Spontaneously Hypertensive Rats: Possible Animal Model of Sleep-Related Movement Disorders

Clinical experience suggests that restless legs syndrome (RLS), periodic leg movement (PLM), and attention-deficit hyperactivity disorder (ADHD) may co-occur in both children and adults. The purpose of the present study was to provide an electrocorticography and electromyography evaluation of the spontaneously hypertensive rat (SHR) to investigate the potential of this rat strain as an animal model of RLS–PLM. Initial work focused on evaluating sleep patterns and limb movements during sleep in SHR, having normotensive Wistar rats (NWR) as control, followed by comparison of two treatments (pharmacological–dopaminergic agonist treatment and nonpharmacological–chronic physical exercise), known to be clinically beneficial for sleep-related movement disorders. The captured data strengthen the association between SHR and RLS–PLM, revealing a significant reduction on sleep efficiency and slow wave sleep and an increase on wakefulness and limb movements for the SHR group during the dark period, as compared to the NWR group, effects that have characteristics that are strikingly consistent with RLS–PLM. The pharmacological and nonpharmacological manipulations validated these results. The present findings suggest that the SHR may be a useful putative animal model to study sleep-related movement disorders mechanisms.     

Do adolescents want death to be included in their education?

Social Psychology of Education - This study sets out to ascertain adolescents’ attitudes and opinions towards death education. To this end two instruments were designed and validated: the...     

Who benefits from independent careers? Employees,organizations, or both?

The traditional organizational career has been depicted as the classic example of how employers and employees can develop a mutually beneficial relationship; but changes in the competitive landscape and in individual work values have challenged its viability. Commentators have argued that a ‘new career’ deal, encapsulated by the notions of the protean and the boundaryless career, has emerged suggesting a shift in control of careers from organizations to individuals. Research has explored the implications for individuals' careers while largely neglecting consequences for organizations. Our paper seeks to remedy this by exploring both the individual and the organizational outcomes of independent career orientations and the extent to which organizations can manage these through high commitment human resource management (HRM) practices. Our study, conducted with 655 employee–supervisor dyads, indicates that a protean career orientation results in gains for both employees and organizations, whereas a boundaryless career orientation is associated with mutual losses. In addition, our findings suggest that high commitment HR practices play an important role in managing the outcomes of employees seeking traditional careers but have only a limited impact on those with a boundaryless career orientation.     

Behind the scene: cognitive benefits of playing a musical instrument. Executive functions,processing speed,fluid intelligence and divided attention / Detrás de la escena: beneficios cognitivos de tocar un instrumento musical. Funciones ejecutivas,velocidad de procesamiento,inteligencia fluida y atención dividida

Abstract

The relationship between music training and cognitive performance has been much explored over the last decades. A variety of evidence shows a different neurological and cognitive processing in the population who have undergone instrumental music training compared to people who have not. A review of the literature shows the many advantages in cognitive skills musicians have gained from musical training, such as benefits to their executive functions and other aspects of cognition, in children as well as adults and the elderly. This study investigates in greater depth certain cognitive aspects associated with musical training in the adult population. Specifically, it explores its relationship with inhibition, working memory (verbal and visual-spatial), flexibility, processing speed, fluid intelligence and divided attention. Our results suggest that there is indeed a relationship between musical training and improvements in cognitive performance, both in executive functions and in other areas of cognition.