experience may be epistemically dependent on other epistemic sources, e.g. a priori intuition or emotion. 相似文献
35.
Emma H. Moscardini;Thanh P. Le;Tovah Cowan;Jessica Gerner;Anthony Robinson;Alex S. Cohen;Raymond P. Tucker; 《Suicide & life-threatening behavior》2024,54(1):61-69
The Virtual Hope Box (VHB) is a smartphone application designed to support emotion regulation when one is distressed, in a crisis, or experiencing suicidal ideation (SI). Initial proof of concept studies indicate that individuals are more likely to use the VHB than traditional hope boxes, and find it both easy to setup and helpful. To our knowledge, no studies have harnessed ambulatory assessment methodology to assess VHB use as it relates to incidence of suicidal thinking. 相似文献
36.
Stephen Rhodes Nelson Cowan 《British journal of psychology (London, England : 1953)》2019,110(2):449-460
This special issue of the British Journal of Psychology brings together cutting edge research on a range of topics in visual working memory (VWM). In this commentary, we attempt to summarize common themes in current VWM research exemplified in this issue. The articles include several reviews of important topics as well as empirical papers covering three main themes. The first concerns the nature of mental representations of memoranda in the commonly used delayed estimation task, where both fine‐grained and broad categorical details appear to be represented, and their susceptibility to interference. The second concerns interactions between VWM representations, both those that produce individuation of representations and those that create an overarching ensemble structure. Finally, the third main topic concerns the use of VWM during visual search and in the learning of repeated configurations in search displays. The work presented here, and other work in the field, points to a rich interplay between representations in VWM but also between VWM and information in long‐term memory. Opportunities for further investigation are highlighted throughout. 相似文献
37.
Presentation of two kinds of materials in working memory (visual and acoustic), with the requirement to attend to one or both modalities, poses an interesting case for working memory development because competing predictions can be formulated. In two experiments, we assessed such predictions with children 7–13 years old and adults. With development, the ability to hold more information in the focus of attention could lead to an increase in the size of the trade‐off between modalities; if attention can hold A items during unimodal‐attention trials, then on average attention should hold A/2 of those same items during bimodal‐attention trials. If A increases with age, so would the dual‐task cost, A/2. The results clearly ruled out that possibility. It was the modality‐ or code‐specific components of working memory that improved with age and not the central component. We discuss various mechanisms that could have produced these results, including alternative attention‐based mechanisms. The findings point to a rich field for continued research. 相似文献
38.
Emily T. Cowan Anli A. Liu Simon Henin Sanjeev Kothare Orrin Devinsky Lila Davachi 《Learning & memory (Cold Spring Harbor, N.Y.)》2021,28(9):329
Research has shown that sleep is beneficial for the long-term retention of memories. According to theories of memory consolidation, memories are gradually reorganized, becoming supported by widespread, distributed cortical networks, particularly during postencoding periods of sleep. However, the effects of sleep on the organization of memories in the hippocampus itself remains less clear. In a 3-d study, participants encoded separate lists of word–image pairs differing in their opportunity for sleep-dependent consolidation. Pairs were initially studied either before or after an overnight sleep period, and were then restudied in a functional magnetic resonance imaging (fMRI) scan session. We used multivariate pattern similarity analyses to examine fine-grained effects of consolidation on memory representations in the hippocampus. We provide evidence for a dissociation along the long axis of the hippocampus that emerges with consolidation, such that representational patterns for object–word memories initially formed prior to sleep become differentiated in anterior hippocampus and more similar, or overlapping, in posterior hippocampus. Differentiation in anterior hippocampal representations correlated with subsequent behavioral performance. Furthermore, representational overlap in posterior hippocampus correlated with the duration of intervening slow wave sleep. Together, these results demonstrate that sleep-dependent consolidation promotes the reorganization of memory traces along the long axis of the hippocampus.The hippocampus has long been considered critical for encoding new memories; however, the effects of consolidation on hippocampal memory traces has remained an area of active research. Memories are thought to be stabilized for the long term as they become distributed across neocortical networks (Buzsáki 1989; Alvarez and Squire 1994; McClelland et al. 1995), a process supported by mechanisms during sleep (Diekelmann and Born 2010; Rasch and Born 2013). Whereas much research has been devoted to understanding the hippocampal contributions to the long-term retention of memories, open questions remain in considering how sleep-dependent consolidation affects the organization of hippocampal traces.The hippocampus has previously been shown to be critical for binding disparate elements of an experience together (Cohen and Eichenbaum 1993; Davachi 2006). Theories suggest that the hippocampus quickly encodes new experiences, while the cortex, with a slower learning rate, gradually comes to represent the central features from this hippocampal trace, resulting in abstracted memories that can be integrated into long-term cortical stores (McClelland et al. 1995). Prior research has demonstrated evidence for a coordinated hippocampal–cortical dialogue during sleep (Andrade et al. 2011; Bergmann et al. 2012; Ngo et al. 2020) as well as enhanced hippocampal–cortical functional connectivity after learning, facilitating the retention of memories (Tambini et al. 2010; Tompary et al. 2015; Murty et al. 2017; Cowan et al. 2021). Reports suggest consolidation results in more integrated cortical memory traces in the cortex (Richards et al. 2014; Tompary and Davachi 2017; Cowan et al. 2020); however, it remains an open question whether the active consolidation processes that support memory reorganization across hippocampal–cortical networks also transform hippocampal memory traces.Research on the fate of the hippocampal trace with consolidation has often focused on questions about the permanence of memories in the hippocampus. Theories of systems consolidation have classically debated whether the hippocampal trace is time-limited (Alvarez and Squire 1994), or, rather, whether the hippocampus continues to represent memories in perpetuity (Nadel and Moscovitch 1997; Winocur and Moscovitch 2011; Moscovitch et al. 2016; Sekeres et al. 2018a). Another theory posits that while the original hippocampal trace is transient, during retrieval the hippocampus reconstructs details of an experience from cortical traces (Barry and Maguire 2019). Much research in this vein has focused on investigating changes in hippocampal blood-oxygenation level-dependent (BOLD) univariate activation with time (Bosshardt et al. 2005a,b; Takashima et al. 2006, 2009; Gais et al. 2007; Sterpenich et al. 2007, 2009; Yamashita et al. 2009; Milton et al. 2011; Watanabe et al. 2012; Ritchey et al. 2015; Baran et al. 2016; Dandolo and Schwabe 2018) and the effects of hippocampal lesions in animals and humans (Winocur et al. 2001; Frankland and Bontempi 2005; Winocur and Moscovitch 2011; Moscovitch et al. 2016) with mixed results. Interestingly, pinpointing these effects along the long axis of the hippocampus has also proven unclear. Some reports have found that only the anterior hippocampus exhibits time-dependent changes in retrieval-related univariate activation, with evidence of decreases with delay (Takashima et al. 2006; Milton et al. 2011; Dandolo and Schwabe 2018), but also evidence of greater activation for more remote, compared with recent, memories (Bosshardt et al. 2005a,b). At the same time, other studies have found decreases in univariate activation only in the posterior hippocampus (Bosshardt et al. 2005b; Takashima et al. 2009; Yamashita et al. 2009; Milton et al. 2011; Watanabe et al. 2012; Ritchey et al. 2015; Sekeres et al. 2018b).Because of these conflicting findings, instead of asking just about dependence or overall changes in activation in the hippocampus, theories and empirical research have instead increasingly considered the organization of memory representations in the hippocampus (Robin and Moscovitch 2017; Sekeres et al. 2018a). Broadly, using representational similarity analyses, several studies have shown that hippocampal memory representations tend to become differentiated over learning, particularly for memories with overlapping content (LaRocque et al. 2013; Schlichting et al. 2015; Chanales et al. 2017; Brunec et al. 2020). Furthermore, it has been suggested that information is represented at different scales or “granularity” along the long axis of the hippocampus, in line with place field size differences (Kjelstrup et al. 2008; Komorowski et al. 2013), with anterior hippocampus representing more similar, coarse-grained, or gist-like information, while the posterior hippocampus represents fine-grained, detail-oriented representations (Evensmoen et al. 2013; Poppenk et al. 2013; Robin and Moscovitch 2017; Brunec et al. 2018, 2020). However, limited work has investigated whether this representational organization is altered with consolidation. Reports have shown that memory representations sharing overlapping content become more similar over a delay (Tompary and Davachi 2017; Audrain and McAndrews 2020), yet other work has found that hippocampal representations were not modulated by time (Ritchey et al. 2015; Ezzyat et al. 2018). Intriguingly, reports indicating greater differentiation in memories in anterior compared with posterior hippocampus with consolidation (Tompary and Davachi 2017; Dandolo and Schwabe 2018; Ezzyat et al. 2018) raise the possibility that the representational granularity along the anteroposterior axis may be transformed with consolidation. Thus, more work is needed to understand how consolidation influences the representational structure of memories in the hippocampus. In particular, despite much research connecting sleep to consolidation (Diekelmann and Born 2010; Rasch and Born 2013), it remains unknown whether sleep-dependent processes facilitate such delay-dependent transformations to the hippocampus.Active processes in the sleeping brain seem to be optimized for systems consolidation. Currently, the best mechanistic evidence for sleep-dependent consolidation comes from studies on hippocampal replay showing the repeated reactivation of encoding-related patterns of hippocampal activity (Buzsáki 1989; Wilson and McNaughton 1994; Girardeau and Zugaro 2011), which seems to be coordinated with replay in areas of the cortex (Ji and Wilson 2007; Peyrache et al. 2009; Wierzynski et al. 2009). It is thought that the coupling between oscillations during non-REM sleep stages (particularly slow wave sleep [SWS])—including sharp wave ripples that support replay, thalamocortical spindles, and slow oscillations—facilitates the hippocampal–cortical dialogue and information transfer to the cortex (Buzsáki 1996; Sirota et al. 2003; Steriade 2006; Clemens et al. 2011; Mölle and Born 2011; Staresina et al. 2015). Indeed, our previously published work from the present study provided supporting evidence that the density of thalamocortical sleep spindles (11–16 Hz) during overnight sleep is related to enhanced hippocampal–cortical functional connectivity measures, and increased similarity, or greater representational overlap, among memories in the ventromedial prefrontal cortex (vmPFC) (Cowan et al. 2020). Yet, while some prior work has shown that features of sleep, including spindle density and the duration of non-REM SWS, are related to decreased retrieval-related hippocampal activation for memoranda learned prior to sleep (Takashima et al. 2006; Baran et al. 2016; Hennies et al. 2016), it remains unclear how the reactivation of hippocampal traces during replay may impact the way memories are organized along the long axis of the hippocampus.To examine the effects of sleep-dependent consolidation on the neural representation of memories in the hippocampus, we designed a within-participant 3-d study using overnight polysomnography (PSG), functional magnetic resonance imaging (fMRI), and behavioral measures of memory (Fig. 1). In this study, aspects of which have been previously published (Cowan et al. 2020), participants first studied a list of word–image pairs before sleeping overnight (Sleep List), during which PSG was recorded. Upon waking in the morning, participants studied a new list of pairs (Morning List). The word–image pairs from these two lists were then restudied while undergoing an fMRI scan, intermixed with a third, novel list of pairs (Single Study List). Associative memory was tested immediately after the scan and again 24 h later. We compared measures of multivariate pattern similarity and univariate BOLD signal for the lists learned prior to, or after, sleep to probe how modulating the opportunity for sleep-dependent consolidation impacts the way memories are organized across the long axis of the hippocampus. Furthermore, our design allowed us to examine how features of overnight sleep are related to the representational organization of memories learned prior to the sleep period, as well as the behavioral benefit of changes to the organization of these memories. Thus, our study provides a novel examination of the effects of sleep-dependent consolidation on the representation of memories along the long axis of the hippocampus.Open in a separate windowFigure 1.Study design. For all encoding and restudy sessions, participants were asked to form an association between a word and an image. Participants first encoded the Sleep List (blue) before sleeping overnight while polysomnography was recorded. The next morning (day 2), participants encoded a second set of novel word–image pairs (Morning List). After a short delay (∼2 h), participants restudied these two sets of pairs, intermixed with novel pairs (Single Study List) in the functional magnetic resonance imaging (fMRI) scanner. Source memory was tested immediately after the scan and after a 24-h delay (day 3). 相似文献
39.
From an anecdotal rumination, the authors make the case for consideration of past reflections, in what they call 'composting', to inspire and enrich new, different and currently ongoing reflective activity and initiatives. 相似文献
40.
This study examines two overlapping longitudinal samples of U.S. couples with children, covering a period of 15 years after the first child's birth. The first sample extended from the pregnancy with a first child until that child was 5.5 years old; the second from ages 4.5 to 14.5. Growth curve analyses revealed that marital satisfaction declined over 15 years for both husbands and wives. Attachment security measured in the second sample was associated with greater marital satisfaction, but did not buffer against declines in marital satisfaction over time. Husbands' lower initial level of marital satisfaction measured around the first child's transition to school was the only significant predictor of marital dissolution. The discussion emphasizes theoretical and practical implications of these findings. 相似文献