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Amnesia or retrieval deficit? Implications of a molecular approach to the question of reconsolidation 下载免费PDF全文
Post-retrieval interference with a memory has uncovered a phenomenon known to the field as reconsolidation. In this article, we will review the specific molecular mechanisms that have been implicated in reconsolidation. As a result of numerous studies over the past five years, it can now be said with a fair amount of certainty that reconsolidation is not a recapitulation of the mechanisms underlying consolidation, despite what the term "reconsolidation" may suggest. Therefore, in addition to reviewing the known mechanisms of reconsolidation, we will propose that two experimental approaches involving the targeting of specific molecular mechanisms, and the study of these mechanisms during retrieval, may serve useful to the field as it is now able to advance beyond comparisons between consolidation and reconsolidation. 相似文献
123.
Psychometric characteristics of the Slosson Auditory Perception Skills Screener were studied using three independent samples of boys and girls ages 5-10 years (N= 1,170). Internal consistency of scores ranged from .83 to .90 for the total scale, while 30-day test-retest reliability was .82 (n=58). A convergent validity coefficient between the Slosson Auditory Perception Skills Screener and Test of Auditory Perceptual Skills-Revised Total Score was .59 (n=67, p<.05). Thus, scores derived from administration of the Slosson Auditory Perception Skills Screener had adequate internal consistency and temporal stability, as well as good convergent validity. 相似文献
124.
This study assessed the relationship between borderline personality disorder (BPD) features and treatment utilization over a 2-year time period. Participants included 349 18-year-old nonclinical young adults, approximately one-half of whom endorsed significant borderline features. The laboratory phase of the study involved the administration of self-report and interview-based assessments of BPD psychopathology at Wave 1, as well as interviews targeting Axis I psychopathology and treatment utilization history at Wave 2 (2 years later). Results indicated that borderline features prospectively predicted utilization of psychopharmacological treatment above and beyond what was accounted for by gender, lifetime Axis I psychopathology, and nonBPD Axis II psychopathology. The borderline feature most strongly associated with treatment utilization was affective instability. 相似文献
125.
Trent A. Petrie Laura J. Austin Barbara J. Crowley Annette Helmcamp Courtney E. Johnson Regan Lester Rebecca Rogers Jeff Turner Kevin Walbrick 《Sex roles》1996,35(9-10):581-602
Sociocultural expectations of attractiveness for women have been studied extensively, but little research has focused on this topic with males. Using the two most popular men's fashion magazines (GQand Esquire), this study examined article and advertisement content as well as male models' body sizes to determine the extent to which men have received messages from the media on how to behave (e.g., diet, exercise) and look over a 32 year period (i.e., 1960–1992). Linear trend analyses revealed that the number of messages concerning physical fitness and health have increased as has the general popularity of health and fitness activities. Messages concerning weight and beauty, however, have declined since the late 1970s. In spite of these changes, measures of male models' body sizes have not changed significantly since the 1960s. These findings are discussed in the context of the sociocultural approach to eating disorders and recommendations for future research are provided. 相似文献
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O'Neil KA Puleo CM Benjamin CL Podell JL Kendall PC 《Suicide & life-threatening behavior》2012,42(3):305-317
Evidence is mixed regarding an independent association between anxiety and suicidality in youth. Study 1 examined suicidal ideation in treatment-referred, anxiety-disordered youth (N = 312, aged 7-17). Forty-one percent of anxiety-disordered youth endorsed suicidal ideation. Anxiety disorder severity, global impairment, and current depressive symptoms predicted suicidal ideation in a multivariate model. Study 2 compared youth (N = 216, aged 7-14) with and without anxiety disorders. Higher rates of suicidal ideation were associated with anxiety diagnosis, and levels of anxiety predicted suicidal ideation after controlling for comorbid depressive disorders, current depressive symptoms, and global impairment. Results support an association between anxiety disorders and suicidal ideation in treatment-referred youth and recommend routine screening for suicidal ideation in this population. 相似文献
128.
Matti T. Keinänen Jeffrey G. Johnson Elizabeth S. Richards Elizabeth A. Courtney 《Psychoanalytic Psychotherapy》2013,27(1):65-91
Borderline personality disorder (BPD) is a serious personality disorder characterized by affective instability, impulsivity and interpersonal disturbance. Currently, intensive research is being conducted concerning the aetiology of BPD, including research on neurobiological, temperamental, psychosocial and cultural risk factors. This study focuses on psychosocial risk factors while other risk factors are taken into account in the discussion of the development of BPD. To our knowledge, no systematic review of the evidence-based medicine literature concerning this theme has been made thus far. However, understanding psychosocial risk factors of BPD is important in order to develop psychotherapeutic treatment models and methods. We provide a systematic review of the literature focusing on psychosocial risk factors for BPD. Utilizing this knowledge, we discuss how these data may be used when studying the development of borderline personality disorder and the treatment of borderline personality disorder. 相似文献
129.
Comprehension is integral to enjoyment of media narratives, yet our understanding of how viewers create the situation models that underlie comprehension is limited. This study utilizes two models of comprehension that had previously been tested with factual texts/videos to predict viewers' recall of entertainment media. Across five television/film clips, the landscape model explained at least 29% of the variance in recall. A dual coding version that assumed separate verbal and visual representations of the story significantly improved the model fit in four of the clips, accounting for an additional 15–29% of the variance. The dimensions of the event‐indexing model (time, space, protagonist, causality, and intentionality) significantly moderated the relationship between the dual coding model and participant recall in all clips. 相似文献
130.