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91.
Douglas A. Grange Kathryn E. Hood Sandra C. Ikeda Cheryl L. Reed Byron C. Jones Michelle L. Block 《Aggressive behavior》1997,23(2):93-105
To explore genetic-developmental differences in the biobehavioral effects of induced illness, males from two lines of mice selectively bred for high or low levels of aggressive behavior were injected with endotoxin (Escherichia coli, LPS: 0.25 mg/kg, 1.25 mg/kg, or 2.5 mg, i.p.) or saline. Body temperature, weight, and locomotor activity were monitored immediately before and 8 and 24 hr after injection. Twenty-four hours after injection, social behaviors were assessed in a 10-min dyadic test, and hypothalamus, spleen, and serum were collected. In both lines, endotoxin treatment increased behavioral immobility ("freezing") and decreased social exploration. Other effects showed line differences: Males from the high-aggressive line had a lower threshold to endotoxin-induced effects on body temperature, weight loss, spleen weight, and corticosterone. Social reactivity (startle response to mild social investigation) increased in the high-aggressive line and decreased in the low-aggressive line after treatment. In the high-aggressive line only, endotoxin decreased attack frequency and increased latency to attack. The interactions between selected line (genotype) and endotoxin treatment (environment) demonstrate that genetic-developmental differences in social and aggressive behavior may indicate the extent to which immune stimuli (e.g., bacteria, viruses, cytokines) function as "biobehavioral stressors." Aggr. Behav. 23:93–105, 1997.© 1997 Wiley-Liss, Inc. 相似文献
92.
Holly J. Bowen Cheryl L. Grady Julia Spaniol 《Neuropsychology, development, and cognition. Section B, Aging, neuropsychology and cognition》2019,26(3):463-485
Affective processing is one domain that remains relatively intact in healthy aging. Investigations into the neural responses associated with reward anticipation have revealed that older and younger adults recruit the same midbrain reward regions, but other evidence suggests this recruitment may differ depending on the valence (gain, loss) of the incentive cue. The goal of the current study was to examine functional covariance during gain and loss feedback in younger and healthy older adults. A group of 15 older adults (mean age = 68.5) and 16 younger adults (mean age = 25.4) completed a revised Monetary Incentive Delay task (rMID; Knutson, Westdorp, Kaiser, &; Hommer, 2000) while in the fMRI scanner. The rMID is a reaction time task where successful performance, either gaining a reward or avoiding a loss, is defined by hitting a button during the brief presentation of a visual target. Participants receive gain and loss anticipation cues before each trial and feedback after each trial with four possible outcomes: +$5.00, +0.00, -$5.00, and -Affective processing is one domain that remains relatively intact in healthy aging. Investigations into the neural responses associated with reward anticipation have revealed that older and younger adults recruit the same midbrain reward regions, but other evidence suggests this recruitment may differ depending on the valence (gain, loss) of the incentive cue. The goal of the current study was to examine functional covariance during gain and loss feedback in younger and healthy older adults. A group of 15 older adults (mean age = 68.5) and 16 younger adults (mean age = 25.4) completed a revised Monetary Incentive Delay task (rMID; Knutson, Westdorp, Kaiser, & Hommer, 2000) while in the fMRI scanner. The rMID is a reaction time task where successful performance, either gaining a reward or avoiding a loss, is defined by hitting a button during the brief presentation of a visual target. Participants receive gain and loss anticipation cues before each trial and feedback after each trial with four possible outcomes: +$5.00, +0.00, -$5.00, and -$0.00. Using seed-voxel partial least squares analyses, with seed voxels in the caudate and ventromedial prefrontal cortex, whole-brain functional covariance revealed that younger and older adults engage the same network of regions to support general feedback processing. However, older adults engaged two additional networks to support processing of negative feedback, gain_miss (+0), loss_miss (-$5), and loss_hit (?0), specifically. These findings are in line with theories of a positivity effect in aging and may have implications for reward-stimulus learning and decision making following performance-contingent negative feedback. 相似文献
93.
Diffusion models (Ratcliff, 1978) make it possible to identify and separate different cognitive processes underlying responses in binary decision tasks (e.g., the speed of information accumulation vs. the degree of response conservatism). This becomes possible because of the high degree of information utilization involved. Not only mean response times or error rates are used for the parameter estimation, but also the response time distributions of both correct and error responses. In a series of simulation studies, the efficiency and robustness of parameter recovery were compared for models differing in complexity (i.e., in numbers of free parameters) and trial numbers (ranging from 24 to 5,000) using three different optimization criteria (maximum likelihood, Kolmogorov–Smirnov, and chi-square) that are all implemented in the latest version of fast-dm (Voss, Voss, & Lerche, 2015). The results revealed that maximum likelihood is superior for uncontaminated data, but in the presence of fast contaminants, Kolmogorov–Smirnov outperforms the other two methods. For most conditions, chi-square-based parameter estimations lead to less precise results than the other optimization criteria. The performance of the fast-dm methods was compared to the EZ approach (Wagenmakers, van der Maas, & Grasman, 2007) and to a Bayesian implementation (Wiecki, Sofer, & Frank, 2013). Recommendations for trial numbers are derived from the results for models of different complexities. Interestingly, under certain conditions even small numbers of trials (N < 100) are sufficient for robust parameter estimation. 相似文献
94.
The Experience in Personal Social Systems Questionnaire (EXIS.pers): Development and Psychometric Properties
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Christina Hunger Annette Bornhäuser Leoni Link Julian Geigges Andreas Voss Jan Weinhold Jochen Schweitzer 《Family process》2017,56(1):154-170
This study presents the theoretical background, development, and psychometric properties of the German and English versions of the Experience in Personal Social Systems Questionnaire (EXIS.pers). It assesses how the members of a personal social system experience their situation within that system. It is designed as a research tool for interventions in which only one member of the system participates (e.g., Family Constellation Seminars). The EXIS.pers was created to measure change on the individual level relating to one's own important personal social system. In Study 1, we used exploratory factor analysis (EFA) for latent variable identification of the original German EXIS.pers (n = 179). In Studies 2 and 3, we used confirmatory factor analysis (CFA) to examine the dimensionality of the German (n = 634) and English (n = 310) EXIS.pers. Internal consistencies and cross‐cultural structural equivalence were assessed. EFA indicated that a four‐factor model provided best fit for the German EXIS.pers. For both the German and English EXIS.pers, CFA provided the best fit for a five‐factor bi‐level model that included a general factor (Experience In Personal Social Systems) and four dimensions (Belonging, Autonomy, Accord, Confidence). Good internal consistencies, external associations, and cross‐cultural structural equivalence were demonstrated. This study provides first evidence for the German and English EXIS.pers as an economical and reliable measure of an individual's experience within his or her personal social systems. 相似文献
95.
The media, including television, newspapers, and popular films have been implicated in the facilitation of mental illness stigmatization by presenting negative and inaccurate depictions of various diagnoses. The current study examined the impact of film on participants’ knowledge, attitudes, and behaviors towards people with schizophrenia. A total of 106 participants completed questionnaires before and after viewing a 45-min film excerpt. Films viewed included a fear-based inaccurate, likeable-inaccurate, and an educational-accurate depiction of schizophrenia. There was also a control group. There were significant increases in stigmatizing attitudes for participants in the fear-based inaccurate group compared to the accurate and control group. Fear-based participants reported increased negative affect and endorsed statements suggesting that people with schizophrenia were unpredictable, dependent, and dangerous. These results provide support for the hypothesis that negative, inaccurate portrayals of severe mental illness enhance stigmatizing attitudes. Accurate film depictions, advocacy for social equality, and the continued education of individuals, clients, families, communities and organizations will help to mitigate the impact of films on mental illness stigmatization. 相似文献
96.
Carla Adksion‐Bradley Darrell Johnson JoAnn Lipford Sanders Lonnie Duncan Cheryl Holcomb‐McCoy 《Counseling and values》2005,49(2):147-154
In the field of counseling, there has been a growing awareness of the important role the Black church plays in African American communities. Although counseling professionals have begun recognizing the influence the Black church has in the lives of African Americans, there seems to be little information on how counselors can collaborate with African American congregations to meet the mental health needs of African American clients. The authors examine how counselors can use the psychological and social strengths of the Black church. Strategies and implications for collaborating with this institution are also discussed. 相似文献
97.
Georgiou GA Bleakley C Hayward J Russo R Dutton K Eltiti S Fox E 《Visual cognition》2005,12(1):145-158
Evidence suggests that anxiety is associated with a shift of visual attention toward threatening stimuli in the environment, such as facial expressions (Mogg & Bradley, 1999). More recent evidence, however, indicates that anxiety may be better characterized by a failure to rapidly disengage the visual attention system away from threat-related facial expressions (Fox, Russo, Bowles, & Dutton, 2001). The present study further investigates this delayed disengagement hypothesis. Results show that high trait-anxious individuals, in contrast to low trait-anxious individuals, take longer to classify peripheral target letters when fearful facial expressions were presented at fixation relative to sad, happy, or neutral expressions. These findings demonstrate a specific tendency to dwell on fear-relevant stimuli, as opposed to negative information in general. These findings are considered from an evolutionary perspective and the possible role of delayed disengagement from threat in the maintenance of anxiety states is also discussed. 相似文献
98.
99.
Women are underrepresented on the faculties and within the senior leadership ranks of academic health systems. Nevertheless, despite the continuing existence of career development challenges related to gender, it is possible for women to thrive professionally in these settings. Mentorship is extremely important, and it is argued that effective mentorship is facilitated by an understanding of both gender differences in social behaviors and the culture of academic health systems. Furthermore, a systems’ level emphasis on faculty diversity and the career development of women faculty is recommended. 相似文献
100.
Cheryl A. Logan 《Integrative psychological & behavioral science》2005,40(4):169-181
The breeding of albino rats had an enormous impact on experimental psychology in the twentieth century: Rats were, and for
many questions still remain, the “standard animal” for laboratory research in neurology, psychology, and physiology. Albert
Meyer was one of the figures most responsible for developing the albino rat as an experimental model. Despite Meyer’s pioneering
work with albino rats, his rat research has received only sparse attention. Little is known about the way in which the animal
served Meyer’s more famous psychiatric program. In this article, the author discusses the role that albino rats played in
Meyer’s animal research. He then turn to the contrast between the way in which Meyer viewed the animal’s role in research
and the way rats were later used as a laboratory “standard” to assure scientific generality. This comparison highlights the
changes that occurred in comparative psychology in the twentieth century, and it further clarifies some of the concerns associated
with the use of animal models today.
Reprinted from Jaan Valsiner (ed.).Thinking in Psychological Science: Ideas and Their Makers. Transaction Publishers.
Previously published inFrom Past to Future, Vol. 4(1),Animal models in human psychology: The uses of comparative methodologies, pp. 23–36. @ 2003 Frances L. Hiatt School of Psychology, Clark University. Author: Cheryl A. Logan, Ph.D., Departments of
Psychology and Biology, P. O. Box 26170, University of North Carolina at Greensboro, Greansboro, NC.
The author is graterful for permission to quote from the Adolf Meyer papers, which was granted by The Alan M. Chesney Medical
Archives at The Johns Hopkins Medical Institutions. 相似文献