Default-mode network functional connectivity in aphasia: Therapy-induced neuroplasticity

Previous research on participants with aphasia has mainly been based on standard functional neuroimaging analysis. Recent studies have shown that functional connectivity analysis can detect compensatory activity, not revealed by standard analysis. Little is known, however, about the default-mode network in aphasia. In the current study, we studied changes in the default-mode network in subjects with aphasia who underwent semantic feature analysis therapy. We studied nine participants with chronic aphasia and compared them to 10 control participants. For the first time, we identified the default-mode network using spatial independent component analysis, in participants with aphasia. Intensive therapy improved integration in the posterior areas of the default-mode network concurrent with language improvement. Correlations between integration and improvement did not reach significance, but the trend suggests that pre-therapy integration of the default-mode network may predict therapy outcomes. Functional connectivity allows a better understanding of the impact of semantic feature analysis in aphasia.     

Visual Imagery Processing and Knowledge of Famous Names in Alzheimer's Disease and MCI

ABSTRACT

The study of memory for famous people and visual imagery retrieval was investigated in patients in the early stages of Alzheimer's disease (AD) and in the prodromal stage of AD, so-called Mild Cognitive Impairment (MCI). Fifteen patients with AD (MMSE ≥23), 15 patients with amnestic MCI (a-MCI) and 15 normal controls (NC) performed a famous names test designed to evaluate the semantic and distinctive physical features knowledge of famous persons. Results indicated that patients with AD and a-MCI generated significantly less physical features and semantic biographical knowledge about famous persons than did normal control participants. Additionally, significant differences were observed between a-MCI and AD patients in all tasks. The present findings confirm recent studies reporting semantic memory impairment in MCI. Moreover, the current findings show that mental imagery is lowered in a-MCI and AD and is likely related to the early semantic impairment.     

University Students’ Subjective Well-being: The Role of Autonomy Support from Parents, Friends, and the Romantic Partner

This study investigated the relations between perceived autonomy support from three significant sources (parents, friends, and the romantic partner) and university students’ subjective well-being (SWB) using two approaches: a variable-centered and person-centered approach. Participants were 256 university students (191 women, 65 men) involved in a romantic relationship. Results from both approaches revealed that students’ perception that significant individuals support their autonomy predicted higher levels of SWB. Furthermore, results from a person-centered approach suggested that students reported the highest levels of SWB when all sources were perceived to be highly autonomy supportive. Together, these findings support a sensitization process of need satisfaction. Implications for SWB and self-determination theory are discussed.     

Visual discrimination of species in dogs (Canis familiaris)

In most social interactions, an animal has to determine whether the other animal belongs to its own species. This perception may be visual and may involve several cognitive processes such as discrimination and categorization. Perceptual categorization is likely to be involved in species characterized by a great phenotypic diversity. As a consequence of intensive artificial selection, domestic dogs, Canis familiaris, present the largest phenotypic diversity among domestic mammals. The goal of our study was to determine whether dogs can discriminate any type of dog from other species and can group all dogs whatever their phenotypes within the same category. Nine pet dogs were successfully trained through instrumental conditioning using a clicker and food rewards to choose a rewarded image, S+, out of two images displayed on computer screens. The generalization step consisted in the presentation of a large sample of paired images of heads of dogs from different breeds and cross-breeds with those of other mammal species, included humans. A reversal phase followed the generalization step. Each of the nine subjects was able to group all the images of dogs within the same category. Thus, the dogs have the capacity of species discrimination despite their great phenotypic variability, based only on visual images of heads.     

Academic self-concept in high school: predictors and effects on adjustment in higher education

Academic self-concept is considered a relevant psychological construct influencing many educational outcomes directly or indirectly. Therefore, the major focus of the current study is on the predictors and effects of academic self-concept in late adolescence. First, we studied the simultaneous effects of individual, class-average and school-average achievement (i.e., assessed by school grades) on academic self-concept in the final year of high school, thereby replicating and extending previous research on the big-fish-little-pond effect model. Second, the predictive value of high school academic self-concept for academic adjustment and success in the first year of higher education was examined. The sample comprised 536 twelfth grade students (44% boys) recruited from 24 schools (67 classes) that were representative with regard to geographical region and educational network in Flanders. Structural equation modeling showed that, when examining the joint contribution of school- and class-average achievement, only class-average achievement was significantly and negatively associated with academic self-concept. Furthermore, a significant effect of academic self-concept in high school on academic adjustment and success in higher education (in addition to any effects of high school academic achievement) was found. These results highlight the importance of considering academic self-concept in educational research and policy.     

Syntactic processing in bilinguals: an fNIRS study

The study of the neural basis of syntactic processing has greatly benefited from neuroimaging techniques. Research on syntactic processing in bilinguals has used a variety of techniques, including mainly functional magnetic resonance imaging (fMRI) and event-related potentials (ERP). This paper reports on a functional near-infrared spectroscopy (fNIRS) study on syntactic processing in highly proficient young adult speakers of Portuguese (mother tongue) (L1) and French (second language) (L2). They made a syntactic judgment of visually presented sentences, which either did or did not contain noun-verb agreement violations. The results showed that syntactic processing in both languages resulted in significant activation in anterior frontal regions of the left hemisphere and in the temporal superior posterior areas of the right hemisphere, with a more prominent activation for L2 in some areas. These findings corroborate previously reported neuroimaging evidence, showing the suitability of fNIRS for the study of syntactic processing in the bilingual brain.     

Transfer of Skills in the Context of Non‐Suggestive Investigative Interviews: Impact of Structured Interview Protocol and Feedback

Two groups of police investigators were trained in the use of the National Institute of Child Health and Human Development (NICHD) interview protocol. After the training, one group (n = 8) received written feedback on each interview they conducted, whereas the other group (n = 11) did not. The objective of the study was, first, to evaluate the effect of NICHD protocol implementation on the types of questions and details provided by children and, second, to evaluate the impact of post‐training feedback. Interviewees were alleged sexual abuse victims between the ages of 3 and 14 years. Application of the NICHD protocol allowed interviewers to use more open‐ended questions and to obtain more details. The results show that providing feedback significantly increased the quality of the interviews. It is recommended that the NICHD protocol be used to interview child victims and witnesses and that feedback sessions be held with interviewers. Copyright © 2012 John Wiley & Sons, Ltd.     

Latency dependence of word-initial letter integration by the saccadic system

Two experiments are reported in which saccadic eye movements were examined when the eyes moved to words in which the properties of the word-initial letters differed. It was found that the effect of saccade latency on landing position depended on the properties of the word-initial letters. Under short saccade latencies, landing positions deviated toward the word beginning in the presence of orthographically irregular/informative beginning (OI/IB) letters. This result is interpreted as an influence of the orthographic encoding process that has detected an unusual letter grouping. With longer saccade latencies, an increase of the saccade size was observed for OI/IB words, whereas orthographically regular/uninformative beginning words did not show the effect. It is suggested that this may be a consequence of the dynamics of parafoveal word information processing.     

Health Behaviors and Psychological Distress in Women Initiating BRCA1/2 Genetic Testing: Comparison with Control Population

The study objective was to compare breast cancer screening practices, lifestyle behaviors and psychological distress among 640 women initiating BRCA1/2 testing to those among 9,498 similarly-aged women from the general population. Health behaviors and psychological distress were reported in a self-administered questionnaire at pre-test genetic counseling. Regression analyses indicate that high-risk women were more frequently performing breast cancer screening and, in the case of those previously diagnosed with cancer, were more likely to be non-smokers and physically active than women from general population. However, women initiating BRCA1/2 testing were significantly more distressed than controls. Globally, high-risk women seemed to be well informed about recommendations for women who are at high risk and to have access to screening adapted to their risk level. Given their significant psychological distress, providing minimal psychosocial support to all women undergoing BRCA1/2 testing at pre-test genetic counseling is relevant.