Neurodevelopmental model of long-term outcomes of adult survivors of childhood brain tumors

Childhood brain tumors and related treatments disrupt the developing brain and have a cascading impact on core cognitive skills and intellectual (intelligence quotient [IQ]) and academic achievement outcomes. Theoretical models for this cascade have been developed based on the literature, but no studies thus far have empirically evaluated the models. The current study aimed to empirically test the two extant models and generate a new data-driven model of the relationships among neurodevelopmental risk factors, core cognitive skills (i.e., processing speed, attention span, working memory), and IQ and achievement outcomes. Fifty-seven adult survivors of childhood brain tumors and fifty-seven demographically matched neurotypical individuals were included in the current study. The average age at brain tumor diagnosis was 8 years, and the average time since diagnosis was 17 years. Three a priori path models tested the hypothesized relationships among variables. Results of the path analyses revealed that the hybrid model best fit the data for both survivors and controls based on all statistical criteria. For survivors, processing speed was the core cognitive skill most widely associated with neurodevelopmental risk factors and outcomes. However, working memory and attention span also had unique contributions to IQ and academic achievement. Processing speed appears to be the central cognitive skill that disrupts the other core cognitive skills of attention span and working memory, and all three make a unique contribution to IQ and academic achievement. This is best demonstrated by a novel neurodevelopmental model that combines components of two earlier untested theoretical models.     

Imperatives: a Judgemental Analysis

This paper proposes a framework for formalising intuitions about the behaviour of imperative commands. It seeks to capture notions of satisfaction and coherence. Rules are proposed to express key aspects of the general logical behaviour of imperative constructions. A key objective is for the framework to allow patterns of behaviour to be described while avoiding making any commitments about how commands, and their satisfaction criteria, are to be interpreted. We consider the status of some conundrums of imperative logic in the context of this proposal.     

Maternal Over-Control Moderates the Association Between Early Childhood Behavioral Inhibition and Adolescent Social Anxiety Symptoms

Behavioral inhibition (BI) and maternal over-control are early risk factors for later childhood internalizing problems, particularly social anxiety disorder (SAD). Consistently high BI across childhood appears to confer risk for the onset of SAD by adolescence. However, no prior studies have prospectively examined observed maternal over-control as a risk factor for adolescent social anxiety (SA) among children initially selected for BI. The present prospective longitudinal study examines the direct and indirect relations between these early risk factors and adolescent SA symptoms and SAD, using a multi-method approach. The sample consisted of 176 participants initially recruited as infants and assessed for temperamental reactivity to novel stimuli at age 4?months. BI was measured via observations and parent-report across multiple assessments between the ages of 14?months and 7?years. Maternal over-control was assessed observationally during parent–child interaction tasks at 7?years. Adolescents (ages 14–17?years) and parents provided independent reports of adolescent SA symptoms. Results indicated that higher maternal over-control at 7?years predicted higher SA symptoms and lifetime rates of SAD during adolescence. Additionally, there was a significant interaction between consistently high BI and maternal over-control, such that patterns of consistently high BI predicted higher adolescent SA symptoms in the presence of high maternal over-control. High BI across childhood was not significantly associated with adolescent SA symptoms when children experienced low maternal over-control. These findings have the potential to inform prevention and early intervention programs by indentifying particularly at-risk youth and specific targets of treatment.     

Hedges enhance memory but inhibit retelling

We examined the effects of hedges and the discourse marker like on how people recalled specific details about precise quantities in spontaneous speech. We found that listeners treated hedged information differently from like-marked information, although both are thought to be indicators of uncertainty or vagueness. In addition, hedges had different effects depending on whether speakers were (1) retelling conversations to another person or (2) answering questions about material they had heard. When retelling to another person, listeners were more likely to report information that was either unmarked or marked with a like than hedged information (Experiment 1). Yet when answering questions by themselves, hedges enhanced memory for details, in comparison with likes (Experiment 2). Hedges appear to provide pragmatic cues about what information is reliable enough to repeat in a conversational context. But although hedged information may be left out, it is not forgotten.     

Event-related potential practice effects on the Paced Auditory Serial Addition Test (PASAT)

Practice can change the nature and quality of a stimulus-response relationship. The current study observed the effects of repeated administration of the Paced Auditory Serial Addition Test (PASAT) in 12 healthy individuals, in an effort to establish distinct profiles associated with novel and practiced processing. Over four training sessions the mean number of correct responses on this demanding test of attention significantly improved and was approaching ceiling for most task conditions. Behavioural improvements were associated with significantly reduced amplitude of late Processing Negativity, a frontally distributed component of the event-related potential waveform associated with voluntary, limited-capacity activity within higher-order attentional systems. These results suggest that PASAT performance became more efficient as practice seemingly eased the strategic planning and coordination requirements the task places on frontally-mediated executive attention resources. The findings of the current study extend our understanding of the functional and behavioural mechanisms underlying the effects of practice.     

Compensatory and non‐compensatory multidimensional randomized item response models

Randomized response (RR) models are often used for analysing univariate randomized response data and measuring population prevalence of sensitive behaviours. There is much empirical support for the belief that RR methods improve the cooperation of the respondents. Recently, RR models have been extended to measure individual unidimensional behaviour. An extension of this modelling framework is proposed to measure compensatory or non‐compensatory multiple sensitive factors underlying the randomized item response process. A confirmatory multidimensional randomized item response theory model (MRIRT) is proposed for the analysis of multivariate RR data by modelling the response process and specifying structural relationships between sensitive behaviours and background information. A Markov chain Monte Carlo algorithm is developed to estimate simultaneously the parameters of the MRIRT model. The model extension enables the computation of individual true item response probabilities, estimates of individuals’ sensitive behaviour on different domains, and their relationships with background variables. An MRIRT analysis is presented of data from a college alcohol problem scale, measuring alcohol‐related socio‐emotional and community problems, and alcohol expectancy questionnaire, measuring alcohol‐related sexual enhancement expectancies. Students were interviewed via direct or RR questioning. Scores of alcohol‐related problems and expectancies are significantly higher for the group of students questioned using the RR technique. Alcohol‐related problems and sexual enhancement expectancies are positively moderately correlated and vary differently across gender and universities.     

EFFECTS OF KANGAROO MOTHER CARE ON MATERNAL MOOD AND INTERACTION PATTERNS BETWEEN PARENTS AND THEIR PRETERM,LOW BIRTH WEIGHT INFANTS: A SYSTEMATIC REVIEW

The birth of a premature infant can have adverse effects on the mood of mothers and on the interaction patterns between parents and their preterm babies. The aim of the present systematic review was to examine whether the Kangaroo Mother Care (KMC) intervention can attenuate these adverse psychological effects of a premature birth by ameliorating negative maternal mood and/or promoting more positive interactions between preterm infants and their parents. The results showed that although findings of studies were inconclusive, there is some evidence to suggest that KMC can make a positive difference on these areas. Specifically, it was found that KMC can improve negative maternal mood (e.g., anxiety or depression) and promote more positive parent–child interactions. Limitations and directions for future research are discussed.     

Advice for Plagiarism Whistleblowers

Scholarly open-access publishing has made it easier for researchers to discover and report academic misconduct such as plagiarism. However, as the website Retraction Watch shows, plagiarism is by no means limited to open-access journals. Moreover, various web-based services provide plagiarism detection software, facilitating one’s ability to detect pirated content. Upon discovering plagiarism, some are compelled to report it, but being a plagiarism whistleblower is inherently stressful and can leave one vulnerable to criticism and retaliation by colleagues and others (Anderson, 1993; Cabral-Cardoso, 2004). Reporting plagiarism can also draw the threat of legal action. This article draws upon our experiences as plagiarism whistleblowers with several goals in mind: to help would-be whistleblowers be better prepared for making well-founded allegations, to give whistleblowers some idea of what they can expect when reporting plagiarism, and to give suggestions for reducing whistleblowers’ vulnerability to threats and stress.     

Religion,ethnicity, coping style,and self-reported self-harm in a diverse non-clinical UK population

Previous studies of ethnic and cultural differences in self-harm have focussed on overdose and suicide attempts by South Asian women. Research comparing ethnic groups has rarely examined religion or nationality. To achieve a more balanced approach this study examined self-harm methods and self-injury across gender, religion and ethnic group in a non-clinical population. Six hundred and seventeen university students completed a questionnaire asking whether they had ever harmed themselves, and the frequency and method of any self-harm. White participants and participants with no religious affiliation were more likely to report repeated incidents of self-harm, mainly scratching and cutting skin. Hindu religion was associated with lower levels of repeated self-harm. Asian males were less likely to report self-harm than both Asian females and other males. Black students were less likely to report cutting and scored highest on Rational coping style. The results raise questions about differential disclosure of self-harm across gender and culture.