Health Beliefs and Behaviors of Women Who Have Received Genetic Counseling For Breast Cancer

There are both genetic and behavioral risk factors for breast cancer, but the interaction between these factors is not clear. Little is known about the impact of receiving genetic risk information for breast cancer on behaviors such as diet and physical activity. Seven focus groups were conducted with 23 women who had recently received genetic counseling for breast cancer, in order to explore health beliefs and behaviors following genetic counseling. Findings revealed that there was much confusion and uncertainty about the associations between health behaviors and breast cancer risk, and participants reported that receiving genetic counseling had little impact on health protective behaviors. Further research is required to understand variation in response to genetic risk information, and to assess the impact of providing additional information regarding lifestyle factors.     

Stigmatization,Culture and Counseling A Commentary on Growing Up and Living with NF1: a UK–Bangladeshi Case Study—by Santi Rozario

Rozario's presentation of the cultural manifestations of stigma experienced by a British Bangladeshi woman with Neurofibromatosis 1 (NF1) is unusual in its detail of one woman's account of others' interactions with her and the impact on her life. It raises issues that are readily recognisable to genetic counselors and are familiar themes in the literature on the psychology of appearance. We draw on the genetics literature and on a body of expertise in research on the psychology of visible difference to consider the role of the genetic counselor in response to expressions of stigmatization or poor self-esteem by those with a visible difference caused by a genetic condition.     

Assessing self-critical perfectionism in clinical depression

Several facets of perfectionism have been strongly associated with depression and anxiety. Dunkley and Blankstein (2000) combined these maladaptive traits with self-criticism to create a general construct labeled self-critical perfectionism. In this study, we employed confirmatory factor analysis to evaluate a model for assessing self-critical perfectionism in a clinically depressed sample using scales from 3 instruments. Participants were 356 depressed adult outpatients who completed 2 multidimensional measures of perfectionism and a measure of self-criticism. A confirmatory factor model that separated a self-critical perfectionism construct from a more adaptive, achievement-striving component of perfectionism was supported. A composite scale assessing self-critical perfectionism demonstrated much larger correlations with distress measures compared to a composite scale assessing achievement striving and also showed evidence of discriminant validity. In this study, we provided further support for the valid assessment of self-critical perfectionism and extended evidence for its assessment to a clinically depressed sample.     

Chicks prefer to peck at insect-like elongated stimuli moving in a direction orthogonal to their longer axis

Spontaneous preferences towards possible prey have been little investigated using targets in motion. Preferences of domestic chicks (Gallus gallus) to peck at video-images of stimuli representing live insects moving along their longer body axis (i.e. “forwards”) or along the shorter body axis (i.e. “sideways”) were investigated. Chicks presented with both types of stimulus displayed a significant preference for pecking at stimuli moving sideways. This preference was already present on day 1 post-hatching, and it strengthened on day 6 for those chicks that had experienced pecking at live insects. Head angles used to fixate the stimuli prior to pecking were also analysed and were consistent (i.e. 30°–35° and 60°–65°) with those reported for fixation of non-edible targets (larger stimuli at a distance). In a first control experiment the same video-presented stimuli were used but the insect’s legs were removed to reduce flickering. In a second control experiment, paper-printed images of the whole insect were used. In both cases, the sideways direction of movement was clearly preferred. Overall, our data show that chicks have a spontaneous preference to peck at video-images resembling live insects moving along their shorter body axis. Sideways movement may constitute a crucial signal attracting chicks’ attention and enhancing predatory responses possibly because of stronger stimulation of motion detectors.     

Determinants of Quality of Life in Pre-Frail Older Adults According to Phenotypic Criteria: the VERISAUDE Study

Frailty is a dynamic clinical syndrome considered as part of an age-associated continuum of severity, including pre-frailty as an intermediate frailty status with potential reversibility to robustness. The main purpose of this study was to analyse the relationship between the different domains of quality of life, functional dependence and depressive symptomatology in older adults diagnosed as pre-frail, before progression to frailty occurs. Logistic regression analyses were conducted to examine whether sex, age, level of education and scores in the Geriatric Depression Scale 15-item Short Form (GDS-SF) and the Instrumental Activities of Daily Living Lawton scale determine the worst score in the WHOQOL-BREF (World Health Organization Quality of Life) in older adults meeting one or two frailty phenotypic criteria. Depressive symptomatology (GDS-SF score) was the main determinant of poor quality of life in both groups, and in all areas of WHOQOL-BREF. Age was only associated with poor satisfaction with own health. Female sex and low educational level were linked to low physical QOL and poor self-rated health, respectively, but only in older adults meeting one frailty criterion. Association between functional status and WHOQOL-BREF scores was only found in the univariate analysis. These results underline the importance of identifying multiple aspects, but mainly the presence of depressive symptomatology, as risk factors for all dimensions of quality of life in the pre-frailty process, where interventions might be targeted to reduce the progression of pre-frailty and frailty in older adults.     

Domestic chicks perceive stereokinetic illusions

Stereokinetic illusions occur when certain 2-D patterns are set in slow rotation in a plane perpendicular to the line of sight. Such phenomena have never been investigated in animal species other than our own. We used the domestic chick (Gallus gallus) to check whether these illusions are experienced by non-human species, taking advantage of filial imprinting. Newly hatched visually naive chicks were individually exposed for 4 h to 2-D stimuli producing, to a human observer, the perception of a stereokinetic cone (experiment 1) or of a stereokinetic cylinder (experiment 2). Thereafter, each chick underwent a free-choice test between a solid 3-D cone and a solid 3-D cylinder. A control group of newly hatched but not imprinted chicks underwent the same testing procedure, to check for the presence of any spontaneous preference for one or other of the two solid objects. Imprinted chicks approached the 3-D stimulus closely resembling the stimulus they had been exposed to during imprinting (the cone in experiment 1 and the cylinder in experiment 2). Non-imprinted chicks did not show any preference. These results suggest that domestic chicks experience stereokinetic illusions.     

Predictive Testing of Eighteen Year Olds: Counseling Challenges

Genetic counseling of teenagers is challenging and complex. The ability to think abstractly, a sense of self and independence from family all develop during adolescence. Predictive genetic testing counseling protocols presuppose that these qualities exist, requiring the at-risk individual to consider the short and long term consequences of testing as well as their motivations. Eighteen year olds are in transition from adolescence to adulthood; eligible for predictive genetic testing, they may not yet be independent of their family or able to articulate their feelings. This paper presents case studies from the authors' clinical practice to illustrate some of the difficulties faced by genetic counselors when 18 year olds request predictive testing for Hereditary Non-Polyposis Colorectal Cancer. By reflecting upon their experiences with these young adults and their families, the authors' intention is to generate discussion about genetic counseling strategies, particularly for predictive genetic testing, that are both age-appropriate and family-sensitive.     

Simultaneous multiple stressors in the environment: physiological stress reactions, performance, and stress evaluation

Interactive effects of two environmental stressors when simultaneous ly present, i.e., noise and crowding, were analyzed. Four experimental conditions with two intensities of stress for each stressor (high versus low) were created. The stressors were concurrently introduced in laboratory conditions and their effects analyzed using several methodological approaches. More intense and negative effects were expected when the two highest intensities of noise and crowding concurred. 40 people (20 men and 20 women) participated in a study with a 2 x 2 factorial design. Analysis showed an increase in the measures of hemodynamic, endocrine, and neuroendocrine values of participants after being exposed simultaneously to noise and crowding. Similarly, their performance on complex tasks decreased, and they reported a subjective increase in stress. Capacity to cope was indicated by a statistically significant lower mean on the Dimension of Stress scale, tolerance of frustration during the multiple stress condition.     

The influence of contrast and spatial factors in the perceived shape of boundaries

When an edge can be perceived to continue either with a collinear edge of the opposite contrast polarity or with a noncollinear edge of the same contrast polarity, observers perceive an alignment between the edges of the same contrast polarity, even though they are noncollinear. Using several stimulus configurations and both free and tachistoscopic viewing, we studied the luminance and spatial factors affecting the perceived distortion and binding. The results showed that the two noncollinear edges tended to align when they had the same contrast polarity (Experiment 1A) and to misalign when they had opposite contrast polarity (Experiment 2), providing that (1) they were separated by a distance larger than 1 arcmin and smaller than 3-4 arcmin (for all configurations) and (2) they laterally overlapped for about 7 arcmin (Experiment 1B). The results also showed that the direction of apparent distortion depended on the direction of overlapping. The results of Experiment 3 ruled out the local attraction/repulsion explanation but, instead, supported the suggestion that the interaction concerned the global edges, or part of them, and produced an inward tilt, which made the edges of the same contrast polarity perceptually to align, or an outward tilt, so that the edges of opposite contrast polarity were perceived to be more misaligned. From the overlap and distance limits found, it can be inferred that for two noncollinear contours to join perceptually, the tilt must not exceed 18 degrees, a limit compatible with the orientation bandwidth of contrast-sensitive early cortical mechanisms.     

Alcohol-related knowledge and attitudes in people with a mild learning disability – the effects of a ‘sensible drinking’ group

Alcohol-related knowledge and attitudes in people with a mild learning disability, who were either living, or being prepared to live, in relatively independent conditions in the community, were assessed through a structured interview format. Compared with non-learning-disabled teenagers, adults and a hospitalized patient sample, alcohol-related knowledge in the people with a learning disability was found to be significantly poorer, alcohol was reported as having particularly negative effects and susceptibility to social pressure to drink alcohol was greater. A ‘sensible drinking’ group, taking a social skills and influences approach to alcohol education, was conducted with a subgroup of the individuals with a learning disability. The group format and methods, including in vivo sessions in a public house, are described. Follow-up evaluations suggested some significant positive changes in knowledge, attitudes and sensible drinking skills. It is concluded that this population, which is increasingly living, or being moved into, independent conditions in the community, is at least as vulnerable to social influences on alcohol use and abuse as are young people. As with young people, the usefulness of making available such alcohol-education programmes as described in this study, is discussed.