An analysis of some sensitizing agents in the pathogenesis of stress-induced gastric erosive disease

Prior surgical implantation of a venous catheter sensitized rats to coldimmobilization stress. Three of six catheterized females succumbed during the stress. The remaining rats fell into two groups in terms of their core temperature at the end of the stress period: Male uncatheterized rats had higher temperatures than rats in the other three groups. No relation was found between catheter patency and magnitude of hypothermia. Degree of gastric disease paralleled the core temperature findings in that the male uncatheterized rats had significantly fewer gastric erosions than the rats in the other three groups. Additionally, a robust effect of gender was found with uncatheterized females showing more hypothermia and more gastric disease than uncatheterized males. A subsequent experiment was conducted to evaluate whether anesthesia or wearing the protective spring was responsible in part for the sensitization seen. Here, the gender difference was less although females consistently averaged lower core temperatures after stress than did males. Despite similar core temperatures after stress, females that were prepared with the protective spring apparatus developed more gastric disease than female controls or similarly treated males. Thus, the additional sensitization exhibited by females in the first experiment may relate to the fact that both catheterization and the taping procedure were sensitizers while only catheterization was a sensitizer for males.     

The effects of ethanol intoxication on phobic anxiety

Behavioral conceptions of alcohol abuse often include the hypothesis that drinking behavior is a negatively reinforced operant, with ethanol intoxication viewed as alleviating aversive environmental and internal states. This hypothesis has not been confirmed or refuted by previous studies which employed mild stressors and limited assessment methodology. In the present experiment, 22 patients with severe phobias approached their phobic animal under two consecutive conditions—first while sober and second after drinking either a placebo or an intoxicating dose of ethanol. The severe anxiety induced was assessed behaviorally, physiologically and by the patient's self-report of fear. The intoxicated patients did not experience decreased anxiety, tachycardia or avoidance, compared to the placebo group. These results have clinical implications and suggest the need to reconsider tension-reduction theories of alcohol abuse.     

TRAINING AND GENERALIZATION OF REACH-GRASP BEHAVIOR IN BLIND,RETARDED YOUNG CHILDREN

The effects of a graduated prompting treatment procedure were analyzed in three phases of an experiment on the training and generalization of reaching-grasp responding in 2- to 4-year-old blind, severely or profoundly retarded children. In Phase 1, we used a multiple-baseline across-subjects design to investigate the effectiveness of the treatment on midline reach-grasp responding. In Phase 2, we used a reversal design to investigate the effects of repeated implementations and withdrawals of the treatment. In both phases, generalization to right and left positions was measured. In Phase 3, in a multiple-baseline across-responses design, the treatment was implemented in right and left positions. Also in Phase 3, shift of stimulus control from toy-sound to verbal instructions was measured. The results showed that (a) the graduated prompting procedure was effective in training reach-grasp responding in all three children; (b) for one child, the effects were durable over repeated applications of the treatment procedure, but were not maintained during withdrawals; (c) for another child, the treatment procedure was effective in teaching reach-grasp responding in all three positions; and (d) for the same child, training of reach-grasp responding generalized to toys presented without sound, given only the verbal instruction.     

Development of sex biases in children: 40 years later

Children in grades 2–10 (200 of each sex) assigned desirable and undesirable traits to girls or boys. Half the subjects had an additional option of both sexes. Children in all grades assigned more desirable traits to their own sex and more undesirable traits to the opposite sex, in line with Smith (1939). Both sexes became less positive toward their own sex and more positive toward the opposite sex with increasing age. This pattern also had characterized girls in Smith's study, whereas, boys had shown the opposite pattern. Beginning in the sixth grade, girls were more apt than boys to assign desirable traits to their own sex. Availability of the “both sexes” option decreased stereotyping, especially in girls.     

Sexism and beautyism in women's evaluations of peer performance

The purpose of this study was to investigate independent and interactive effects of physical attractiveness (PA), sex, and task sex-typing on performance evaluations. Subjects were 216 college women who read poorquality essays written on masculine, feminine, or neutral topics. Essays supposedly were written by a male or a female student who was either attractive, unattractive, or physically unidentified. Results indicated that PA enhanced evaluations of both male and female essayists, except for the predicted effect that female attractiveness is less beneficial for masculine than feminine task performances. Women did not evaluate the sexes differently, and sexism was largely restricted to the interactive effects of PA. PA stereotypes also affected causal attributions of performers' outcomes in a manner consistent with attribution theory. These data are considered in the context of the existing literature and the directions for further research on sexism and beautyism.     

The Most Important Election of Our Lifetime: Focalism and Political Participation

This article argues that a psychological bias called “focalism” contributes to an overestimation of the differences between political candidates, which in turn increases participation and polarization. Focalism causes people to confuse the allocation of attention to things with the importance of those things. Because attention to politics typically centers on conflict, the result is an exaggeration of differences across the partisan divide. I test this intuition using an experimental design that provides all respondents with all the information they need to estimate how much Joe Biden and Donald Trump objectively disagreed on policy positions just before the 2020 election. I find that shifting attention—toward either those positions the candidates agreed or disagreed with each other on—influences beliefs about the differences between candidates. The effect exceeds that of identifying as a Democrat or as a Republican. Beyond those perceptions, focalism increases turnout intentions, perceptions of election importance, negative feelings towards the out-candidate, and affective polarization.     

Nietzsche and “we knowers”: Comments on Reginster's The Will to Nothingness

Nietzsche's On the Genealogy of Morality is strikingly book-ended by the theme of knowledge-seeking: the Preface opens with the ominous claim that “[w]e are unknown to ourselves, we knowers”, and the Third Essay's climax is the assertion that scientific, scholarly activity does not stand in opposition to the ascetic ideal but is instead only that ideal's most recent and insidious instantiation. This feature of the text is absent from Reginster's The Will to Nothingness. Nonetheless, the interpretive machinery that Reginster develops in his reading of the Genealogy as a genealogy and critique of morality can also go a long way towards helping us to make sense of the text as, at the same time, a genealogy and critique of knowledge-seeking. Making use of Reginster's account in this way serves to illuminate both the interpretive power and some of the limitations of his reading.     

Direct quantitative judgments of sums and a two-stage model for psychophysical judgments

Judged magnitudes of differences between stimuli have previously been shown to support a two-stage interpretation of magnitude estimation, in which input transformations and output transformations are each describable as power functions. In an effort to provide support for the model independent of the difference estimation procedure. the present investigation employed two additional judgment tasks. We obtained magnitude judgments and category judgments of the combined magnitudes (sums) of paired weights from two groups of Ss. Values of the inferred input exponent k calculated from the two sets of data were very similar and were also remarkably similar to the exponent previously calculated from magnitude estimations of differences between weights. The output exponent calculated from magnitude judgments of sums described a concave upward function; however. the similar function describing category judgments was essentially linear. These results show that the inferred input exponent is not the result of the difference estimation task, and in addition provides support for the contention that the interval scale may be a less biased sensory measure than the magnitude scale. The introduction of an additive constant to the model improved its fit to the data but the rule by which it was introduced made very little difference.