Genetic Counseling Considerations in the Evaluation of Families for Lynch Syndrome��A Review

Lynch syndrome is the most common hereditary colorectal cancer syndrome and the most common cause of hereditary endometrial cancer. Identifying and evaluating families for Lynch syndrome is increasing in complexity due to the recognition that: family history-based clinical criteria lack sensitivity and specificity; genetic testing for Lynch syndrome continues to evolve as understanding of the molecular mechanisms underlying it evolves; and the Lynch syndrome phenotype encompasses multiple organ systems and demonstrates overlap with other hereditary cancer syndromes. This document is a summary of considerations when evaluating individuals and families for Lynch syndrome, including information on cancer risks, diagnostic criteria, tumor and genetic testing strategies, and the management of individuals with this condition.     

Association Between Independent Reports of Maternal Parenting Stress and Children’s Internalizing Symptomatology

Although considerable research has investigated parenting stress and children’s externalizing behavior problems, comparatively less has considered parenting stress in relation to children’s internalizing difficulties. Even less research on parenting stress has incorporated children’s report of their internalizing symptoms or the potential mediating role of children’s attributional style. The current study hypothesized that children’s independent reports of internalizing symptoms would be associated with mothers’ reports of parenting stress through children’s attributional style. A community sample of 92 mother–child dyads participated. Results suggest maternal parenting stress from both child and parent sources were significantly associated with children’s anxious and depressive symptoms. Parenting stress was associated with children’s internalizing symptoms partially mediated by children’s maladaptive attributional style, primarily negative attributions for positive outcomes. Findings are discussed in terms of future directions to tease apart specific areas of parenting stress that may be most pertinent as well as to explore other cognitive mechanisms in children that may relate to parenting stress and children’s adjustment.     

Psychometric properties of the Miranda Rights Comprehension Instruments with a juvenile justice sample

This article describes the psychometric properties of the Miranda Rights Comprehension Instruments, the revised version of Grisso's Miranda instruments. The original instruments demonstrated good reliability and validity in a normative sample. The revised instruments updated the content of the original instruments and were administered to a sample of 183 youth in pre- and postadjudication facilities. Analyses were conducted to establish the psychometric properties of the revised instruments and included similar analyses to those conducted by Grisso, as well as additional calculations (e.g., standard errors of measurement, intraclass correlation coefficients, Kappa coefficients). Results revealed sound psychometric properties, similar to those observed for the original instruments.     

Ethics in 15 min per Week

The demand for science trainees to have appropriate responsible conduct of research instruction continues to increase the attention shown by federal agencies and graduate school programs to the development of effective ethics curriculums. However, it is important to consider that the main learning environment for science graduate students and post-doctoral research fellows is within a laboratory setting. Here we discuss an internal laboratory program of weekly 15-minute ethics discussions implemented and used over the last 3 years in addition to the graduate school’s program of scientific integrity training. During this time, the environment and culture within our laboratory has changed to place greater emphasis on the ethical implications of our own research and the research we evaluate. We still struggle with how to accurately assess this behavioral change; although, we present preliminary survey results on the evaluation and impact of this style of curriculum for ethics instruction in our laboratory.     

Impact of Remembering Childhood Sexual Abuse on Addiction Recovery for Young Adult Lesbians

This article examines the impact of childhood sexual abuse on young adult lesbians' sexual identity and their recovery from chemical dependency. The authors recommend that counselors assess for sexual orientation (past and present), sexual abuse, and possible dual diagnosis. Implications for counselors are discussed.     

Implicit causality bias in English: a corpus of 300 verbs

This study provides implicit verb causality norms for a corpus of 305 English verbs. A web-based sentence completion study was conducted, with 96 respondents completing fragments such as “John liked Mary because...” The resulting bias scores are provided as supplementary material in the Psychonomic Society Archive, where we also present lexical and semantic verb features, such as the frequency, semantic class and emotional valence. Our results replicate those of previous studies with much smaller numbers of verbs and respondents. Novel effects of gender and its interaction with verb valence illustrate the type of issues that can be investigated using stable norms for a large number of verbs. The corpus will facilitate future studies in a range of areas, including psycholinguistics and social psychology.     

Intracerebral source generators characterizing concentrative meditation

Previous researchers have studied meditation practices as a means to understand consciousness as well as altered states of consciousness. Various meditation techniques, such as Transcendental Meditation (TM) and Qigong, have been explored with source localization tools; however, the concentrative meditation technique has yet to be fully studied in this manner. The current study demonstrates findings, which outline differential activation in a self-referential default network during meditation in participants who espouse themselves as regular concentrative meditation practitioners, as well as comparisons with a control group practicing a modified version of the relaxation response. The results are compared with other putative experimental findings employing other meditation techniques, and the findings outlined in the current study are discussed with respect to changes in perceptual awareness often reported by meditators.     

Influences on employee perceptions of organizational work–life support: Signals and resources

This study examined predictors of employee perceptions of organizational work–life support. Using organizational support theory and conservation of resources theory, we reasoned that workplace demands and resources shape employees' perceptions of work–life support through two mechanisms: signaling that the organization cares about their work–life balance and helping them develop and conserve resources needed to meet work and nonwork responsibilities. Consistent with our hypotheses, we found that higher demands (work hours and work overload) were associated with reduced perceptions that the organization was supportive of work–life integration. Resources (job security, fit between employees' needs and the flexible work options available to them, supervisor support and work group support) were positively associated with perceptions of organizational work–life support. The results of this study urge further scholarly attention to work-based demands and resources as predictors of perceived organizational work–life support and yield implications for managerial practice.     

A test of written emotional disclosure as an intervention for posttraumatic stress disorder

This study examined the efficacy of the written emotional disclosure (WED) procedure with a sample of young adults who met diagnostic criteria for posttraumatic stress disorder (PTSD). Participants were randomly assigned to either WED or a control writing condition and were assessed at baseline and one month following the writing sessions. During each writing session, participants’ heart rate was recorded; participants also provided self-report ratings of emotional responding. Findings indicated no significant group differences for PTSD and depression symptom severity at follow-up assessment. Relative to control participants, WED participants displayed significantly greater heart rate activity and reported greater emotional responding during the first writing session; however, no reduction in emotional responding occurred for either condition from the first to the last writing session. Taken together, these findings indicate that WED may not be an efficacious intervention for PTSD. Suggestions are made for future work in this area.     

The ABCs of CBT (Cognitive Behavior Therapy): Evidence‐Based Approaches to Child Anxiety in Public School Settings

This study evaluated a locally developed cognitive behavior therapy (CBT) intervention program in a public elementary school. In the prevention approach, 118 children were randomly assigned either to an 8‐week intervention or to a waitlist control. Results of statistical analysis indicated that the manualized CBT intervention did not reduce symptoms of anxiety on either self‐reports or parent reports of anxiety symptoms in the general school population. Challenges to translational efforts to public school settings are discussed.