The 10th Oxbridge varsity medical ethics debate-should we fear the rise of direct-to-consumer genetic testing?

In an increasingly data-driven age of medicine, do companies that offer genetic testing directly to patients represent an important part of personalising care, or a dangerous threat to privacy? Should we celebrate this new mechanism of patient involvement, or fear its implications?The Universities of Oxford and Cambridge addressed these issues in the 10th annual Medical Ethics Varsity Debate, through the motion: “This House Regrets the Rise of Direct-to-Consumer Genetic Testing”. This article summarises and extends key arguments made in the debate, exploring the impacts of such genetic testing on both the individual patient and broader society, with special consideration as to whether companies can ever truly guarantee anonymity of genetic data.     

The Moderating Roles of Perceived Task Interdependence and Team Size in Transformational Leadership’s Relation to Team Identification: A Dimensional Analysis

This study is aimed at investigating perceived task interdependence and team size as contingencies for team leaders’ transformational leadership influence on team identification. Data were obtained from a two-phase survey among 234 employees from ten multinational pharmaceutical subsidiaries in South Korea. Each dimension of transformational leadership by team leaders relates positively to team identification. However, the impact of leadership dimensions on team identification is attenuated by distinct moderator(s): charisma by higher perceived task interdependence, individualized consideration by larger team size, and intellectual stimulation by higher perceived task interdependence or larger team size. This study’s findings help us develop a more nuanced understanding of how transformational leadership operates. This study illustrates that team leaders’ transformational influence on team identification fluctuates, depending on the team structure. Such knowledge may help inform team leader development and team-structuring strategies used by practitioners and may contribute to improving organizational team effectiveness. This is one of the first studies showing evidence that the influence of the dimensions of transformational leadership is contingent upon distinct moderators, thereby contributing to advancing the theory of transformational leadership. Further, this study, by investigating team structure as a contingency of the transformational leadership-team identification relationship, complements previous research that focused on follower characteristics. Additionally, our explicit attention to the team as both the context of leaders’ action and the target of employee identification helps us gain a more concrete understanding of team leadership and team development issues, which are particularly salient in the highly competitive pharmaceutical industry.     

Six-year-olds' perception of home literacy environment and its influence on children's literacy enjoyment,frequency, and early literacy skills

Home literacy environment (HLE) makes an important contribution to children's reading acquisition in early years. Even though some research on children's perception exists, children's reports about HLE have been neglected. The present study focuses on N = 281 six-year-old's reports about HLE and its influences on literacy enjoyment, frequency, and early literacy skills. Parents' educational background was expected to predict children-perceived HLE. A positive impact of active HLE on literacy enjoyment and frequency were found. HLE also mediates the relation between parents' background and enjoyment. The importance of children's perspective on HLE regarding family literacy programs is discussed.     

Vernacularizing Jñāndev: Hagiography and the Process of Vernacularization

The process of vernacularization involves more than literary language, but also invokes social ethics and an investment in the idioms of everyday life. Vernacularization can reach beyond texts to enact its force upon biographies as well, altering the ethics and quotidian memory of sacred figures. The paper examines how texts and biographical memory identified with the medieval Marathi “saint” (sant) Jñāndev (about thirteenth century) underwent a process of vernacularization that altered the social ethics of texts associated with Jñāndev and with the public memory of the saint himself. In particular, issues of caste and gender as subjects of the process of vernacularization are discussed, and especially in the context of producing bhakti publics—social spheres of devotion—that merge with the Vārkarī religious tradition in Maharashtra.     

Creative Thinking in an Emotional Context: Specific Relevance of Executive Control of Emotion-Laden Representations in the Inventiveness in Generating Alternative Appraisals of Negative Events

Although divergent thinking ability in different domains may largely rely on the same basic executive functions, domain-specific functions may also be important, in particular when it comes to more real-life creativity demands. This study investigated if functional executive control of emotion-laden representations may be specifically relevant in cognitive reappraisal, which implies being creative in an affective context. In a sample of 88 healthy individuals, the relation between the participants’ inventiveness in generating positive reappraisals of adverse events (Reappraisal Inventiveness Test) and in generating novel ideas without emotional component (conventional divergent thinking test) to their executive functioning in tasks without (Mittenecker Pointing Test) and with emotional contribution (humor processing task) was studied. In line with hybrid models of creative thinking, poorer basic inhibition skills were found to be associated with poorer fluency performance in both divergent thinking tasks. Relations applied more specifically to reappraisal inventiveness when it came to executive processes with a more prominent emotional component. Creative performance in both tasks may have been hampered by time limits. The results support the notion that, in addition to basic executive functioning, more specific cognitive control functions are implicated in more real-life creative performance, according to related domain-specific demands.     

The Best Possible Selves Intervention: A Review of the Literature to Evaluate Efficacy and Guide Future Research

Since its inception in 2001, the best possible selves (BPS) activity has been the focus of more than 30 studies which have shown it to be a viable intervention for increasing optimism, positive affect, health and well-being. It is timely to critically review the findings from the BPS literature and suggest directions for future research. The majority of BPS studies have used an experimental methodology and have administered the BPS activity to diverse groups including students, adults, depressive individuals and suicidal inpatients. The BPS intervention can be effective when administered in-person or on-line and repeating the activity appears to enhance efficacy. Suggestions for future research include: (a) investigation of mediator variables, (b) additional outcome variables such as hope and appreciation, (c) comparative studies regarding dosage to enhance effectiveness, (d) extension of the BPS into a best-possible-other activity, (e) diversity of delivery methods, and (f) thematic content analysis of BPS text.     

A New Look at Celebrity Endorsements in Politics: Investigating the Impact of Scandalous Celebrity Endorsers and Politicians’ Best Responses

When a celebrity receives negative news coverage, his or her endorsements of politicians can pose negative consequences for the politicians. We investigated such negative consequences with the help of two experimental studies. In Study 1 (celebrity involved in tax scandal), we manipulated whether an endorsement was initiated by a politician or a celebrity (i.e., controllability) in a 2 × 2 between-subject experiment. We also manipulated politicians’ responses (i.e., no response vs. response). Study 2 was a conceptual replication of the first experiment (celebrity involved in a real estate scandal). Results of Study 1 revealed that politicians are perceived to be more in control of self-initiated endorsements than other-initiated ones. Perceived controllability, in turn, influenced feelings of anger and pity, eventually affecting voting intentions. For self-initiated endorsements, no response appears to be the best reaction. By contrast, public response is advised when the endorsement was initiated by another entity. Results were replicated in Study 2. However, particular responses of a political candidate revealed no influences in connection with a real estate scandal. We explain our findings by applying the theory of planned behavior, attribution theory, and situational crisis communication theory.     

Adherence predictors in an Internet-based Intervention program for depression

Internet-delivered psychotherapy has been demonstrated to be effective in the treatment of depression. Nevertheless, the study of the adherence in this type of the treatment reported divergent results. The main objective of this study is to analyze predictors of adherence in a primary care Internet-based intervention for depression in Spain. A multi-center, three arm, parallel, randomized controlled trial was conducted with 194 depressive patients, who were allocated in self-guided or supported-guided intervention. Sociodemographic and clinical characteristics were gathered using a case report form. The Mini international neuropsychiatric interview diagnoses major depression. Beck Depression Inventory was used to assess depression severity. The visual analogic scale assesses the respondent’s self-rated health and Short Form Health Survey was used to measure the health-related quality of life. Age results a predictor variable for both intervention groups (with and without therapist support). Perceived health is a negative predictor of adherence for the self-guided intervention when change in depression severity was included in the model. Change in depression severity results a predictor of adherence in the support-guided intervention. Our findings demonstrate that in our sample, there are differences in sociodemographic and clinical variables between active and dropout participants and we provide adherence predictors in each intervention condition of this Internet-based program for depression (self-guided and support-guided). It is important to point that further research in this area is essential to improve tailored interventions and to know specific patients groups can benefit from these interventions.     

<Emphasis Type="Bold">Ultrahigh temporal resolution of visual presentation using gaming monitors and G-Sync</Emphasis>

Vision unfolds as an intricate pattern of information processing over time. Studying vision and visual cognition therefore requires precise manipulations of the timing of visual stimulus presentation. Although standard computer display technologies offer great accuracy and precision of visual presentation, their temporal resolution is limited. This limitation stems from the fact that the presentation of rendered stimuli has to wait until the next refresh of the computer screen. We present a novel method for presenting visual stimuli with ultrahigh temporal resolution (<1 ms) on newly available gaming monitors. The method capitalizes on the G-Sync technology, which allows for presenting stimuli as soon as they have been rendered by the computer’s graphics card, without having to wait for the next screen refresh. We provide software implementations in the three programming languages C++, Python (using PsychoPy2), and Matlab (using Psychtoolbox3). For all implementations, we confirmed the ultrahigh temporal resolution of visual presentation with external measurements by using a photodiode. Moreover, a psychophysical experiment revealed that the ultrahigh temporal resolution impacts on human visual performance. Specifically, observers’ object recognition performance improved over fine-grained increases of object presentation duration in a theoretically predicted way. Taken together, the present study shows that the G-Sync-based presentation method enables researchers to investigate visual processes whose data patterns were concealed by the low temporal resolution of previous technologies. Therefore, this new presentation method may be a valuable tool for experimental psychologists and neuroscientists studying vision and its temporal characteristics.     

Functions of Aggression and Peer Victimization in Elementary School Children: the Mediating Role of Social Preference

This study examined whether social preference was a mechanism that explained the relation between proactive and reactive aggression and peer victimization. Participants were 494 children in grades 2–5. Proactive and reactive aggression was assessed via a self-report measure and indices of social preference and peer victimization were assessed via a peer nomination inventory. Data was collected during the fall and spring of two academic years. The relations among aggression, social preference, and peer victimization varied as a function of aggression and gender. For girls, reactive aggression was a significant negative predictor of social preference. Findings also revealed social preference mediated the relation between reactive aggression and peer victimization for girls. This pathway did not hold for boys. There was some evidence that proactive aggression was negatively associated with peer victimization, but only for girls. Findings from the current study suggest social preference may be a key mechanism through which reactive aggression is associated with future victimization for girls. Boys’ aggression was not related to subsequent peer victimization. Future research and intervention efforts should consider gender differences and the function of aggression when investigating children’s peer victimization experiences.