Learned suppression of photopositive tendencies in Drosophila melanogaster

A task was designed to teach individual flies to avoid a lighted area after they had displayed an initial preference for it. The flies walked in a T-maze and chose between a lighted and a darkened alley leading, respectively, to a lighted and a darkened vial. Flies that were photopositive on a first trial were subjected to an aversive stimulus (a filter paper inserted into the lighted vial and wetted with a quinine solution), and they performed 16 training trials; they learned to avoid the lighted vial. The flies trained with water instead of quinine in the lighted vial still display avoidance of the lighted vial, but to a lesser extent. The flies trained with a dry filter paper in the lighted vial did not show any increase in avoidance during training. Like the flies trained with no quinine at all, those trained to avoid the lighted vial under a partial reinforcement condition (one half of the trials with quinine, the other half with a dry vial) did not master the task. Finally, removal of the quinine after an avoidance acquisition criterion was reached resulted in an extinction process.     

The ideomotor principle and motor sequence acquisition: Tone effects facilitate movement chunking

Participants practiced short sequences of key presses; sequence length and response-effect mapping were the independent variables. Contingent, distinct key-effect relations were contrasted with either contingent but uniform or no response effects. In Experiment 1, tone effects were relevant as response-specific stimuli and also as effects. The sequence length effect for the tones group was reduced. In Experiment 2, participants were informed about the sequences to be executed and then given varying amounts of preparation time before the start signal. A reduction in the sequence length effect was observed, and initiation times and mean interresponse time (IRTs) were generally reduced in the tone group. Preparation time could compensate for some but not all of the latency reducing influence of the tone effects. The results are discussed with reference to ideomotor approaches to motor control, i.e., the notion that actions are represented in sensory format.     

The relevance of the nature of learned associations for the differentiation of human memory systems

In a previous functional magnetic resonance imaging (fMRI) study we demonstrated an involvement of the medial temporal lobe (MTL) during an implicit learning task. We concluded that the MTL was engaged because of the complex contingencies that were implicitly learned. In addition, the basal ganglia demonstrated effects of a paralleled proceduralization of fixed stimulus-response associations. In the present study we directly tested the hypothesis that the MTL activation depends upon implementing the complex regularity in task material, whereas activation of basal ganglia does not. Therefore, we rearranged task material such that it did not contain any complex regularity. The statistical comparison of behavioral and fMRI data between the materials allowed for isolating effects that were directly related to the implicit learning process regarding the complex regularity. The results showed a reliable difference of fMRI signal limited to the MTL, indicating a specific functional role of the MTL in implicit learning of complex contingencies. Furthermore, no difference of BOLD (Blood-Oxygenation Level Dependent) signal in the basal ganglia and cerebellum were detected, supporting the assumption of a functional involvement of the structures in proceduralization of simple stimulus-response associations but not in implicitly learning complex relations. We therefore conclude that the nature of the learned associations is relevant for determining the neuronal focus of learning, rather than the accompanying awareness.     

Recognition of facial emotions in neuropsychiatric disorders

Recognition of facial emotions represents an important aspect of interpersonal communication and is governed by select neural substrates. We present data on emotion recognition in healthy young adults utilizing a novel set of color photographs of evoked universal emotions. In addition, we review the recent literature on emotion recognition in psychiatric and neurologic disorders, and studies that compare different disorders.     

The memory of noise

The memory of auditory random waveforms (i.e., noise) is a special case of auditory memory for sensory information. Five experiments are reported that evaluate the dynamics of this storage system as well as interactions with new input. Periodic waveforms can be discriminated from uncorrelated noise by naive listeners up to a cycle length of 20 s, with the major decline in performance between 5 and 10 s. Even single repetitions of a piece of the waveform can be detected up to a stimulus onset asynchrony (SOA) of 6 s. The capacity of this storage system is limited to a few items of, in total, a few hundred milliseconds length. Within this capacity, however, items do not interfere strongly. These results are compatible with the view that auditory sensory memory is a modality-specific module of short-term memory.     

John A. Snyder

Conclusion Wise counseling can relieve the anxiety and inner conflict of parents torn between the dread of their retarded offspring becoming a parent and the fear of an operation they believe to be illegal, immoral, and castrating.By knowing where to refer patients, clergymen can make it possible for some of these deprived members of society to find support and love within marriage without being overburdened by children they are not capable of rearing properly.     

Neural basis for sentence comprehension deficits in frontotemporal dementia

Many patients with frontotemporal dementia (FTD) have impaired sentence comprehension. However, the pattern of comprehension difficulty appears to vary depending on the clinical subgroup. The purpose of this study was to elucidate the neural basis for these deficits in FTD. We studied patients with two different presentations: Three patients with Progressive Non-Fluent Ahasia (PNFA), and five non-aphasic patients with a dysexecutive and social impairment (EXEC). The FTD patient subgroups were compared to a cohort of 11 healthy seniors with intact sentence comprehension. We monitored regional cerebral activity with blood oxygen level dependent (BOLD) functional magnetic resonance imaging (fMRI) while subjects read sentences featuring both a grammatically complex object-relative center-embedded clause and a long linkage between the head noun phrase (NP) and the gap where the NP is interpreted in the center-embedded clause. Subjects decided whether the agent of the action is a male or a female. Healthy seniors activated both ventral portions of inferior frontal cortex (vIFC) and dorsal portions of IFC (dIFC) in the left hemisphere, often associated with grammatical and working memory components of these sentences, respectively. PNFA patients differed from healthy controls since they have reduced activation of left vIFC, while EXEC patients have less recruitment of left dIFC. We conclude that FTD subgroups have distinct patterns of sentence comprehension difficulty in part because of selective interruptions of a large-scale neural network for sentence processing.     

A justification-suppression model of the expression and experience of prejudice

The authors propose a justification-suppression model (JSM), which characterizes the processes that lead to prejudice expression and the experience of one's own prejudice. They suggest that "genuine" prejudices are not directly expressed but are restrained by beliefs, values, and norms that suppress them. Prejudices are expressed when justifications (e.g., attributions, ideologies, stereotypes) release suppressed prejudices. The same process accounts for which prejudices are accepted into the self-concept The JSM is used to organize the prejudice literature, and many empirical findings are recharacterized as factors affecting suppression or justification, rather than directly affecting genuine prejudice. The authors discuss the implications of the JSM for several topics, including prejudice measurement, ambivalence, and the distinction between prejudice and its expression.