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311.
Long-term synaptic plasticity exhibits distinct phases. The synaptic tagging hypothesis suggests an early phase in which synapses are prepared, or "tagged," for protein capture, and a late phase in which those proteins are integrated into the synapses to achieve memory consolidation. The synapse specificity of the tags is consistent with conventional neural network models of associative memory. Memory consolidation through protein synthesis, however, is neuron specific, and its functional role in those models has not been assessed. Here, using a theoretical network model, we test the tagging hypothesis on its potential to prolong memory lifetimes in an online-learning paradigm. We find that protein synthesis, though not synapse specific, prolongs memory lifetimes if it is used to evaluate memory items on a cellular level. In our model we assume that only "important" memory items evoke protein synthesis such that these become more stable than "unimportant" items, which do not evoke protein synthesis. The network model comprises an equilibrium distribution of synaptic states that is very susceptible to the storage of new items: Most synapses are in a state in which they are plastic and can be changed easily, whereas only those synapses that are essential for the retrieval of the important memory items are in the stable late phase. The model can solve the distal reward problem, where the initial exposure of a memory item and its evaluation are temporally separated. Synaptic tagging hence provides a viable mechanism to consolidate and evaluate memories on a synaptic basis. 相似文献
312.
Wine, in France, is a cultural product. However, the issue of wine consumption has been at the centre of a recurring social debate. We decided to focus our study on the effect of consumption practices on this social representation as well as the variations in position-taking in very different normative contexts. Results revealed two distinct social representations according to consumption practice. Moreover, Guttman effect in principal component analysis uncovered a unique phenomenon which showed that participants (consumer vs. non consumer) were inclined to act differently only in the case of polemical issues when they perceived the investigator as a consumer vs. non consumer. Indeed, in the case of hegemonic beliefs they were inclined to act in the same way and their answers were not influenced by the status of the investigator. Results are discussed around the question of the links between social representations and social identity. 相似文献
313.
Markett S Montag C Walter NT Plieger T Reuter M 《Cognitive, affective & behavioral neuroscience》2011,11(4):644-651
The adjustment of behavior to changing goals and environmental constraints requires the flexible switching between different
task sets. Cognitive flexibility is an endophenotype of executive functioning and is highly heritable, as indicated by twin
studies. Individual differences in global flexibility as assessed by reaction-time measurement in a task-switching paradigm
were recently related to a single nucleotide polymorphism in the vicinity of the dopamine d2 receptor gene DRD2. In the present
study, we assessed whether the DRD2 gene is related to backward inhibition, a control mechanism that contributes to cognitive
flexibility by reducing proactive interference by no longer relevant task sets. We found that carriers of the DRD2 A1+ variant
who have a lower striatal dopamine d2 receptor density than A1– carriers show a larger backward inhibition effect. This is
in line with previous results demonstrating increased behavioral flexibility in carriers of this genetic variant. The discussion
relates the present finding to those of previous studies assessing the neurogenetic foundations of inhibitory control. 相似文献
314.
Berman MG Nee DE Casement M Kim HS Deldin P Kross E Gonzalez R Demiralp E Gotlib IH Hamilton P Joormann J Waugh C Jonides J 《Cognitive, affective & behavioral neuroscience》2011,11(1):85-96
Individuals diagnosed with major depressive disorder (MDD) often ruminate about their depression and their life situations, impairing their concentration and performance on daily tasks. We examined whether rumination might be due to a deficit in the ability to expel negative information from short-term memory (STM), and fMRI was used to examine the neural structures involved in this ability. MDD and healthy control (HC) participants were tested using a directed-forgetting procedure in a short-term item recognition task. As predicted, MDD participants had more difficulty than did HCs in expelling negative, but not positive, words from STM. Overall, the neural networks involved in directed forgetting were similar for both groups, but the MDDs exhibited more spatial variability in activation in the left inferior frontal gyrus (a region critical for inhibiting irrelevant information), which may contribute to their relative inability to inhibit negative information. 相似文献
315.
Field studies and laboratory experiments have documented that a key component of resilience is emotional flexibility--the ability to respond flexibly to changing emotional circumstances. In the present study we tested the hypotheses that resilient people exhibit emotional flexibility: (a) in response to frequently changing emotional stimuli and (b) across multiple modalities of emotional responding. As participants viewed a series of emotional pictures, we assessed their self-reported affect, facial muscle activity, and startle reflexes. Higher trait resilience predicted more divergent affective and facial responses (corrugator and zygomatic) to positive versus negative pictures. Thus, compared with their low-resilient counterparts, resilient people appear to be able to more flexibly match their emotional responses to the frequently changing emotional stimuli. Moreover, whereas high-trait-resilient participants exhibited divergent startle responses to positive versus negative pictures regardless of the valence of the preceding trial, low-trait-resilient participants did not exhibit divergent startle responses when the preceding picture was negative. High-trait-resilient individuals, therefore, appear to be better able than are their low-resilient counterparts to either switch or maintain their emotional responses depending on whether the emotional context changes. The present findings broaden our understanding of the mechanisms underlying resilience by demonstrating that resilient people are able to flexibly change their affective and physiological responses to match the demands of frequently changing environmental circumstances. 相似文献
316.
Visual co-orientation with another's gaze direction (gaze following) may provide important information about the location of food, social interactions or predators. Gaze following has been shown in a variety of mammals, but only in few bird species, and has not been tested in precocial birds at all. It has been suggested that gaze following is an anti-predator behaviour, and in Common ravens (Corvus corax) and rooks (C. frugilegus), it emerges shortly after fledging, at a time when young birds leave the predator-safe nest. However, if gaze following is adaptive, the developmental pattern should differ between altricial and precocial birds. Greylag geese (Anser anser) are highly social birds with a precocial development. Goslings move and feed independently within 24 h post-hatching, and they are highly vulnerable to aerial predators. We therefore predicted that greylag geese are capable of gaze following and that they develop this skill already pre-fledging. We experimentally tested 19 hand-raised greylag goslings for their ability to follow a conspecific's gaze when they were between 10 days and 6 weeks old. In line with our predictions, first responses were already detectable in 10-day-old goslings. Our results therefore not only demonstrate that greylag geese follow the gaze of conspecifics into distant space, but that they also develop this ability much earlier than altricial birds. 相似文献
317.
Smith TS Isaak MI Senette CG Abadie BG 《Cyberpsychology, behavior and social networking》2011,14(6):351-358
This study examined the effects of electronic communication distractions, including cell-phone and texting demands, on true and false recognition, specifically semantically related words presented and not presented on a computer screen. Participants were presented with 24 Deese-Roediger-McDermott (DRM) lists while manipulating the concurrent presence or absence of cell-phone and text-message distractions during study. In the DRM paradigm, participants study lists of semantically related words (e.g., mother, crib, and diaper) linked to a non-presented critical lure (e.g., baby). After studying the lists of words, participants are then requested to recall or recognize previously presented words. Participants often not only demonstrate high remembrance for presented words (true memory: crib), but also recollection for non-presented words (false memory: baby). In the present study, true memory was highest when participants were not presented with any distraction tasks during study of DRM words, but poorer when they were required to complete a cell-phone conversation or text-message task during study. False recognition measures did not statistically vary across distraction conditions. Signal detection analyses showed that participants better discriminated true targets (list items presented during study) from true target controls (items presented during study only) when cell-phone or text-message distractions were absent than when they were present. Response bias did not vary significantly across distraction conditions, as there were no differences in the likelihood that a participant would claim an item as "old" (previously presented) rather than "new" (not previously presented). Results of this study are examined with respect to both activation monitoring and fuzzy trace theories. 相似文献
318.
Jens Bölte Andrea Böhl Christian Dobel Pienie Zwitserlood 《Journal of Cognitive Psychology》2013,25(8):1166-1199
In five experiments, participants were asked to describe unambiguously a target picture in a picture–picture paradigm. In the same-category condition, target (e.g., water bucket) and distractor picture (e.g., ice bucket) had identical names when their preferred, morphologically simple, name was used (e.g., bucket). The ensuing lexical ambiguity could be resolved by compound use (e.g., water bucket). Simple names sufficed as means of specification in other conditions, with distractors identical to the target, completely unrelated, or geometric figures. With standard timing parameters, participants produced mainly ambiguous answers in Experiment 1. An increase in available processing time hardly improved unambiguous responding (Experiment 2). A referential communication instruction (Experiment 3) increased the number of compound responses considerably, but morphologically simple answers still prevailed. Unambiguous responses outweighed ambiguous ones in Experiment 4, when timing parameters were further relaxed. Finally, the requirement to name both objects resulted in a nearly perfect ambiguity resolution (Experiment 5). Together, the results showed that speakers overcome lexical ambiguity only when time permits, when an addressee perspective is given and, most importantly, when their own speech overtly signals the ambiguity. 相似文献
319.
Unkelbach C 《Psychological science》2006,17(4):339-345
The fluency of cognitive processes influences many judgments: Fluently processed statements are judged to be true, fluently processed instances are judged to be frequent, and fluently processed names are judged to be famous. According to a cue-learning approach, these effects of experienced fluency arise because the fluency cue is interpreted differentially in accordance with its learned validity. Two experiments tested this account by manipulating the fluency cue's validity. Fluency was manipulated by color contrast (Experiment 1) and by required mental rotation (Experiment 2). If low fluency was correlated with a required affirmative or "old" response (and high fluency with a negative or "new" response) in a training phase, participants showed a reversal of the classic pattern in the recognition phase: Low-fluency stimuli had a higher probability than high-fluency stimuli to be classified as old. Thus, the interpretation and therefore the impact of fluency depended on the cue's learned validity. 相似文献
320.
Ray WJ Odenwald M Neuner F Schauer M Ruf M Wienbruch C Rockstroh B Elbert T 《Psychological science》2006,17(10):825-829
From a neuroscience perspective, little is known about the long-term effect of torture. Dissociative experiences and posttraumatic stress disorder are often the results of this experience. We examined psychological dissociation within a group of 23 torture victims and report its manifestations within neural networks in the human brain. In particular, we observed that dissociative experiences are associated with slow abnormal brain waves generated in left ventrolateral frontal cortex. Given that focal slow waves often result from depriving neural networks of major input, the present results may indicate decoupling of frontal affective processors from left cortical language areas. This interpretation is consistent with the fact that disturbed access to structured verbal memory concerning traumatic events is a core feature of the dissociative experience. 相似文献