Effects of anesthetic agents on socially transmitted olfactory memories in mice

Mice can learn a food preference from odor cues transmitted on the breath of a conspecific, even if the “demonstrator” is anesthetized. To our knowledge there are no studies examining the effect of anesthetizing the “observer” on development of memory for socially transmitted food preferences (STFP). In Experiment 1 we found that 2–4 month-old F2 C57Bl/6x129sv male and female mice demonstrated a STFP after a 5 min exposure to an anesthetized demonstrator mouse when tested 24 h later. In Experiment 2, observer mice anesthetized with Sagatal (60 mg/kg) prior to the “social interaction” preferentially avoided the cued food when tested 24 h later. This aversion was not due to any overt aversive effects of this dose of Sagatal because mice that ate the food and were then anesthetized, or could only smell the food for 5 min while anesthetized, showed no preference or aversion. In a third experiment we found that the Sagatal-induced aversion was not a general property of anesthesia because there were varied results produced by observer mice treated with anesthetic drugs with different mechanisms of action. Vetalar (200 mg/kg) and Rompun (10 mg/kg) treated animals ate similar amounts of cued and non-cued food at test, indicating an absence of learning. Hypnorm (0.5 ml/kg) treated animals showed a preference for the cued food whereas those treated with Hypnovel (2.5 ml/kg) showed an aversion to the cued food. These results show that the food aversion observed with Sagatal is not a general property of anesthetic agents, but appears to be restricted to those acting primarily on the GABAergic system. Thus, we have shown that under certain conditions it is possible for an anesthetized observer mouse to learn a preference or aversion of a socially-linked olfactory cue.     

Personality Neuroscience and the Biology of Traits

Personality neuroscience involves the use of neuroscience methods to study individual differences in behavior, motivation, emotion, and cognition. Personality psychology has contributed much to identifying the important dimensions of personality, but relatively little to understanding the biological sources of those dimensions. However, the rapidly expanding field of personality neuroscience is increasingly shedding light on this topic. This article provides a survey of progress in the use of neuroscience to study personality traits, organized using a hierarchical model of traits based on the Big Five dimensions: Extraversion, Neuroticism, Agreeableness, Conscientiousness, and Openness/Intellect. Evidence is reviewed for hypotheses about the biological systems involved in each trait.     

From Theory to Intervention: Mapping Theoretically Derived Behavioural Determinants to Behaviour Change Techniques

Theory provides a helpful basis for designing interventions to change behaviour but offers little guidance on how to do this. This paper aims to illustrate methods for developing an extensive list of behaviour change techniques (with definitions) and for linking techniques to theoretical constructs. A list of techniques and definitions was generated from techniques published in two systematic reviews, supplemented by "brainstorming" and a systematic search of nine textbooks used in training applied psychologists. Inter-rater reliability of extracting the techniques and definitions from the textbooks was assessed. Four experts judged which techniques would be effective in changing 11 theoretical constructs associated with behaviour change. Thirty-five techniques identified in the reviews were extended to 53 by brainstorming and to 137 by consulting textbooks. Agreement for the 53 definitions was 74.7 per cent (15.4% cells completed and 59.3% cells empty for both raters). Agreement about the link between the 35 techniques and theoretical constructs was 71.7 per cent of 385 judgments (12.2% agreement that effective and 59.5% agreement that not effective). This preliminary work demonstrates the possibility of developing a comprehensive, reliable taxonomy of techniques linked to theory. Further refinement is needed to eliminate redundancies, resolve uncertainties, and complete technique definitions.     

Neurophysiology and neuroanatomy of reflexive and voluntary saccades in non-human primates

A multitude of cognitive functions can easily be tested by a number of relatively simple saccadic eye movement tasks. This approach has been employed extensively with patient populations to investigate the functional deficits associated with psychiatric disorders. Neurophysiological studies in non-human primates performing the same tasks have begun to provide us with insights into the neural mechanisms underlying many cognitive functions. Here, we review studies that have investigated single neuron activity in the superior colliculus (see glossary), frontal eye field, supplementary eye field, dorsolateral prefrontal cortex, anterior cingulate (see glossary) cortex and lateral intraparietal area associated with the performance of visually guided saccades, anti-saccades and memory-guided saccades in awake behaving monkeys.     

The Six-Sided Vision of Said Nursi: Towards a Spiritual Architecture of the Risale-i Nur

Bediüzzaman Said Nursi, the eponymous progenitor of the contemporary Nurculuk movement, was arguably the most influential, if woefully under-researched, Turkish Muslim thinker of the twentieth century. Nurculuk, a faith-based movement consisting of an estimated seven million followers worldwide, stands out from other contemporary Muslim religious and ideological groupings not only for its uncompromising focus on the renewal of individual rather than collective faith, but also for its eschewal of any kind of religiously legitimized violence or militancy for the sake of politico-ideological ends. This article is an attempt at an overview of Nursi's idiosyncratically irenic approach to the highly contentious issue of jihad, itself key to our understanding of the staunch apoliticism he espoused in later life.     

Threat in dreams: an adaptation?

Revonsuo's influential Threat Simulation Theory (TST) predicts that people exposed to survival threats will have more threat dreams, and evince enhanced responses to dream threats, compared to those living in relatively safe conditions. Participants in a high crime area (South Africa: n=208) differed significantly from participants in a low crime area (Wales, UK: n=116) in having greater recent exposure to a life-threatening event (chi([1,N=186])(2)=14.84, p<.00012). Contrary to TST's predictions, the SA participants reported significantly fewer threat dreams (chi([1,N=287])(2)=6.11, p<.0134), and did not differ from the Welsh participants in responses to dream threats (Fisher's Exact test, p=.2478). Overall, the incidence of threat in dreams was extremely low-less than 20% of dreams featured realistic survival threats. Escape from dream threats occurred in less than 2% of dreams. We conclude that this evidence contradicts key aspects of TST.     

Shooting the messenger won’t change the news

Malcolm-Smith, Solms, Turnbull and Tredoux [Malcolm-Smith, S., Solms, M., Turnbull, O., & Tredoux, C. (2008). Threat in dreams: An adaptation? Consciousness and Cognition, 17, 1281–1291.] conducted a rigorous study that sampled two populations differentially exposed to threat in real life, and found that critical predictions from the Threat Simulation Theory of dreams [Revonsuo, A. (2000a). The reinterpretation of dreams: An evolutionary hypothesis of the function of dreaming. Behavioral and Brain Sciences, 23, 877-901.; Revonsuo, A. (2000b). Did ancestral humans dream for their lives? Behavioral and Brain Sciences, 23, 1063–1082.] were not supported. Specifically, we found no evidence of increased realistic threats to physical survival or enhanced threat avoidance in the dreams of those from the exposed population. Revonsuo and Valli’s [Revonsuo, A., & Valli, K. (2008). How to test the threat simulation theory. Consciousness and Cognition, 17, 1292-1296.] commentary on our study argues that the methods we used are so flawed as to render the results meaningless. In this response article, we address the criticisms raised in their commentary.     

Evaluating the Evaluators: Perceptions of Interviewers by Rejected Job Applicants as a Function of Interviewer and Applicant Sex1

Students who had recently had an unsuccessful job interview rated the competence of their interviewer and completed the Women As Managers Scale (WAMS; Terborg, Peters, Ilgen, & Smith, 1977 ). The results showed an impact of the sex of interviewer on judgments of interviewer competence and WAMS scores, but only for male participants. Male participants gave lower ratings of interviewer competence to female than to male interviewers, and ratings for the female interviewers were also lower than those given by female participants. Scores on the WAMS were lower for male participants who were interviewed by a female interviewer than those interviewed by a male interviewer, and were lower for male than for female participants with a female interviewer.