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British attitudes towards Islam and Muslims are examined on the basis of 104 public opinion polls conducted between 1988 and 2006, 90 of them since 2001. Many of these surveys were undertaken at national crisis points of one sort or another for which Islam and Muslims could not avoid being seen as causal factors. Nine high-level conclusions are drawn from this evidence. There has been increasing Islamophobia, not least since 2001. A stereotypical picture of British Muslims in the eyes of the majority population has emerged, Muslims being seen as slow to integrate into mainstream society, feeling only a qualified sense of patriotism, and prone to espouse anti-Western values that lead many to condone so-called Islamic terrorism. To an extent, these stereotypes reflect the reality of Muslim views, as displayed in 29 polls conducted among the British Muslim community, mainly since 2001.  相似文献   
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This study considers the relationship between social competence, sociomoral reasoning, and self‐reported delinquency in a sample of convicted young offenders. Correlations across these factors showed that social competence was significantly related to delinquency. This finding was corroborated by multiple regression, which showed that social competence was the most significant predictor of self‐reported delinquency. Copyright © 1999 John Wiley & Sons, Ltd.  相似文献   
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Although the neuropathology of Korsakoff's syndrome (KS) was first described well over a century ago and the characteristic brain pathology does not pose a diagnostic challenge to pathologists, there is still controversy over the neuroanatomical substrate of the distinctive memory impairment in these patients. Cohort studies of KS suggest a central role for the mammillary bodies and mediodorsal thalamus, and quantitative studies suggest additional damage to the anterior thalamus is required. Rare cases of KS caused by pathologies other than those of nutritional origin provide support for the role of the anterior thalamus and mammillary bodies. Taken together the evidence to date shows that damage to the thalamus and hypothalamus is required, in particular the anterior thalamic nucleus and the medial mammillary nucleus of the hypothalamus. As these nuclei form part of wider memory circuits, damage to the inter-connecting white matter tracts can also result in a similar deficit as direct damage to the nuclei. Although these nuclei and their connections appear to be the primary site of damage, input from other brain regions within the circuits, such as the frontal cortex and hippocampus, or more distant regions, including the cerebellum and amygdala, may have a modulatory role on memory function. Further studies to confirm the precise site(s) and extend of brain damage necessary for the memory impairment of KS are required.  相似文献   
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mRNA translation, or protein synthesis, is a major component of the transformation of the genetic code into any cellular activity. This complicated, multistep process is divided into three phases: initiation, elongation, and termination. Initiation is the step at which the ribosome is recruited to the mRNA, and is regarded as the major rate-limiting step in translation, while elongation consists of the elongation of the polypeptide chain; both steps are frequent targets for regulation, which is defined as a change in the rate of translation of an mRNA per unit time. In the normal brain, control of translation is a key mechanism for regulation of memory and synaptic plasticity consolidation, i.e., the off-line processing of acquired information. These regulation processes may differ between different brain structures or neuronal populations. Moreover, dysregulation of translation leads to pathological brain function such as memory impairment. Both normal and abnormal function of the translation machinery is believed to lead to translational up-regulation or down-regulation of a subset of mRNAs. However, the identification of these newly synthesized proteins and determination of the rates of protein synthesis or degradation taking place in different neuronal types and compartments at different time points in the brain demand new proteomic methods and system biology approaches. Here, we discuss in detail the relationship between translation regulation and memory or synaptic plasticity consolidation while focusing on a model of cortical-dependent taste learning task and hippocampal-dependent plasticity. In addition, we describe a novel systems biology perspective to better describe consolidation.  相似文献   
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Two experimental studies investigated the impact of format and instructions on the validity of SAs, using participants applying for junior management positions in a public sector organization. In Study 1 (607 participants) self-assessments (SAs) were valid when applicants rated overall competencies or the same competencies broken down into discrete elements, but not when providing behavioural evidence prior to rating competencies. The effect of social comparison instructions was also explored but found to have no impact on validity. Study 2 used a subset of 193 candidates from the previous study who attended the next stage of the selection process. Consistent with predictions it was found that unbalanced, positively toned scales were more valid than conventional scales, and highest validities were achieved when used with instructions requesting a realistic SA of strengths and weaknesses. Interestingly, gender differences were found in both studies. These findings are discussed in terms of their implications for both research and practice.  相似文献   
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Clive Erricker 《Topoi》1996,15(2):211-223
Marx and the spiritual dimension  相似文献   
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