The convergent and concurrent validity of trait-based prototype assessment of personality disorder categories in homeless persons

The DSM-5 proposal indicates that personality disorders (PDs) be defined as collections of maladaptive traits but does not provide a specific diagnostic method. However, researchers have previously suggested that PD constructs can be assessed by comparing individuals' trait profiles with those prototypic of PDs and evidence from the five-factor model (FFM) suggests that these prototype matching scores converge moderately with traditional PD instruments. The current study investigates the convergence of FFM PD prototypes with interview-assigned PD diagnoses in a sample of 99 homeless individuals. This sample had very high rates of PDs, which extends previous research on samples with more modest prevalence rates. Results indicated that diagnostic agreement between these methods was generally low but consistent with the agreement previously observed between explicit PD measures. Furthermore, trait-based and diagnostic interview scores evinced similar relationships with clinically important indicators such as abuse history and past suicide attempts. These findings demonstrate the validity of prototype methods and suggest their consideration for assessing trait-defined PD types within DSM-5.     

Assessment of children's receptive vocabulary using event-related brain potentials: Development of a clinically valid test

The combined verbal and motor impairments characteristic of children with disorders such as Cerebral Palsy (CP) frequently compromise the accuracy of standard psychometric assessments. What is needed is a test to measure language that does not require verbal or motor responses. This study was designed to determine whether single-word receptive vocabulary could be assessed in young children without CP, using an ERP-compatible test based on Form M of the Peabody Picture Vocabulary Test-Revised (PPVT-R). Fifteen 10-year-old children with normal levels of psychometric intelligence participated. Ninety pictures were selected from the PPVT-R (Form M), representing three levels of single-word receptive vocabulary (Preschool, Child-Adolescent, Adult). Each picture was presented twice (pseudo-random), once paired with a spoken word that was semantically congruent with the picture and once paired with a semantically incongruent word. The children's N400 was significantly larger to incongruent than to congruent pairs, but only when the vocabulary was within their repertoire. The results are discussed in terms of electrophysiologic correlates of acquired language and the clinical use of this ERP test as an adjunct to assessing patients with moderate to severe communication and/or motor impairments (e.g., cerebral palsy, autism, head injury).     

患者知情同意权实现的伦理思考与法律保护

随着医学科学的发展,患者的知情同意已是医学实践的一个基本伦理观念和原则,但是,它的实现不仅需要道德规范的约束,而且还需要法律的保护.     

Locke's Theory of Demonstration and Demonstrative Morality

Locke famously claimed that morality was capable of demonstration. But he also refused to provide a system of demonstrative morality. This paper addresses the mismatch between Locke's stated views and his actual philosophical practice. While Locke's claims about demonstrative morality have received a lot of attention it is rare to see them discussed in the context of his general theory of demonstration and his specific discussions of particular demonstrations. This paper explores Locke's general remarks about demonstration as well as his claims about demonstration in natural philosophy, mathematics, and morality. Careful attention to these detailed discussions motivates a reevaluation of Locke's views on demonstrative knowledge of morality. Specifically, while Locke did believe that some demonstrative moral knowledge might be in‐principle available to us he also believed that facts about the difficulty of demonstration meant that this knowledge would in‐practice be largely unattainable.     

Does eye gaze indicate implicit knowledge of false belief? Charting transitions in knowledge

Three-year-olds sometimes look to the correct location but give an incorrect verbal answer in a false belief task. We examined whether correct eye gaze among 3- to 5-year-old children indexed unconscious knowledge or low confidence conscious knowledge. Children "bet" counters on where they thought a story character would go. If children were conscious of the knowledge conveyed by their eye gaze then they should have bet modestly on their explicit answer (i.e., been unsure whether this answer or the answer conveyed through eye direction was correct). We found that children bet very highly on the location consistent with their explicit answer, suggesting that they were not aware of the knowledge conveyed through their eye gaze. This result was supported by a number of conditions that showed that betting was a sensitive measure of even small degrees of uncertainty. The results shed light on false-belief understanding, the implicit-explicit distinction, and transitional knowledge. We argue that the transition to a full understanding of false belief is marked by periods of implicit knowledge and explicit understanding with low confidence.     

Regret in Decision Making

Decision research has only recently started to take seriously the role of emotions in choices and decisions. Regret is the emotion that has received the most attention. In this article, we sample a number of the initial regret studies from psychology and economics, and trace some of the complexities and contradictions to which they led. We then sketch a new theory, decision justification theory (DJT), which synthesizes several apparently conflicting findings. DJT postulates two core components of decision–related regret, one associated with the (comparative) evaluation of the outcome, the other with the feeling of self–blame for having made a poor choice. We reinterpret several existing studies in DJT terms. We then report some new studies that directly tested (and support) DJT, and propose a number of research issues that follow from this new approach to regret.     

Out of the body: embodiment and its vicissitudes

Body‐mind dualism and the consequent neglect of the body of the analyst can have important negative effects on the analytical process leading all too often to misinterpretations of the analysand's verbal and non‐verbal communications and to disturbances of analytical temporality. This is intensified when we are dealing with individuals where disembodiment and states of psychic deadness are central features. The paper explores the philosophical roots of the idea of a disembodied mind and the way in which this impacts our relationship with the world. While André Green's concept of the dead mother and disturbances in the sense of self‐agency have been held to play an important role in states of psychic deadness, I suggest that it is rather disturbances in the sense of body ownership and of the body image which are more central. The paper then discusses the particular kinds of countertransference that can be evoked in the analyst when we find ourselves dealing with this type of patient and suggests how we can use our embodied countertransference to become aware of and elaborate our own feelings of deadness in order to overcome the loss of temporality that is characteristic of such states. This is illustrated with reference to my work with a young man with a masochistic perversion and a severe disturbance of the body image with an accompanying profound sense of psychic deadness.     

Cognitive aesthetics of alchemical imagery

Jung's contribution to the understanding of the relevance of psychology to alchemy has become increasingly invalidated by the ahistorical nature of his approach, just as his tendency to ignore the importance of cognitive aesthetics for an improved comprehension of the functions of alchemical images has prevented Jungians from further extending Jung's insight of the importance of alchemy for psychology. This paper explores the history of the development of alchemical illustrations in Western Europe from the 14^th to the 16^th century, tracing the emergent processes over time. It is only when we take into consideration the historical dimension and the aesthetics of alchemical imagery that it becomes possible to demonstrate how the increasing use of certain aesthetic techniques such as the disjunction and recombination of separate metaphorical elements of previous illustrations, the use of compressive combinations and the use of framing devices worked to gradually increase the cognitive function and the symbolical power of the images. If alchemy is still relevant to psychotherapy it is exactly because it helps us to understand the importance of cognitive aesthetics in our approach to the images, metaphors and narratives of our patients.     

An fMRI investigation of a novel analogue to the Trail-Making Test

The Trail-Making Test (TMT) is a widely used neuropsychological measure that assesses visuomotor abilities and cognitive flexibility. For the TMT-A condition participants are required to locate and connect numbers (i.e. 1-2-3…) while in the TMT-B condition participants perform the set-shifting task of locating and connecting numbers and letters (i.e. 1-A-2-B…). The TMT-B condition has shown impairments in many clinical populations, particularly schizophrenia patients, but the neurobiological underpinning of the task can be difficult to discern given pragmatic obstacles in adapting the task for neuroimaging. In a behavioural testing experiment we demonstrated a close correspondence between performance on the standard TMT and a novel, computer programmed adaptation of the TMT (pcTMT). The pcTMT was designed for functional magnetic resonance imaging (fMRI) administration and neuroimaging data for this task were obtained in. A whole brain analysis revealed significantly greater activation during the pcTMT-B relative to the pcTMT-A in right inferior/middle frontal cortices, right precentral gyrus, left angular gyrus/left middle temporal gyrus. These results identify the regions that most likely underlie cognitive flexibility during the TMT and are candidate regions underlying the impairment of groups with poor set-shifting abilities.     

ON THE PRAGMATICS OF SOCIAL THEORY: THE CASE OF ELIAS'S “ON THE PROCESS OF CIVILIZATION”

This paper proposes a new approach to the study of sociological classics. This approach is pragmatic in character. It draws upon the social pragmatism of G. H. Mead and the sociology of texts of D. F. McKenzie. Our object of study is Norbert Elias's On the Process of Civilization. The pragmatic genealogy of this book reveals the importance of taking materiality seriously. By documenting the successive entanglements between human agency and nonhuman factors, we discuss the origins of the book in the 1930s, how it was forgotten for 30 years, and how in the mid‐1970s it became a sociological classic. We explain canonization as a matter of fusion between book's material form and its content, in the context of the paperback revolution of the 1960s, the events of May 1968, and the demise of Parsons’ structural functionalism, and how this provided Elias with an opportunity to advance his model of sociology.