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251.
Exposure to severe air pollution produces neuroinflammation and structural brain alterations in children. We tested whether patterns of brain growth, cognitive deficits and white matter hyperintensities (WMH) are associated with exposures to severe air pollution. Baseline and 1 year follow-up measurements of global and regional brain MRI volumes, cognitive abilities (Wechsler Intelligence Scale for Children-Revised, WISC-R), and serum inflammatory mediators were collected in 20 Mexico City (MC) children (10 with white matter hyperintensities, WMH+, and 10 without, WMH) and 10 matched controls (CTL) from a low polluted city. There were significant differences in white matter volumes between CTL and MC children - both WMH+ and WMH - in right parietal and bilateral temporal areas. Both WMH and WMH+ MC children showed progressive deficits, compared to CTL children, on the WISC-R Vocabulary and Digit Span subtests. The cognitive deficits in highly exposed children match the localization of the volumetric differences detected over the 1 year follow-up, since the deficits observed are consistent with impairment of parietal and temporal lobe functions. Regardless of the presence of prefrontal WMH, Mexico City children performed more poorly across a variety of cognitive tests, compared to CTL children, thus WMH+ is likely only partially identifying underlying white matter pathology. Together these findings reveal that exposure to air pollution may perturb the trajectory of cerebral development and result in cognitive deficits during childhood.  相似文献   
252.
Genetic counseling and testing for hereditary breast cancer have the potential benefit of early detection and early interventions in African American women. However, African American women have low use of these services compared to White women. We conducted two focus groups with African American women diagnosed with breast cancer (affected group, n?=?13) and women with at least one first-degree relative with breast/ovarian cancer (unaffected group, n?=?8). A content analysis approach was employed to analyze interview data. Breast cancer survivors had more knowledge about genetic counseling and testing than participants who were unaffected with cancer. However, knowledge about genetic counseling was limited in both groups. Barriers to pursuing genetic counseling and testing included poor understanding of the genetic counseling and testing process, fear of carrying the mutation, concerns about discrimination, and cost. Motivators to participate in genetic counseling and testing included desire to help family members, insurance coverage, and potential of benefiting the larger African American community. Education efforts are needed to increase genetic counseling and testing awareness in the African American community.  相似文献   
253.
Slepian, Masicampo, Toosi, and Ambady (Journal of Experimental Psychology: General, 141, 619–624, 2012, Study 1) found that individuals recalling and writing about a big, meaningful secret judged a pictured hill as steeper than did those who recalled and wrote about a small, inconsequential secret (with estimates unrelated to physical effort unaffected). From an embodied cognition perspective, this result was interpreted as suggesting that important secrets weigh people down. Answering to mounting calls for the crucial need of independent direct replications of published findings to ensure the self-correcting nature of our science, we sought to corroborate Slepian et al.’s finding in two extremely high-powered, preregistered studies that were very faithful to all procedural and methodological details of the original study (i.e., same cover story, study title, manipulation, measures, item order, scale anchors, task instructions, sampling frame, population, and statistical analyses). In both samples, we were unsuccessful in replicating the target finding. Although Slepian et al. reported three other studies supporting the secret burdensomeness phenomenon, we advise that these three other findings need to be independently corroborated before the general phenomenon informs theory or health interventions.  相似文献   
254.
The perception of event structure in continuous activity is important for everyday comprehension. Although the segmentation of experience into events is a normal concomitant of perceptual processing, previous research has shown age differences in the ability to perceive structure in naturalistic activity, such as a movie of someone washing a car. However, past research has also shown that older adults have a preserved ability to comprehend events in narrative text, which suggests that narrative may improve the event processing of older adults. This study tested whether there are age differences in event segmentation at the intersection of continuous activity and narrative: narrative film. Younger and older adults watched and segmented a narrative film, The Red Balloon, into coarse and fine events. Changes in situational features, such as changes in characters, goals, and objects predicted segmentation. Analyses revealed little age-difference in segmentation behavior. This suggests the possibility that narrative structure supports event understanding for older adults.  相似文献   
255.
Journal of Business and Psychology - Receiving social support is widely considered a positive workplace phenomenon, but what about the employees from whom the support is being sought? Following...  相似文献   
256.
Journal of Business and Psychology - Numerous advancements have been made regarding how aspects of job roles and organizational environments affect work attitudes. However, less attention has been...  相似文献   
257.
Research on Child and Adolescent Psychopathology - Emotion dysregulation has been posited as a key transdiagnostic factor of mental health difficulties, including eating disorders. However, how...  相似文献   
258.
Research on Child and Adolescent Psychopathology - Externalizing behaviors are associated with poor academic outcomes in community-based samples of children as young as preschool-age. However,...  相似文献   
259.
Journal of Clinical Psychology in Medical Settings - Limited scalability combined with limited opportunities for patients to receive evidence-based interventions in traditional behavioral health...  相似文献   
260.
Cognitive Processing - Memory impairment following an acquired brain injury can negatively impact daily living and quality of life—but can be reduced by memory rehabilitation. Here, we review...  相似文献   
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