Experiences and Decisions that Motivate Women at Increased Risk of Breast Cancer to Participate in an Experimental Screening Program

Although the discovery of mutations on BRCA1 and BRCA2 genes associated with high breast cancer risk has given rise to screening and surveillance initiatives, there is little documentation on why high-risk women choose to enter screening programs. The objective of this qualitative study was to develop a detailed understanding of the experiences and decisions that motivate women with increased risk of hereditary breast cancer to participate in the multicentered Quebec experimental breast screening program. Our study involved 21 participants who were either BRCA carriers or at risk and untested. These women were interviewed while participating in the screening program. Our study demonstrates that intensive screening programs may provide valuable reassurance for women with increased familial risk of hereditary breast cancer, who count on early detection and rapid response from professionals if and when a problem arises. Health professionals must take these and others concerns into account to ensure their interventions are most consistent with women’s needs.     

Genetic Library: Grief and Bereavement

As genetic counselors, we frequently encounter families that have experienced a significant loss, be it a pregnancy, a child, or a parent. The purpose of this Genetic Library is to introduce genetic counselors to some of the research that is currently being conducted in the areas of grief and bereavement support, as well as end-of-life care. Of course, it is impossible to capture the richness of these articles in one or two paragraphs. We therefore encourage interested genetic counselors to request and review the full version of these papers.     

Early-Onset Bipolar Spectrum Disorders: Diagnostic Issues

Since the mid 1990s, early-onset bipolar spectrum disorders (BPSDs) have received increased attention in both the popular press and scholarly press. Rates of diagnosis of BPSD in children and adolescents have increased in inpatient, outpatient, and primary care settings. BPSDs remain difficult to diagnose, particularly in youth. The current diagnostic system makes few modifications to accommodate children and adolescents. Researchers in this area have developed specific BPSD definitions that affect the generalizability of their findings to all youth with BPSD. Despite knowledge gains from the research, BPSDs are still difficult to diagnose because clinicians must: (1) consider the impact of the child’s developmental level on symptom presentation (e.g., normative behavior prevalence, environmental limitations on youth behavior, pubertal status, irritability, symptom duration); (2) weigh associated impairment and course of illness (e.g., neurocognitive functioning, failing to meet full DSM criteria, future impairment); and (3) make decisions about appropriate assessment (differentiating BPSD from medical illnesses, medications, drug use, or other psychiatric diagnoses that might better account for symptoms; comorbid disorders; informant characteristics and assessment measures to use). Research findings concerning these challenges and relevant recommendations are offered. Areas for further research to guide clinicians’ assessment of children with early-onset BPSD are highlighted. Principal Investigators and Coinvestigators of Longitudinal Assessment of Manic Symptoms (LAMS) Group are listed in Appendix.     

The shift in infant preferences for vowel duration and pitch contour between 6 and 10 months of age

This study investigates the influence of the acoustic properties of vowels on 6‐ and 10‐month‐old infants’ speech preferences. The shape of the contour (bell or monotonic) and the duration (normal or stretched) of vowels were manipulated in words containing the vowels /i/ and /u/, and presented to infants using a two‐choice preference procedure. Experiment 1 examined contour shape: infants heard either normal‐duration bell‐shaped and monotonic contours, or the same two contours with stretched duration. The results show that 6‐month‐olds preferred bell to monotonic contours, whereas 10‐month‐olds preferred monotonic to bell contours. In Experiment 2, infants heard either normal‐duration and stretched bell contours, or normal‐duration and stretched monotonic contours. As in Experiment 1, infants showed age‐specific preferences, with 6‐month‐olds preferring stretched vowels, and 10‐month‐olds preferring normal‐duration vowels. Infants’ attention to the acoustic qualities of vowels, and to speech in general, undergoes a dramatic transformation in the final months of the first year, a transformation that aligns with the emergence of other developmental milestones in speech perception.     

Measuring subjective well-being: A comparison of China and the USA

In this article the structure of subjective well-being (SWB), the relationship between household income and SWB and mean differences in components of SWB in China and the USA are investigated. Both China and the USA were characterized in a three-factor model of SWB (life satisfaction, positive affect and negative affect). Household income was more strongly positively correlated with the three major components of SWB in China than in the USA. Lower levels of SWB were generally reported by participants in China than in the USA; however, there were mean differences in different regions of China.     

Therapie des chronisch-komplexen Tinnitus

Tinnitus ist ein Ph?nomen, welches für fast jeden Menschen physiologisch unter ruhigen Umgebungsbedingungen subjektiv wahrnehmbar wird. Im psychosomatisch-psychotherapeutischen Setting ist dieses Symptom in der Regel im Rahmen einer Somatisierungsst?rung (F45.0; F45.1) oder des chronisch-komplexen Tinnitus (F54.0, H93.1) anzutreffen. In der vorliegenden Arbeit wird ein integrativer HNO-?rztlicher und psychosomatischer Therapieansatz vorgestellt: Ziel der Behandlung ist es, die Komponenten der akustischen Wahrnehmung zu reorganisieren, das Ohrger?usch und die psychisch emotionale Wertung zu entkoppeln sowie dessen psychologische Bedeutung zu ?ndern. Weiters wird ein Modell vorgestellt, wie die Depression – als h?ufigste komorbide Achse-I-St?rung – in das diagnostisch- therapeutische Erkl?rungsmodell integriert werden kann. Zuletzt werden M?glichkeiten er?rtert, wie Patienten mit chronisch-komplexem Tinnitus zur Aufnahme einer psychotherapeutischen Behandlung motiviert werden k?nnen.     

国外社会惰性的理论与相关研究概述

社会惰性是团队成员在从事趋向共同目标活动中出现的努力程度和平均贡献随着群体成员增加而减少的现象。该研究从社会惰性的概念、起源和发展、理论解释,影响因素及形成过程等几个方面对国外社会惰性的研究状况进行了述评,并指出存在的问题及今后研究的方向     

应激诱发复吸的动物模型及其神经生物学基础

复吸是药物成瘾的重要特征,应激是诱发复吸的因素之一。该文介绍了用于研究应激诱发复吸的动物恢复模型,阐述了涉及应激诱发复吸的神经生物学基础。大量研究结果表明,下丘脑外侧的终纹床核与杏仁核内的促肾上腺皮质激素释放因子和去甲肾上腺素是参与应激诱发复吸的重要神经递质。内侧前额叶皮层可能是介导应激、药物点燃及药物相关线索等各类因素诱发复吸的共同通路     

虚拟社会关系的心理学研究及展望

随着计算机及网络的普及,一种新型的、不同于传统“面对面（facetoface）”交往的社会关系——虚拟社会关系（virtualsocialrelationship）——已逐渐形成。该文从心理学角度对虚拟交往的动机、影响虚拟关系发展的因素及“虚拟”与“现实”的关系等进行了阐述,并在此基础上对未来虚拟社会关系的研究取向进行了展望,认为虚拟社会关系形成的心理基础、心理机制等将成为今后的研究热点     

组织伦理气氛的理论与研究

组织伦理气氛（organizationalethicclimate）是组织成员对组织伦理环境特性的一致性认知。在文献研究的基础上,该文首先从伦理与组织伦理、组织伦理气氛的概念来源与形成、结构与测量、影响因素及其与组织绩效的关系等方面,对国外组织伦理气氛研究进行了归纳和反思,并从理论研究与管理实践方面提出了一些具体的建议