Transient hippocampal down-regulation of Kv1.1 subunit mRNA during associative learning in rats

Voltage-gated potassium channels (Kv) are critically involved in learning and memory processes. It is not known, however, whether the expression of the Kv1.1 subunit, constituting Kv1 channels, can be specifically regulated in brain areas important for learning and memory processing. Radioactive in situ hybridization was used to evaluate the content of Kv1.1 α-subunit mRNA in the olfactory bulb, ventral, and dorsal hippocampus at different stages of an odor-discrimination associative task in rats. Naive, conditioned, and pseudoconditioned animals were sacrificed at different times either prior to a two-odor significance learning or after odor discrimination was established. Important decreases of Kv1.1 mRNA levels were transiently observed in the ventral hippocampus before successful learning when compared with the pseudoconditioned group. Moreover, temporal group analysis showed significant labeling alterations in the hippocampus of conditioned and pseudoconditioned groups throughout the training. Finally, Kv1.1 mRNA levels in the hippocampus were positively correlated with odor-reward association learning in rats that were beginning to discriminate between odors. These findings indicate that the Kv1.1 subunit is transiently down-regulated in the early stages of learning and suggest that Kv1 channel expression regulation is critical for the modification of neuronal substrates underlying new information acquisition.     

Manipulating perception versus action in recalibration tasks

We conducted six experiments to examine how manipulating perception versus action affects perception–action recalibration in real and imagined blindfolded walking tasks. Participants first performed a distance estimation task (pretest) and then walked through an immersive virtual environment on a treadmill for 10 min. Participants then repeated the distance estimation task (posttest), the results of which were compared with their pretest performance. In Experiments 1a, 2a, and 3a, participants walked at a normal speed during recalibration, but the rate of visual motion was either twice as fast or half as fast as the participants' walking speed. In Experiments 1b, 2b, and 3b, the rate of visual motion was kept constant, but participants walked at either a faster or a slower speed. During pre- and posttest, we used either a blindfolded walking distance estimation task or an imagined walking distance estimation task. Additionally, participants performed the pretest and posttest distance estimation tasks in either the real environment or the virtual environment. With blindfolded walking as the distance estimation task for pre- and posttest, we found a recalibration effect when either the rate of visual motion or the walking speed was manipulated during the recalibration phase. With imagined walking as the distance estimation task, we found a recalibration effect when the rate of visual motion was manipulated, but not when the walking speed was manipulated in both the real environment and the virtual environment. Discussion focuses on how spatial-updating processes operate on perception and action and on representation and action.     

Major memory for microblogs

Online social networking is vastly popular and permits its members to post their thoughts as microblogs, an opportunity that people exploit, on Facebook alone, over 30 million times an hour. Such trivial ephemera, one might think, should vanish quickly from memory; conversely, they may comprise the sort of information that our memories are tuned to recognize, if that which we readily generate, we also readily store. In the first two experiments, participants’ memory for Facebook posts was found to be strikingly stronger than their memory for human faces or sentences from books—a magnitude comparable to the difference in memory strength between amnesics and healthy controls. The second experiment suggested that this difference is not due to Facebook posts spontaneously generating social elaboration, because memory for posts is enhanced as much by adding social elaboration as is memory for book sentences. Our final experiment, using headlines, sentences, and reader comments from articles, suggested that the remarkable memory for microblogs is also not due to their completeness or simply their topic, but may be a more general phenomenon of their being the largely spontaneous and natural emanations of the human mind.     

Speaking two languages with different number naming systems: What implications for magnitude judgments in bilinguals at different stages of language acquisition?

Differences between languages in terms of number naming systems may lead to performance differences in number processing. The current study focused on differences concerning the order of decades and units in two-digit number words (i.e., unit-decade order in German but decade-unit order in French) and how they affect number magnitude judgments. Participants performed basic numerical tasks, namely two-digit number magnitude judgments, and we used the compatibility effect (Nuerk et al. in Cognition 82(1):B25–B33, 2001) as a hallmark of language influence on numbers. In the first part we aimed to understand the influence of language on compatibility effects in adults coming from German or French monolingual and German–French bilingual groups (Experiment 1). The second part examined how this language influence develops at different stages of language acquisition in individuals with increasing bilingual proficiency (Experiment 2). Language systematically influenced magnitude judgments such that: (a) The spoken language(s) modulated magnitude judgments presented as Arabic digits, and (b) bilinguals’ progressive language mastery impacted magnitude judgments presented as number words. Taken together, the current results suggest that the order of decades and units in verbal numbers may qualitatively influence magnitude judgments in bilinguals and monolinguals, providing new insights into how number processing can be influenced by language(s).     

Borderline personality disorder features predict negative outcomes 2 years later

In a sample of 351 young adults, the authors assessed whether borderline personality disorder (BPD) features prospectively predicted negative outcomes (poorer academic achievement and social maladjustment) over the subsequent 2 years, over and above gender and both Axis I and Axis II psychopathology. Borderline traits were significantly related to these outcomes, with impulsivity and affective instability the most highly associated. The present findings suggest that the impulsivity and affective instability associated with BPD leads to impairment in relating well with others, in meeting social role obligations, and in academic or occupational achievement. Therefore, these may be especially important features to target in interventions for BPD.     

Phonetic-semantic mediated false recognition: does activation fail to spread?

Spoken word recognition involves brief activation of candidate words. Six experiments examined whether words semantically related to phonologically activated words would be falsely recognized. Experiments 1 and 2 involved homophones as test words; Experiment 3 used strong associates for the semantic mediation link. Experiment 4 approximated lists of "strong" converging associates. Experiment 5 expanded the real time needed for word identification by using a gating procedure during study. In Experiment 6, the goal was to create a more sensitive test by requiring participants to indicate which of two lures (mediated or control) was "most likely" to be new. Recognition errors were sensitive to separate phonetic and semantic stages in the mediated chain; however, there was little evidence of mediated false recognition, despite expectations derived from common models of spreading activation.     

Interaction of emotion and cognition in word recall

Summary Previous research has demonstrated that the emotional properties of words and their imaginability affect their recallability and that verbal material is recalled better when it is related to subjects' current concerns. This study investigates the extent to which this effect of emotion on recall varies as a function of cognitively controllable inference processes and examines the relation of the effects of emotion to those of imaginability and concern-relatedness. Forty different words were presented visually under one of six orienting conditions that varied according to what the subject was asked to rate: their length, pronounceability, concreteness, defineability, the strength of emotion elicited by the word, and the relation of the word to personal concerns. Subjects were then asked to write as many words as they could recall. Words that aroused stronger emotion and were easier to represent in imagery were recalled better than emotionally less arousing and imaginally less evocative words, regardless of the nature of the orienting task. The evidence suggests that the emotional properties of words are evaluated automatically in an early processing stage, without requiring subjects to reflect on word content. Emotional arousal appears to mediate the effects of current concerns on recall. It is correlated with but appears to function independently of word imaginability.     

Workaholism,sex, and sex role stereotyping among female professionals

This paper examines the relationship between workaholism, sex, and sex role orientation among professionals. The sample consisted of 86 male and 106 female attorneys, physicians, and psychologists/therapists. Results indicated a significant relationship between sex and sex role stereotyping. Among females, workaholics were grouped exclusively in the sex role categories masculine and androgynous. Implications for counseling include increasing awareness of changing sex role attitudes among professional women and possible role conflict that can occur from integration of work and family.     

Physical characteristics of residential psychiatric and substance abuse programs: Organizational determinants and patient outcomes

Described the Physical and Architectural Characteristics Inventory (PACI), which assesses the physical characteristics of hospital- and community-based psychiatric and substance abuse residential treatment programs for adults. Developed using data from 94 representative programs, the PACI has 7 dimensions that assess community accessibility, physical features that add convenience, aid recreation, and provide support for patients, and space for patient and staff functions. In comparison to community-based programs (n=63), hospital programs (n=31) had more social-recreational and prosthetic aids, safety features, staff facilities, and space. The PACI dimensions were also related to other organizational features, such as facility ownership and program size and staffing level. Programs with more physical amenities had patients who were more involved in self-initiated and community activities and were more likely to successfully complete the program and be discharged to independent living situations and paid jobs. Programs with more social-recreational and prosthetic aids, space, and access to community resources also had better patient outcomes. In addition, PACI dimensions were related to observers' ratings of facility attractiveness. Potential applications of the PACI and the full inventory of which it is a part are discussed.     

Children's strategies in producing three-dimensional relationships on a two-dimensional surface

It is a common task to give children a picture containing implicit depth cues and to require them to extract depth information from it. The cues are always selected from the adult repertoire; little is known about children's production of their own cues. In this experiment, 5- to 10-year-old children were required to draw one object behind another in a situation in which adults invariably produce the further object partially occluded by the nearer. The results were an age-related decline in the tendency to segregate the objects and an increase in the tendency to group the objects using partial occlusion, with a cross-over at 8 years. At all ages some children drew one object inside the boundary of the other. It is argued that the results are composed of two tendencies, a gradual mastery of discrete scaling phenomena (e.g., “up” on the page means “further”) within a given style, and a set of decisions to be made between incompatible styles.