Opioid receptors mediate direct predictive fear learning: evidence from one-trial blocking

Pavlovian fear learning depends on predictive error, so that fear learning occurs when the actual outcome of a conditioning trial exceeds the expected outcome. Previous research has shown that opioid receptors, including μ-opioid receptors in the ventrolateral quadrant of the midbrain periaqueductal gray (vlPAG), mediate such predictive fear learning. Four experiments reported here used a within-subject one-trial blocking design to study whether opioid receptors mediate a direct or indirect action of predictive error on Pavlovian association formation. In Stage I, rats were trained to fear conditioned stimulus (CS) A by pairing it with shock. In Stage II, CSA and CSB were co-presented once and co-terminated with shock. Two novel stimuli, CSC and CSD, were also co-presented once and co-terminated with shock in Stage II. The results showed one-trial blocking of fear learning (Experiment 1) as well as one-trial unblocking of fear learning when Stage II training employed a higher intensity footshock than was used in Stage I (Experiment 2). Systemic administrations of the opioid receptor antagonist naloxone (Experiment 3) or intra-vlPAG administrations of the selective μ-opioid receptor antagonist CTAP (Experiment 4) prior to Stage II training prevented one-trial blocking. These results show that opioid receptors mediate the direct actions of predictive error on Pavlovian association formation.     

Body in Mind: The Role of Embodied Cognition in Self-Regulation

We review a growing body of literature that evidences the reciprocal relationship between body and mind, known as embodied cognition. We argue that an embodied mind may serve a functional purpose, aiding in self-regulatory processes. Specifically, we suggest that embodied cognition assists in self-regulation by increasing signal strength, encouraging appropriate goal-relevant action, and incorporating situational constraints to cue appropriate information processing styles. Furthermore, we propose that affect serves as the link between an embodied mind and self-regulatory action. Finally, we situate this research in debates on theories of mind, and we advocate for a highly interactive system that integrates information across modalities.     

Recruiters’ Inferences of Applicant Personality Based on Resume Screening: Do Paper People have a Personality?

Research shows recruiters infer dispositional characteristics from job applicants’ resumes and use these inferences in evaluating applicants’ employability. However, the reliability and validity of these inferences have not been empirically tested. Using data collected from 244 recruiters, we found low levels of estimated interrater reliability when they reviewed entry-level applicants’ resumes and made inferences regarding applicants’ personality traits. Moreover, when recruiters’ inferences of applicant personality were correlated with applicants’ actual Big Five personality scores, results indicated that recruiters’ inferences lacked validity, with the possible exceptions of extraversion and openness to experience. Finally, despite being largely unreliable and invalid, recruiters’ inferences of applicants’ extraversion, openness to experience, and conscientiousness predicted the recruiters’ subsequent employability assessments of the applicants.     

Impaired embodiment and intersubjectivity

This paper considers the importance of the body for self-esteem, communication, and emotional expression and experience, through the reflections of those who live with various neurological impairments of movement and sensation; sensory deafferentation, spinal cord injury and Möbius Syndrome (the congenital absence of facial expression). People with severe sensory loss, who require conscious attention and visual feedback for movement, describe the imperative to use the same strategies to reacquire gesture, to appear normal and have embodied expression. Those paralysed after spinal cord injury struggle to have others see them as people rather than as people in wheelchairs and have been active in the disability movement, distinguishing between their medical impairment and the social induced disability others project onto them. Lastly those with Möbius reveal the importance of the face for emotional expression and communication and indeed for emotional experience itself. All these examples explore the crucial role of the body as agent for social and personal expression and self-esteem.     

Physical fitness and self-reported physical exercise among college men and women in 1987 and 1997.

The study examined the relations of self-reported physical activity levels and physical fitness scores for two samples of college students assessed in 1987 (n = 261) and in 1997 (n = 243). Significantly greater exercise was reported by the 1997 women than the 1987 women; amount of exercise reported by men did not differ. For both samples, greater exercise was associated with increased fitness for women and men as assessed by the Hall 1986 Physical Fitness Test Profile, comprised of measures on body fat composition; grip strength; muscle endurance, flexibility, resting heart rate; systolic and diastolic blood pressures; and aerobic power. For the 1987 sample men were more fit than women. For the 1997 sample, women were more fit than men. The 1997 women were more fit than the 1987 women; there was no difference on overall fitness measures of the two samples of men.     

Family interaction patterns and childhood depression

Rehm's (1977) self-control model for depression and Bandura's (1977) concept that children internalize external controls placed upon them are united to predict family interaction patterns that may contribute to the etiology or maintenance of depression in children. Families of depressed, nondepressed, and nonclinic children were compared on rates of, and criteria for, parental and self-reinforcement. Mother-father-child interactions were sequentially coded to reveal that mothers of depressed and nonclinic children both set very high criteria for rewarding their children, compared to mothers of clinic/nondepressed children. However, mothers of depressed children rewarded their depressed children at much lower rates than mothers of either clinic/nondepressed or nonclinic children. These factors, taken together, are discussed in terms of their possible etiological role in childhood depression.     

Linking empirically based theory and evaluation: The family bereavement program

Conclusion We have illustrated how our small theory (Lipsey, 1990) of bereavement guided the development and evaluation of a preventive intervention for bereaved children. Our small theory, based on prior empirical research, enabled us to identify family processes that appeared to mediate the effects of parental death on child mental health. Our intervention was designed to attempt to change these processes. The evaluation of our experimental trial of the intervention assessed changes on these processes as well as the more distal mental health outcomes. The experimental trial showed some-what encouraging results, in terms of the program's ability to modify the warmth of the parent–child relationship and to decrease symptomatology in the adolescent children. We also obtained further empirical support for our underlying theoretical model. Finally, implications for redesign of the program were derived from assessing the adequacy of the program components to change each of the mediators in the theoretical model.Support for this research was provided by NIMH grant P5OMH39246 which is gratefully acknowledged. David R. Pillow is now at Western Psychiatric Institute, Pittsburgh; Fred Rogosch is at the University of Rochester; Janette Beals is now at University of Colorado Health Sciences Center; Kim D. Reynolds is now at the University of Alabama, Birmingham; Carl Kallgren is now at the Pennsylvania State University, at Erie; and Rafael Ramirez is now at the University of Puerto Rico.