Mental fatigue influence on effort-related cardiovascular response: difficulty effects and extension across cognitive performance domains

Two experiments investigated cardiovascular effects of mental fatigue as a function of (1) the difficulty of the cognitive challenge with which participants were confronted, and (2) the relevance of that challenge to the activity that instigated the fatigue. In the first, participants performed an easy (fatigue low) or difficult (fatigue high) counting task and then were presented an arithmetic challenge (task B relevance high) or a scanning challenge (task B relevance low) with instructions that they would avoid a noise if they attained a modest performance standard. Analysis of blood pressure responses assessed during the work periods revealed fatigue main effects, reflecting stronger responses for High Fatigue participants, regardless of the character of the second task. In the second, the procedure was the same except that it included a high performance standard and provided the chance to win a prize. Analysis of the pressure data revealed fatigue x work period interactions, reflecting relatively stronger responses among High Fatigue participants in work period 1, but relatively weaker responses among these participants in work period 2. Results confirm previous findings and support an analysis of fatigue influence on effort and associated cardiovascular responses. They also argue against the idea that mental fatigue influence may be confined to relevant cognitive performance realms.

Testing the Model of Influence of Presumed Influence in a Boundary Condition: The Impact of Question Order

We argue that evidence for and utility of the Influence of Presumed Influence (IPI) model lies in a robust causal chain in the form of self‐exposure → other‐exposure → perceived effects on others → behavior. A review of extant literature reveals competing theoretical explanations, as well as the possibility that a method factor (question order) could have driven the obtained models in structural equation modeling (SEM) analyses. The IPI model was tested in the boundary condition of different question orders using data from a web‐based experimental study. The results from 2‐group model SEM analyses show that the causal directions among presumed influence and media effects schema variables are indeed a function of question order.     

A Review of “Suicidal Intent” Within the Existing Suicide Literature

The results of a systematic literature review that investigated suicide intent are presented. Of the 44 relevant articles identified, 17 investigated the relationships between various suicide risk factors and suicide intent and 25 publications investigated the relationships between suicide intent and various suicide outcomes. Despite recent advancements in the definition and nomological validity of suicide intent, a high degree of variability in the empirical measurement and analysis of suicide intent was found. Such variability limits future research related to measuring suicidal risk and outcomes, reporting suicide intent, or the meaningful comparison of diagnostic approaches or treatments across multiple studies.     

Normal Functioning and the Treatment/Enhancement Distinction: An Opportunity Based Assessment

As genome mapping technology uncovers the roots of pathologic and physiologic human functioning, important questions are brought to the fore concerning our conceptualization of ideas such as disease, treatment, and enhancement. In 1985, Norman Daniels proposed a normal-functioning model that expands John Rawls’ theory of justice to obligate the provision of health care based on the constraints disease places on individual opportunity, but also limits the commitment of the medical establishment by focusing on states that represent deviations from normal human function. While some argue that the boundaries of medical institutions’ commitment to provide services within a normal-functioning model are arbitrary, the degree to which these concerns truly threaten the framework is often exaggerated in special cases put forward in the literature. Furthermore, the normal-functioning model provides a comprehensive basis for agreement in discussions of medicine’s commitment to the demands of social justice where resources are limited and avoids the dangerous overextension of the healthcare system and medicalization to which more expansive models are exposed.     

Antecedents of Business Opportunity Identification and Innovation: Investigating the Interplay of Information Processing and Information Acquisition

Building on conceptual frameworks of entrepreneurial discovery, we argue that active information search compensates for a lack of entrepreneurial experience and enhances the effects of divergent thinking and general mental ability (GMA) on opportunity identification. We sampled 100 business owners in South Africa. Results confirmed the hypothesised moderating effects of active information search on the relationships of entrepreneurial experience and divergent thinking on opportunity identification. Furthermore, we found direct effects of opportunity identification and conditional indirect effects of divergent thinking on innovativeness of product/service innovations. Our findings suggest that a joint examination of entrepreneurial experience and divergent thinking with active information search helps to better understand opportunity identification.     

Coping style and memory specificity in adolescents and adults with histories of child sexual abuse

Individuals with histories of childhood trauma may adopt a nonspecific memory retrieval strategy to avoid unpleasant and intrusive memories. In a sample of 93 adolescents and adults with or without histories of child sexual abuse (CSA), we tested the hypothesis that nonspecific memory retrieval is related to an individual's general tendency to use avoidant (i.e., distancing) coping as a personal problem-solving or coping strategy, especially in victims of CSA. We also examined age differences and other individual differences (e.g., trauma-related psychopathology) as predictors of nonspecific memories. Distancing coping was significantly associated with less specific autobiographical memory. Younger age, lower vocabulary scores, and non-CSA childhood maltreatment (i.e., physical and emotional abuse) also uniquely predicted less autobiographical memory specificity, whereas trauma-related psychopathology was associated with more specific memory. Implications for the development of autobiographical memory retrieval in the context of coping with childhood maltreatment are discussed.     

Minimal Risk of Internalizing Problems in Typically-Developing Siblings of Children with High-Functioning Autism Spectrum Disorder

We examined anxiety and depression clinical symptom levels in 42 typically-developing (TD) siblings of children with high-functioning autism spectrum disorder (HFASD), compared to 42 TD siblings of TD children, matched on age, ethnicity, and gender. Participants were between the ages of 6 and 16. Groups were compared using the parent-report and child self-report versions of the Behavior Assessment System for Children, Second Edition, anxiety and depression clinical scales. Within-group differences were examined for parent versus child ratings. Multivariate procedures did not support clinically elevated levels of internalizing problems in siblings of children with HFASD. Results from both sources were consistent with the overall finding. The findings do not support an increased need for targeted intervention, though clinical and school-based practitioners should attend to clinical warning signs if presented.     

Return of Genetic Results in the Familial Dilated Cardiomyopathy Research Project

The goal of the Familial Dilated Cardiomyopathy (FDC) Research Project, initiated in 1993, has been to identify and characterize FDC genetic cause. All participating individuals have been consented for the return of genetic results, an important but challenging undertaking. Since the inception of the Project we have enrolled 606 probands, and 269 of these had 1670 family members also enrolled. Each subject was evaluated for idiopathic dilated cardiomyopathy (IDC) and pedigrees were categorized as familial or sporadic. The coding regions of 14 genes were resequenced in 311 to 324 probands in five studies. Ninety-two probands were found to carry nonsynonymous rare variants absent in controls, and with Clinical Laboratory Improvement Amendment of 1988 (CLIA) compliant protocols, relevant genetic results were returned to these probands and their consented relatives by study genetic counselors and physicians in 353 letters. In 10 of the 51 families that received results >1 year ago, at least 23 individuals underwent CLIA confirmation testing for their family’s rare variant. Return of genetic results has been successfully undertaken in the FDC Research Project. This report describes the methods utilized in the process of returning research results. We use this information as a springboard for providing guidance to other genetic research groups and proposing future directions in this arena.     

Teenagers,contraception, and pregnancy

The Hospital of the University of Pennsylvania started a family planning counseling program for teenage nulliparae in a nearby public high school in 1973-1974. Educational, informal counseling, and discussion sessions were held in the school on a weekly basis by a social worker, family planning nurse, family planning counselor, and male outreach worker. Following the classes, almost half the girls attended the hospital's Teen Clinic for physical examination and contraceptive supplies. Parental permission was not necessary for attendance at the classes or at the hospital clinic. A second program was started at another school in the year 1974-1975. The goal of the program was to offer family planning information in the early teen years and prevent unwanted pregnancy.     

Pain anxiety, acceptance, and outcomes among individuals with HIV and chronic pain: a preliminary investigation

The current study investigated the role of during treatment changes in pain anxiety in the relation between during treatment changes in pain acceptance and chronic pain outcomes. Participants included 45 (15 women) adults (M_age = 50.42, SD = 7.69) who were HIV positive and experienced chronic pain. They were offered 12 weekly, 90-min group CBT sessions to increase understanding about chronic pain and to improve coping skills. Four hierarchical regression analyses were conducted to examine the mediating role of treatment changes in pain anxiety in the relation between treatment changes in pain acceptance and chronic pain outcomes. Results suggest that increases in pain acceptance during treatment were associated with decreased levels of pain anxiety during treatment, as well as decreases in pain-related impairment at treatment completion. Furthermore, decreases in pain anxiety during treatment were associated with decreases in pain-related impairment at treatment completion. Finally, treatment changes in pain anxiety were found to partially mediate the association between treatment changes in pain acceptance and pain-related impairment at treatment completion. Results are discussed within the context of better understanding the processes of change within a CBT model for chronic pain patients.