Reaction time and temporal serial judgment: corroboration or dissociation?]

Dissociations between a motor response and the subject's verbal report have been reported from various experiments that investigated special experimental effects (e.g., metacontrast or induced motion). To examine whether similar dissociations can also be observed under standard experimental conditions, we compared reaction times (RT) and temporal order judgments (TOJ) to visual and auditory stimuli of three intensity levels. Data were collected from six subjects, each of which served for nine sessions. The results showed a strong, highly significant modality dissociation: While RTs to auditory stimuli were shorter than RTs to visual stimuli, the TOJ data indicated longer processing times for auditory than for visual stimuli. This pattern was found over the whole range of intensities investigated. Light intensity had similar effects on RT and TOJ, while there was a marginally significant tendency of tone intensity to affect RT more strongly than TOJ. It is concluded that modality dissociation is an example of "direct parameter specification", where the pathway from stimulus to response in the simple RT experiment is (at least partially) separate from the pathway that leads to a conscious, reportable representation. Two variants of this notion and alternatives to it are discussed.     

Quantitative and qualitative analyses of clock drawings in Alzheimer's and Huntington's disease.

Although visuoconstructive impairment has been reported in both Alzheimer's (DAT) and Huntington's (HD) disease, there is little knowledge concerning how this cognitive deficit differs quantitatively and qualitatively in these two progressive dementias. To address this issue, the present study compared performances on the Clock Drawing Test (CDT: command and copy) of 25 DAT patients, 25 equally demented HD patients, and 25 elderly normal controls (NC). In the command condition, both patients groups were significantly impaired compared to the NC group. Although there was no significant difference between DAT and HD patients' total quantitative scores, a qualitative error analysis revealed a number of dissociations between the two patient groups. Graphic difficulties, very common in HD patients, were virtually absent in DAT patients; in contrast, conceptual errors were almost exclusively seen in DAT patients and were related to the severity of their dementia. Perseveration and "stimulus-bound" responses were also more frequent in DAT patients, and both groups made visuospatial errors. In the copy condition, the DAT, but not the HD, patients evidenced a marked improvement in performance. These results indicate that while both DAT and HD patients have significant visuoconstructive difficulties even in the early stages of their disorders, the specific cognitive processes underlying their quantitative impairments are quite different. It is possible that the DAT patients' conceptual errors are yet another indicator of the deterioration of their semantic knowledge.     

Memory with and without awareness: performance and electrophysiological evidence of savings.

Event-related potentials (ERPs) recorded on the scalp were shown to be sensitive indicators of the strength of a memory trace on both implicit and explicit tests of memory. In explicit recognition tests, the amplitude of a positive potential identified as P300 was larger for "old" than for "new" words regardless of whether the subject categorized the items correctly. This effect, however, was statistically reliable only when the recognition memory (d') was relatively high. In contrast to ERPs, the reaction times in explicit recognition were sensitive to accuracy but not to repetition. In implicit tests, lexical decisions to repeated words were faster than to newly presented words. The magnitude of the repetition effect varied neither with elapsed time since the last repetition nor with the number of previous repetitions. In contrast, the P300 elicited by the same words were sensitive to both lag and recency of repetition, suggesting that they were influenced by the episodic memory strength of the items.     

Dominance,sex, and leader emergence

A 3×2×2 incomplete factorial design was employed to test the effects of sex, dominance, and their interaction on leader emergence. The factors included dominance distribution (high/high, high/low, middle/middle), sex (male-female), and dyad composition (mixed sex-same sex). The subjects were all Caucasians and were pretested on the California Psychological Inventory Dominance Scale. The data revealed that dominance was a predictor of leader emergence in same-sex conditions where high-dominant individuals assumed the role of leader in much greater proportions than their low-dominant partners. In mixed-sex dyads, sex appeared to be a more potent predictor with males becoming leaders at levels greater than would be suspected given dominance levels.     

A PRESCRIPTION FOR GENERATING A NEW PARADIGM IN THE CONTEXT OF SCIENCE AND THEOLOGY

Abstract. Many centers are now active in the study of the interaction between science on the one hand and theology on the other. Suggestions are made as to how such study might be furthered. The central proposal in this paper is based on the author's experience in founding and, over many years, operating the Neurosciences Research Program (NRP). The "faculty" of this group were highly competent in many fields of science and were able to deal with many of the major issues. It is here further suggested that if an NRP-like organization were established, capable of productively interacting with both science and theology, it might well generate new concepts and possibly a new paradigm in this context.     

Spatial cognition and neighborhood use: the relationship in older adults.

Measures of spatial cognition, neighborhood knowledge, and neighborhood use from the research described by Walsh, Krauss, and Regnier (1981) were examined to determine if laboratory tests of spatial cognition were significant predictors of older adults' use of their neighborhoods. The overall results show that laboratory-based measures of spatial cognition and subjects' knowledge of their neighborhoods are both significant predictors of their use of neighborhood goods and services. The ability to learn and remember the location and orientation of objects, when contextual cues were not provided at test, was more predictive of the participants' neighborhood use than either the participants' number of years in the neighborhood or their mobility. Spatial memory as measured by the Educational Testing Service Building Memory task predicted neighborhood knowledge, which was predictive of neighborhood use.     

Age-related differences in three tests of visual imagery.

Adult age differences were explored on 3 short tests of the ability to generate and manipulate mental images. Age-related decrements were found in all 3 tests and were especially marked on the Clock Test. The tests are all reliable, as shown by test-retest reliability coefficients. Correlations also revealed that the Brooks Letter Test and the East-West Test appear to tap one common underlying ability, whereas the Clock Test measured a somewhat different ability. The East-West and Clock tests, in particular, may provide rapid and easily administered assessments of age-related changes in aspects of mental imagery.     

Crime and the elderly: a review of British and American research

Research into the victims of crime is of fairly recent origin and has been centred in America. However, a review of research into the experience of the elderly as the victims of crime, and their anxiety about crime, reveals a paradox. Numerous studies show that while the elderly are less likely to be the victims of crime than are the other age groups, they are among those who exhibit most anxiety over crime. The research is discussed in the context of theories of why the elderly appear as a low-risk group and in terms of an attempt to explain the paradox.     

Cocaine-induced brainstem seizures and behavior.

A variety of abnormal sensory/motor behaviors associated with electrical discharges recorded from the bilateral brainstem were induced in adult WKY rats by mechanical (electrode implants) and DC electrical current stimulations and by acute and chronic administration of cocaine. The electrode implant implicated one side or the other of the reticular system of the brainstem but subjects were not incapacitated by the stimulations. Cocaine (40 mg/kg) was injected subcutaneously for an acute experiment and subsequent 20 mg/kg doses twice daily for 3 days in a chronic study. Cocaine generated more abnormal behaviors in the brainstem perturbation group, especially the electrically perturbated subjects. The abnormal behaviors were yawning, retrocollis, hyperactivity, hypersensitivity, "beating drum" behavior, squealing, head bobbing, circling, sniffing, abnormal posturing, and facial twitching. Shifts in the power frequency spectra of the discharge patterns were noted between quiet and pacing behavioral states. Hypersensitivity to various auditory, tactile, and visual stimulation was present and shifts in the brainstem ambient power spectral frequency occurred in response to tactile stimulation. These findings suggest that the brainstem generates and propagates pathological discharges that can be elicited by mechanical and DC electrical perturbation. Cocaine was found to activate the discharge system and thus induce abnormal behaviors that are generated at the discharge site and at distant sites to which the discharge propagates. Cognitive functions may also be involved since dopaminergic and serotonergic cellular elements at the brainstem level are also implicated.