Stress, Glucocorticoids, and Damage to the Nervous System: The Current State of Confusion

An extensive literature demonstrates that glucocorticoids (GCs), the adrenal steroids secreted during stress, can have a broad range of deleterious effects in the brain. The actions occur predominately, but not exclusively, in the hippocampus, a structure rich in corticosteroid receptors and particularly sensitive to GCs. The first half of this review considers three types of GC effects: a) GC-induced atrophy, in which a few weeks' exposure to high GC concentrations or to stress causes reversible atrophy of dendritic processes in the hippocampus; b) GC neurotoxicity where, over the course of months, GC exposure kills hippocampal neurons; c) GC neuroendangerment, in which elevated GC concentrations at the time of a neurological insult such as a stroke or seizure impairs the ability of neurons to survive the insult. The second half considers the rather confusing literature as to the possible mechanisms underlying these deleterious GC actions. Five broad themes are discerned: a) that GCs induce a metabolic vulnerability in neurons due to inhibition of glucose uptake; b) that GCs exacerbate various steps in a damaging cascade of glutamate excess, calcium mobilization and oxygen radical generation. In a review a number of years ago, I concluded that these two components accounted for the deleterious GC effects. Specifically, the energetic vulnerability induced by GCs left neurons metabolically compromised, and less able to carry out the costly task of containing glutamate, calcium and oxygen radicals. More recent work has shown this conclusion to be simplistic, and GC actions are shown to probably involve at least three additional components: c) that GCs impair a variety of neuronal defenses against neurologic insults; d) that GCs disrupt the mobilization of neurotrophins; e) that GCs have a variety of electrophysiological effects which can damage neurons. The relevance of each of those mechanisms to GC-induced atrophy, neurotoxicity and neuroendangerment is considered, as are the likely interactions among them.     

Better Late than Never? The Relationship between Ratings of Attendance,Punctuality, and Overall Job Performance among Nursing Home Employees

This study examined the relationship between lateness, absenteeism, and overall job performance among nursing home employees. We addressed four issues: (a) agreement between subordinate and superior in their ratings, (b) the stability of rated lateness and rated absenteeism over 6 months, (c) the correlation between ratings of lateness and absenteeism assigned by the worker to himself or herself and the corresponding ratings from supervisors, and (d) the relationship of rated lateness and rated absenteeism to impressions of overall job performance. Neither attendance nor punctuality showed inter‐rater agreement between the worker and his/her supervisor on either of the two occasions. Ratings of attendance were not stable across time for either the subordinate (r=.16) or the supervisor (r=.04), but punctuality ratings showed moderate temporal stability over 6 months for both subordinate (r=.59) and supervisor (r=. 41) impressions. On the first administration of the rating form, attendance and punctuality were not significantly correlated to each other in either the workers' self‐ratings (r=.17) nor the supervisors' ratings of the workers (r=.08). On the second administration, however, these two facets were moderately correlated with each other in both workers' (r=.54) and supervisors' (r=. 39) impressions of employee behavior. Compared with attendance, punctuality was somewhat more highly correlated with impressions of overall job performance from the perspective of the worker herself/himself as well as the supervisor.     

Coaching behaviors associated with changes in fear of failure: changes in self-talk and need satisfaction as potential mechanisms

Cognitive-interpersonal and motivational mechanisms may regulate relations between youth perceptions of interpersonal aspects of the social ecology and their fear-of-failure (FF) levels. Youth (N=165) registered for a summer swim league rated their fear of failure at the beginning, middle, and end of the season. Extensive model comparisons indicated that youths' end-of-season ratings of coach behaviors could be reduced to three factors (affiliation, control, blame). Perceived control and blame from coaches predicted residualized change in corresponding aspects of youths' self-talk, but only changes in self-blame positively predicted changes in FF levels during the season. Perceived affiliation from coaches predicted autonomy need satisfaction which, in turn, negatively predicted the rate of change in FF levels during the season. These findings indicate that (a) youth perceptions of coaches were directly and indirectly related to acute socialization of FF and (b) both cognitive-interpersonal and motivational mechanisms contributed to this socialization process. Further research is needed to test for developmental differences in these mechanisms to determine whether findings generalize to more heterogeneous and at-risk populations and to investigate other potential social-ecological influences on socialization.     

Using Structural Analysis in Natural Settings: A Responsive Functional Assessment Strategy

Since the reauthorization of IDEA (1997), the use of functional assessments to examine factors that are related to students challenging behaviors has gained increasing attention in the literature. Over the past five years, several groups of investigators have conducted systematic analyses of the current status of the use of functional assessment in relation to students with or at risk for emotional/behavioral disorders (EBD). Their findings outline a number of critical, applied research issues for the field to consider. The purpose of this paper is to respond to a number of these issues by highlighting the relevance of structural analysis in addition to and in some cases in lieu of more traditional functional assessments. A brief review of current trends in the functional assessment research is presented as well as a rational for the use of structural analysis to examine the occurrence of appropriate behavior for students with EBD. Finally, illustrations of studies conducting structural analyses in classrooms settings are provided.     

Being a non-drinking student: An interpretative phenomenological analysis

Recent research suggests that safer student alcohol consumption might be assisted by understanding how social occasions are managed by non-drinkers. In-depth, semi-structured interviews with five 19 – 22 year old non-drinking English undergraduates were subjected to interpretative phenomenological analysis. We present five inter-linked themes: ‘living with challenges to non-drinking’; ‘seeing what goes on in drinking environments’; ‘dealing with conversations about non-drinking (making excuses vs. coming out)’; ‘knowing which friends care about you’; and ‘the importance of minimising “legroom” for peer pressure’. Participants felt under persistent peer scrutiny (as a form of peer pressure) and could feel alienated in drinking environments. Talking about non-drinking was characterised by whether to ‘come out’ (as a non-drinker) or ‘fake it’ (e.g. ‘I’m on antibiotics’). Loyal friendships were reported as particularly important in this context. The decision not to drink was experienced as providing a successful buffer to peer pressure for former drinkers. Our findings unsettle traditional health promotion campaigns which advocate moderate drinking among students without always suggesting how it might be most successfully accomplished and offer tentative guidance on how non-drinking during specific social occasions might be managed more successfully. Findings are discussed in relation to extant literature and future research directions are suggested.     

Evaluative Criteria and Consequences Associated with Failure and Success for Elite Athletes and Performing Artists

Fears of failure and success are widely regarded as salient threats to performance in a variety of domains yet scientific understanding of these constructs is still in its infancy. Sixteen elite athletes and performing artists participated in in-depth interviews to shed light on the nature of the cognitive-motivational-relational appraisals associated with these fears. Results revealed distinct criteria for evaluations of failure and success, as well as the perceived consequences of failure and success. It was concluded that the criteria used to evaluate failure and success are sufficiently distinct to suggest that perceptions of failure and success should not be thought of as a bipolar phenomenon. The consequences of failure and success were used to form multidimensional models of fear of failure and fear of success.     

Family Loss and Hospital Suicide

In 19 consecutive cases of inpatient suicide occurring over many years, 18 out of the 19 cases (95 percent) were judged to have a significant “family” loss issue affecting the suicide. In five cases (26 percent), there seemed to be a powerful institutional attachment and loss threatened that attachment. In 13 cases (68 percent), a major family issue was involved which included events that estranged the patient from the family (real or imagined); divorce or separation issues; death or illness of a significant other; a family that insisted on continued treatment (and/or growth). In 13 cases (68 percent), significant communication from or about the “family” occurred which seemed to have an impact on the suicidal behavior often within days of the final event. In 10 cases (53 percent), an actual family visit had occurred within two weeks of the death. These issues are discussed and case examples presented.     

Age and pre quit-day attrition during smoking cessation treatment

ABSTRACT

The present study aimed to replicate the finding that younger age predicts higher pre quit-day attrition. Our second aim was to explain this relation by examining empirically and theoretically informed age-related risk factors for low smoking cessation treatment engagement. 136 participants (M _age = 44.2 years, SD = 11.3 years; age = 22–64 years) were randomized to 15-weeks of either 1) an exercise intervention (n = 72) or 2) a wellness education control condition (n = 64). First, a logistic regression analysis was employed to test whether younger adults were more likely than older adults to drop prior to quit date. Next, we assessed whether smoking related health concerns, social expectancies, and/or perceived severity of craving affected the strength of the relation between age and attrition, by adding these three variables to the logistic regression along with age. The logistic regression model indicated that younger age and treatment condition were significantly related to the odds of dropping from treatment prior to the scheduled quit date. Further, health concerns, social expectancies, and/or perceived severity of cravings did not account for the effect of age on pre quit-day attrition. These findings highlight the importance of identifying empirically and theoretically informed variables associated with the pre quit-day attrition problem of young smokers.