Adaptive spatial working memory assessments for aging pet dogs

Assessments for spatial working memory (SWM) in pet dogs that can detect age-related cognitive deficits in a single session may aid in diagnosing canine dementia and may facilitate translational research on Alzheimer’s disease in humans. Adaptive testing procedures are widely used in single-session assessments for humans with diverse cognitive abilities. In this study, we designed and deployed two up-down staircase assessments for SWM in which 26 pet dogs were required to recall the location of a treat hidden behind one of two identical boxes following delays of variable length. In the first experiment, performance tended to decline with age but few dogs completed the test (n?=?10). However, all of the dogs that participated in the second experiment (n?=?24) completed the assessment and provided reliable evidence of learning and retaining the task. Delay length and age significantly predicted performance supporting the validity of this assessment. The relationships between age and performance were described by inverted U-shaped functions as both old and young dogs displayed deficits in weighted cumulative-scores and trial-by-trial performance. Thus, SWM in pet dogs may develop until midlife and decline thereafter. Exploratory analyses of non-mnemonic fixation strategies, sustained engagement, inhibitory control, and potential improvements for future SWM assessments which adopt this paradigm are also discussed.

     

Framing a Theological Response to COVID-19 in the Presence of the Religious Other

The Christian faith has a long history of responding to pandemics. Its past practice bore witness to the desire to care for others: it furnished an exemplary model with some notable exceptions. The dilemma that COVID-19 presents is that the understanding of viral spread now lies within the preserve of a professionalized health system. The evident risk as a consequence is one of theological quietism and being “unavailing.” Now is not the time for simple hyper compliance at the expense of an enquiring confessional claim. The ecumenical witness in solidarity with other faiths/religions lends itself to a desire to consider how the present pandemic crisis might serve as an invitation for a theological enquiry into wider planetary issues.     

Racialized Sexual Discrimination (RSD) in the Age of Online Sexual Networking: Are Young Black Gay/Bisexual Men (YBGBM) at Elevated Risk for Adverse Psychological Health?

Young Black gay/bisexual men (YBGBM) are a highly marginalized population across multiple health outcomes. Most research on YBGBM health has focused on HIV/sexual health, but there is a demonstrable need for research examining racism and psychosocial functioning among this population. Racialized Sexual Discrimination (RSD), also known as sexual racism, is an important but under-investigated phenomenon that may have implications for the psychological health and well-being of YBGBM. This paper provides an overview of empirical research on RSD as experienced by gay/bisexual men of color in online partner-seeking venues. First, the researchers discuss how racialized experiences are a documented online phenomenon, with a variety of manifestations, and identify the potential effects that this phenomenon may have on the psychosocial health of YBGBM, and gay/bisexual men of color as a whole. Second, the researchers synthesize the RSD literature with a broader literature examining psychological well-being across race and sexual orientation. Third, the researchers present a theoretically grounded conceptual model detailing the pathways between RSD and psychological well-being using a stress and coping framework. The paper concludes with recommendations for future research on this topic, including scale development and hypothesis testing.     

Validation of the 2012 European Social Survey Measurement of Wellbeing in Seventeen European Countries

The measurement of wellbeing provides an important indicator of the welfare of nations and presents opportunities for policy making. Researchers generally share the view of wellbeing as a multidimensional concept. The 2012 European Social Survey (ESS) measurement of personal and social wellbeing, a combination of theoretical models and evidence from statistical analysis, is defined as a six-dimensional construct: evaluative wellbeing, emotional wellbeing, functioning, vitality, community wellbeing and supportive relationships. In this paper, the proposed theoretical structure is investigated and the psychometric properties of the measure are assessed for 17 European countries. This involved splitting each country’s sample randomly into halves and performing Exploratory Factor Analysis (EFA) on the first half-samples. EFA resulted in a four-factor solution for Germany, Netherlands, Portugal, Slovenia, Spain, Switzerland and the UK, a five-factor solution for Belgium, Finland, France, Ireland, Norway, Poland, Russian Federation and Sweden, and a six-factor solution for Denmark and Hungary. These results were supported by Confirmatory Factor Analysis (CFA) performed on the second half-samples. Subscales were constructed based on analysis of the total samples, applying a simple transformation in order to deal with the different number of response categories used for the wellbeing items. Reliabilities and internal consistencies were investigated. Although the definition of each subscale differs from the proposed structure and across countries, the analysis did produce reliable and valid summary measures (subscales) of wellbeing for informing social policy in each country.

     

From acquisition to consolidation: on the role of brain-derived neurotrophic factor signaling in hippocampal-dependent learning

One of the most rigorously investigated problems in modern neuroscience is to decipher the mechanisms by which experience-induced changes in the central nervous system are translated into behavioral acquisition, consolidation, retention, and subsequent recall of information. Brain-derived neurotrophic factor (BDNF) has recently emerged as one of the most potent molecular mediators of not only central synaptic plasticity, but also behavioral interactions between an organism and its environment. Recent experimental evidence indicates that BDNF modulates synaptic transmission and plasticity by acting across different spatial and temporal domains. BDNF signaling evokes both short- and long-term periods of enhanced synaptic physiology in both pre- and postsynaptic compartments of central synapses. Specifically, BDNF/TrkB signaling converges on the MAP kinase pathway to enhance excitatory synaptic transmission in vivo, as well as hippocampal-dependent learning in behaving animals. Emerging concepts of the intracellular signaling cascades involved in synaptic plasticity induced through environmental interactions resulting in behavioral learning further support the contention that BDNF/TrkB signaling plays a fundamental role in mediating enduring changes in central synaptic structure and function. Here we review recent literature showing the involvement of BDNF/TrkB signaling in hippocampal-dependent learning paradigms, as well as in the types of cellular plasticity proposed to underlie learning and memory.     

Pathways to Risk Among Inner-City African-American Adolescent Females: The Influence of Gang Membership

Differential rates of participation in three categories of risk behaviors (i.e., sexual activity, substance use, violence) were explored, comparing gang members to nonmembers, within a sample of 1,143 inner-city African American adolescent females. The relationship between gang membership and risk behavior also was examined, by exploring the association between a variety of microsystemic influences (e.g., gang, family, school) and participation in risk behaviors. MANOVA analyses indicated that gang members, relative to nonmembers, reported higher rates of participation in each of the three categories of risk behaviors. Stepwise linear regression analyses indicated that gang membership was the variable with the most consistent predictive ability, across all categories of risk, as it entered early in all equations and remained in all three final models after controlling for other statistically significant contextual variables. Findings suggest that intervention efforts aimed at reducing adolescent females' participation in sexual activity, substance use, and violence should consider the influence of gang membership on the participation in these behaviors.     

Familiarity and pronounceability of nouns and names

Ratings of familiarity and pronounceability were obtained from a random sample of 199 surnames (selected from over 80,000 entries in the Purdue University phone book) and 199 nouns (from the Ku?era-Francis, 1967, word database). The distributions of ratings for nouns versus names are substantially different: Nouns were rated as more familiar and easier to pronounce than surnames. Frequency and familiarity were more closely related in the proper name pool than the word pool, although both correlations were modest. Ratings of familiarity and pronounceability were highly related for both groups. A production experiment showed that rated pronounceability was highly related to the time taken to produce a name. These data confirm the common belief that there are differences in the statistical and distributional properties of words as compared to proper names. The value of using frequency and the ratings of familiarity and pronounceability for predicting variations in actual pronunciations of words and names are discussed.