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141.
Jayme R. McReynolds Kyle Donowho Amin Abdi James L. McGaugh Benno Roozendaal Christa K. McIntyre 《Neurobiology of learning and memory》2010,93(3):312-321
Considerable evidence indicates that glucocorticoid hormones enhance the consolidation of memory for emotionally arousing events through interactions with the noradrenergic system of the basolateral complex of the amygdala (BLA). We previously reported that intra-BLA administration of a β-adrenoceptor agonist immediately after inhibitory avoidance training enhanced memory consolidation and increased hippocampal expression of the protein product of the immediate early gene activity-regulated cytoskeletal-associated protein (Arc). In the present experiments corticosterone (3 mg/kg, i.p.) was administered to male Sprague-Dawley rats immediately after inhibitory avoidance training to examine effects on long-term memory, amygdala norepinephrine levels, and hippocampal Arc expression. Corticosterone increased amygdala norepinephrine levels 15 min after inhibitory avoidance training, as assessed by in vivo microdialysis, and enhanced memory tested at 48 h. Corticosterone treatment also increased expression of Arc protein in hippocampal synaptic tissue. The elevation in BLA norepinephrine appears to participate in corticosterone-influenced modulation of hippocampal Arc expression as intra-BLA blockade of β-adrenoceptors with propranolol (0.5 μg/0.2 μL) attenuated the corticosterone-induced synaptic Arc expression in the hippocampus. These findings indicate that noradrenergic activity at BLA β-adrenoceptors is involved in corticosterone-induced enhancement of memory consolidation and expression of the synaptic-plasticity-related protein Arc in the hippocampus. 相似文献
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Diana M. Doumas Marianne King Christa Stallworth Polly Peterson Amanda Lundquist 《Journal of Addictions & Offender Counseling》2015,36(2):66-80
This study evaluated the effectiveness of a parent‐based intervention, the Parent Project, among 84 parents of at‐risk youth. Results indicated improvements in child management, family involvement, parent–child affective quality, substance use rules communication, and parental self‐efficacy at a 10‐week follow‐up. 相似文献
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One model of signal evolution is based on the notion that behaviours become increasingly detached from their original biological functions to obtain a communicative value. Selection may not always favour the evolution of such transitions, for instance, if signalling is costly due to predators usurping signal production. Here, we collected inertial movement sensing data recorded from multiple locations in free-ranging horses (Equus caballus), which we subjected to a machine learning algorithm to extract kinematic gestalt profiles. This yielded surprisingly rich and multi-layered sets of information. In particular, we were able to discriminate identity, breed, sex and some personality traits from the overall movement patterns of freely moving subjects. Our study suggests that, by attending to movement gestalts, domestic horses, and probably many other group-living animals, have access to rich social information passively but reliably made available by conspecifics, a finding that we discuss in relation with current signal evolution theories. 相似文献
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Heather Mae Rocha Juliann M. Savatt Erin Rooney Riggs Jennifer K. Wagner W. Andrew Faucett Christa Lese Martin 《Journal of genetic counseling》2018,27(2):470-480
Patients with newly-described or rare genetic findings are turning to social media to find and connect with others. Blogs, Facebook groups, and Twitter have all been reported as tools for patients to connect with one another. However, the preferences for social media use and privacy among patients, their families, and these communities have not been well characterized. To explore preferences about privacy and membership guidelines, an online survey was administered to two web-based patient registries, Simons Variation in Individuals Project (www.simonsvipconnect.org) and GenomeConnect (www.genomeconnect.org). Over a three-month period, invitations were sent to 2524 individuals and 103 responses (4%) were received and analyzed. Responses indicate that Facebook is the most popular resource accessed within this sample population (99%). Participants used social media to look for information about their diagnosis or test results (83%), read posts from rare disease groups or organizations (73%), participate in conversations about their diagnosis (67%), and connect with others to find support (58%). Focusing on privacy issues in social media, respondents indicate that membership and access impact the level of comfort in sharing personal or medical information. Nearly 60% of respondents felt uncomfortable sharing photos or medical information within a public Facebook group, whereas only 12% of respondents felt uncomfortable sharing in private group targeted to families alone. Using this preliminary data concerning social media use and privacy, we developed points for genetic counselors to incorporate when discussing available support resources for patients with a new, or rare, genetic diagnosis or genetic test result. Genetic counselors are trained to provide anticipatory guidance to families adapting to new genetic information, and are well-equipped to help patients consider their preferences about using social media as a source of information and support. 相似文献
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The creation of a postcolonial subject: The Chicago and Ateneo de Manila schools and the Peace Corps in the Philippines, 1960–1970 下载免费PDF全文
Christa Wirth 《Journal of the history of the behavioral sciences》2018,54(1):5-24
In the 1950s and 1960s scholars from the University of Chicago and the Ateneo de Manila created social scientific knowledge that helped establish the Peace Corps as a Cold War institution in the Philippines. Central were the social scientists at the University of Chicago and the Ateneo de Manila University who established a knowable postcolonial subject: “the Filipino,” which resulted from their research on Philippine values. In this context, the Ateneo/Chicago social scientists developed the “SIR,” the “smooth interpersonal relation” model that entails the notion that Filipinos and Filipinas particularly valued this nonconfrontational skill set among people. The SIR model was taught by social science experts to early Peace Corps volunteers as they prepared for their assignments in the Philippines. The article shows how the SIR model could cause distress and confusion as it was applied by Peace Corps volunteers in the Philippines. 相似文献
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