Matching of movements made independently by the two arms in normal humans

Comparisons were made of voluntary movements of the right and left arms in normal human subjects. A series of movements of different amplitudes, made at the subject' own speed, was performed with one limb. After a rest period, the same series was repeated with the contralateral limb. The relation between movement peak velocity and movement amplitude was linear and was the same for both arms. With repeated testing over periods up to two months, the slope of the peak velocity-amplitude relation decreased during the first week, thereafter remaining unchanged. In a second series of experiments, six normal subjects continuously wore a 1 lb (0.45 kg) weight strapped to their left (non-dominant) forearm for up to 1 week. This resulted in an increase in the slope of the peak-velocity/amplitude relation in this arm. A parallel change occurred in movements made independently by the right (non-loaded) arm. A similar matching of movement performance of the two limbs was seen following removal of the weight. The data is interpreted as proving support for the hypothesis that there is a single movement "command" which is applied to both limbs. The interaction of this command with the limbs which have similar second-order mechanical properties yields similar movements even when they are made independently.     

Delayed symbolic matching in honeybees (Apis mellifera)

In a recent experiment on short-term memory (P. A. Couvillon, T. P. Ferreira, & M. E. Bitterman, 2003), honeybees (Apis mellifera) learned to choose between 2 colors on the basis of immediately preceding experience with 1 of them. Some learned to choose the same color as the sample (perseveration or matching), others to choose the alternative color (alternation or nonmatching). Performance in the 2 problems was very much the same. In the present experiment, honeybees learned no less readily to choose between the 2 colors on the basis of sample stimuli that were different from the colors (symbolic matching). A simple associative interpretation of the results is proposed.     

Interactive Team Cognition

Cognition in work teams has been predominantly understood and explained in terms of shared cognition with a focus on the similarity of static knowledge structures across individual team members. Inspired by the current zeitgeist in cognitive science, as well as by empirical data and pragmatic concerns, we offer an alternative theory of team cognition. Interactive Team Cognition (ITC) theory posits that (1) team cognition is an activity, not a property or a product; (2) team cognition should be measured and studied at the team level; and (3) team cognition is inextricably tied to context. There are implications of ITC for theory building, modeling, measurement, and applications that make teams more effective performers.     

A Linked Muscular Activation Model for Movement Generation and Control

A new model for movement control is presented which incorporates characteristics of impulse-variability and mass-spring models. Movements in the model were controlled with phasic torque impulses in agonist and antagonist muscles and a tonic agonist torque.

Characteristics of the phasic agonist and antagonist torque profiles were based on observed properties of movement-related EMGs and muscle isometric torques. Variability of the phasic impulses depended on impulse magnitude as in impulse-variability models. The model therefore predicted a speed-accuracy tradeoff for limb movement. The time of onset and magnitude of the antagonist torque depended on the magnitude of the preceding agonist torque as indicated in studies of movement-related EMGs. This led to the new concept of linkage between the agonist and antagonist muscle forces which was shown to be important for reducing variability of fast movements. Progressive development of linkage during practice could explain the previous findings of decreased movement variability with practice coupled with increased variability of movement-related EMGs.

It was concluded that an inherently variable motor system deals with the variability associated with generation of large muscle forces by linking the forces produced by opposing muscles. In this way, variability in net joint torques and in movements can be decreased without the need for the nervous system to closely regulate the individual torques.     

Neural basis for sentence comprehension deficits in frontotemporal dementia

Many patients with frontotemporal dementia (FTD) have impaired sentence comprehension. However, the pattern of comprehension difficulty appears to vary depending on the clinical subgroup. The purpose of this study was to elucidate the neural basis for these deficits in FTD. We studied patients with two different presentations: Three patients with Progressive Non-Fluent Ahasia (PNFA), and five non-aphasic patients with a dysexecutive and social impairment (EXEC). The FTD patient subgroups were compared to a cohort of 11 healthy seniors with intact sentence comprehension. We monitored regional cerebral activity with blood oxygen level dependent (BOLD) functional magnetic resonance imaging (fMRI) while subjects read sentences featuring both a grammatically complex object-relative center-embedded clause and a long linkage between the head noun phrase (NP) and the gap where the NP is interpreted in the center-embedded clause. Subjects decided whether the agent of the action is a male or a female. Healthy seniors activated both ventral portions of inferior frontal cortex (vIFC) and dorsal portions of IFC (dIFC) in the left hemisphere, often associated with grammatical and working memory components of these sentences, respectively. PNFA patients differed from healthy controls since they have reduced activation of left vIFC, while EXEC patients have less recruitment of left dIFC. We conclude that FTD subgroups have distinct patterns of sentence comprehension difficulty in part because of selective interruptions of a large-scale neural network for sentence processing.     

Movement related EMGs become more variable during learning of fast accurate movements

Human subjects performed simple flexion and extension movements about the elbow in a visual step-tracking paradigm. Movements were self-terminated. Subjects were instructed to increase movement velocity while maintaining end-point accuracy during practice. The effects of practice on the pattern and variability of EMG activity of the biceps and triceps muscles were studied. Initial movements were performed using reciprocal phasic activation of agonist and antagonist muscles as indicated by surface EMGs. With practice, increases in movement speed were associated with larger agonist and antagonist bursts and an earlier onset of the antagonist burst. Decreased duration of the premovement antagonist silence was also observed during practice. Decreases in variability of movements during practice were not accompanied by equivalent decreases in variability of the associated EMGs. Surprisingly, both agonist and antagonist EMGs were more variable in faster, practiced movements. The combined agonist-antagonist EMG variability depended on both movement speed and trajectory variability. Lower variability in movements in the presence of greater variability in the related EMGs occurred because of linked variations in agonist and antagonist muscle activities. Variations in the first agonist burst were often compensated for by associated variations in the antagonist and late agonist bursts. These linked variations maintained the limb trajectory relatively constant in spite of large variations in the first agonist burst. Modifications to impulse-variability models are therefore needed to explain compensations for variability in accelerative impulses (produced by the first agonist burst) by linked variations in impulses for deceleration (produced by the antagonist and late agonist bursts).     

Neural correlates of successful and unsuccessful verbal memory encoding

Recent neuroimaging studies suggest that episodic memory encoding involves a network of neocortical structures which may act interdependently with medial temporal lobe (mTL) structures to promote the formation of durable memories, and that activation in certain structures is modulated according to task performance. Functional magnetic resonance imaging (fMRI) was used to determine the neural structures recruited during a verbal episodic encoding task and to examine the relationship between activation during encoding and subsequent recognition memory performance across subjects. Our results show performance-correlated activation during encoding both in neocortical and medial temporal structures. Neocortical activations associated with later successful and unsuccessful recognition memory were found to differ not only in magnitude, but also in hemispheric laterality. These performance-related hemispheric effects, which have not been previously reported, may correspond to between-subject differences in encoding strategy.