Dementia and suicidal behavior

Behavioral and psychological symptoms of dementia, including depression, might complicate the course of the disorder additionally. Dementia is more frequent in older people and suicide rates are higher in later life than in any other age group. To explore the phenomenology of suicidal behavior in patients with dementia, we searched electronic databases and key journals for original research and review articles on suicide in demented patients using the search terms “suicide, suicidal behavior, dementia, Alzheimer disease, and old age”. Although cognitive impairment could result in a diminishing ability to think flexibly and to solve problems or to cope with conflict, in the early stage of dementia such impairments are absent or mild, and suicidal behavior might be expected, especially following diagnosis. In addition, personality changes based on declining cognitive capacity and the neurochemical imbalances described in late-life depression and in dementia may predispose patients to aggressive or impulsive acts, such as suicide attempt. The literature on suicidal behavior and dementia highlights the need for further research in this area.     

On the Ethics of Facial Transplantation Research

Transplantation continues to push the frontiers of medicine into domains that summon forth troublesome ethical questions. Looming on the frontier today is human facial transplantation. We develop criteria that, we maintain, must be satisfied in order to ethically undertake this as-yet-untried transplant procedure. We draw on the criteria advanced by Dr. Francis Moore in the late 1980s for introducing innovative procedures in transplant surgery. In addition to these we also insist that human face transplantation must meet all the ethical requirements usually applied to health care research. We summarize the achievements of transplant surgery to date, focusing in particular on the safety and efficacy of immunosuppressive medications. We also emphasize the importance of risk/benefit assessments that take into account the physical, aesthetic, psychological, and social dimensions of facial disfiguration, reconstruction, and transplantation. Finally, we maintain that the time has come to move facial transplantation research into the clinical phase.     

Multidimensionality of Well-Being and Spillover Effects Across Life Domains: How Do Parenthood and Personality Affect Changes in Domain-Specific Satisfaction?

Whether having children improves our well-being is a long-standing topic of debate. Demographic and sociological research has investigated changes in individuals’ overall well-being and partnership satisfaction when they become parents. However, little is known about how becoming parent may produce vulnerability—observable as an enduring decrease in well-being—in life domains that are strongly interdependent with the family domain, such as work and leisure. Linking life-course and personality psychology perspectives, the authors examine the trajectories of subjective well-being—measured as satisfaction with life, work, and leisure—3 years before and 3 years after the transition to parenthood. The authors particularly focus on the moderating effects of gender and personality. Using data from the German Socio-Economic Panel (1984–2013) and multilevel growth curve modeling, the authors show strong gender-based vulnerability in how people react to parenthood. Although men display a nonlinear pathway of decreasing life satisfaction and a stable trajectory of job satisfaction, women experience more changes in their satisfaction with work and more dramatic decreases in leisure satisfaction. Contrary to most of our expectations, the moderating effects of personality were modest. Extraversion influenced the trajectories of work satisfaction, whereas neuroticism and conscientiousness affected the pathway of leisure satisfaction for women only. This article shows that the transition to parenthood influences well-being trajectories in specific domains, and this influence differs between women and men.     

Implicit chord processing and motor representation in pianists

The aim of this paper is to assess the relevance of pitch dimension in auditory–motor interaction. Several behavioural and brain imaging studies have shown that auditory processing of sounds can activate motor representations, an effect which is however elicited only by action-related sounds, i.e., sounds linked to a specific motor repertoire. Music provides an appropriate framework for further exploration of this issue. Three groups of participants (pianists, non-pianist musicians and non-musicians) were tested with a shape decision task where left-hand and right-hand responses were required; each visual stimulus was paired with an auditory task-irrelevant stimulus (high-pitched or low-pitched piano-timbre chords). Of the three groups, only pianists had longer reaction times for left-hand/high-pitched chords and right-hand/low-pitched chords associations. These findings are consistent with an auditory-motor effect elicited by pitch dimension, as only pianists show an interaction between motor responses and implicit pitch processing. This interaction is consistent with the canonical mapping of hand gestures and pitch dimension on the piano keyboard. The results are discussed within the ideo-motor theoretical framework offered by the Theory of Event Coding (Hommel et al. in Behav Brain Sci 24:849–937, 2001).     

Development of infant prehension handedness: A longitudinal analysis during the 6- to 14-month age period

Handedness is a developmental phenomenon that becomes distinctively identifiable during infancy. Although infant hand-use preferences sometimes have been reported as unstable, other evidence demonstrates that infant hand-use preference for apprehending objects can be reliably assessed during the second half of the infant's first year of life. The current study provides further insight into the stability of prehension preferences. We modeled individual and group level patterns of prehension handedness during the period from 6 to 14 months of age. We examined the developmental trajectories for prehension handedness in relation to the sampling rate at which preferences are assessed. The results revealed interesting developmental changes in prehension handedness that can only be identified when using monthly sampling intervals. We conclude that using non-linear multilevel models of infant handedness with monthly sampling intervals permit us to accurately capture the developmental changes in manual skills that occur during this period of infancy.     

Generalised Reichenbachian common cause systems

The principle of the common cause claims that if an improbable coincidence has occurred, there must exist a common cause. This is generally taken to mean that positive correlations between non-causally related events should disappear when conditioning on the action of some underlying common cause. The extended interpretation of the principle, by contrast, urges that common causes should be called for in order to explain positive deviations between the estimated correlation of two events and the expected value of their correlation. The aim of this paper is to provide the extended reading of the principle with a general probabilistic model, capturing the simultaneous action of a system of multiple common causes. To this end, two distinct models are elaborated, and the necessary and sufficient conditions for their existence are determined.