Genetic studies of stuttering in a founder population

Genome-wide linkage and association analyses were conducted to identify genetic determinants of stuttering in a founder population in which 48 individuals affected with stuttering are connected in a single 232-person genealogy. A novel approach was devised to account for all necessary relationships to enable multipoint linkage analysis. Regions with nominal evidence for linkage were found on chromosomes 3 (P=0.013, 208.8 centiMorgans (cM)), 13 (P=0.012, 52.6 cM), and 15 (P=0.02, 100 cM). Regions with nominal evidence for association with stuttering that overlapped with a linkage signal are located on chromosomes 3 (P=0.0047, 195 cM), 9 (P=0.0067, 46.5 cM), and 13 (P=0.0055, 52.6 cM). We also conducted the first meta-analysis for stuttering using results from linkage studies in the Hutterites and The Illinois International Genetics of Stuttering Project and identified regions with nominal evidence for linkage on chromosomes 2 (P=0.013, 180-195 cM) and 5 (P=0.0051, 105-120 cM; P=0.015, 120-135 cM). None of the linkage signals detected in the Hutterite sample alone, or in the meta-analysis, meet genome-wide criteria for significance, although some of the stronger signals overlap linkage mapping signals previously reported for other speech and language disorders. EDUCATIONAL OBJECTIVES: After reading this article, the reader will be able to: (1) summarize information about the background of common disorders and methodology of genetic studies; (2) evaluate the role of genetics in stuttering; (3) discuss the value of using founder populations in genetic studies; (4) articulate the importance of combining several studies in a meta-analysis; (5) discuss the overlap of genetic signals identified in stuttering with other speech and language disorders.     

The Developmental Perspective in Integral Counseling

The process of making meaning is a core determinant of human experience. Understanding this process, developmentally, is a vital part of integral counseling. In this article, the authors introduce the concept of ego development stages as increasingly complex and flexible systems of meaning making. An understanding of ego development stages can help counselors to assist clients in a way that recognizes that people not only come in different “types” but also differ significantly in the level of their meaning‐making capacity.     

The effect of a major event on stereotyping: terrorist attacks in Israel and Israeli adolescents' perceptions of Palestinians,Jordanians and Arabs

This study examines the effect of a major event (terrorist attacks) on the stereotypic perceptions, attitudes and affects of 119 Israeli adolescents (56 males and 63 females of 5th and 8th grades) toward three target groups: (a) Palestinians, who still have conflictive relations with the Israelis (Palestinian extremists carried out the attacks), (b) Jordanians, who have peaceful relations with the Israelis and (c) Arabs, in general, who are considered a subcategory including Arabs of all nations. The questionnaires were administered to the same adolescents three times: during a relatively peaceful spell in Israeli–Palestinian relations; one day following two terrorist attacks, and three months thereafter. In the last administration adolescents' need for closure was also measured. Adolescents' perceptions, attitudes and affect toward the three target group were differentiated—relating to Palestinians most negatively and to Jordanians most positively. Also, following the terrorist attacks, stereotypic perceptions and attitudes changed in a negative direction, in relation to all the three groups; again with expressed differentiation among the three groups. In the third measurement, some measures remained negative, but some changed to be more positive. Only few effects of age were detected and several significant correlation with need for closure were found. These results indicate that stereotypes and attitudes toward outgroups are context‐dependent, influenced by events; thus they serve as ‘a seismograph’ to the quality of intergroup relations at any given time. Copyright © 2001 John Wiley & Sons, Ltd.     

Ethnic Diversity and the Use of Humor in Counseling: Appropriate or Inappropriate?

Humor can reflect the healthy release of feelings during the counseling process, the type of emotional release that leads to significant therapeutic gains. It can also be a disturbing distraction, possibly causing early termination, if used inappropriately. Counselors need to exert particular caution before attempting to apply humor in working with a client from a culture different from the counselor's. This article explores the available literature and offers contributions on the subject from 4 “ethnically diverse” perspectives. Finally, a general approach based on existential theory is presented along with 5 general conditions to ascertain the appropriate use of humor.     

Exploring Ethnic,Gender, and Sexual Orientation Variables in Supervision: Do They Really Matter?

This study explored discussions of cultural variables in supervision and their influence on supervisory satisfaction and working alliance. Results indicated limited discussions occurred, but when these discussions did occur, supervisees reported enhanced supervisory working alliance and increased satisfaction with supervision. These findings highlight the importance of supervisors initiating discussions of cultural variables. Este estudio exploró discusiones sobre variables culturales y su influencia en la satisfacción y alianza de supervisión. Los resultados indicaron discusiones limitadas, pero cuando estas ocurrieron, los supervisados reportaron un aumento en la alianza de trabajo y satisfacción con la supervisión. Estos resultados hacen notable la importancia de que los supervisores inicien discusiones sobre los variables culturales.     

The Role of Abstract and Specific Knowledge in the Formation of Product Judgments: An Analogical Learning Perspective

Prior research has assumed that existing knowledge exerts its influence on consumer judgments primarily through abstract knowledge structures. Consequently, little attention has been given to the possibility that judgments may, under certain circumstances, be influenced by knowledge associated with more specific knowledge structures. This article examines the factors responsible for determining the impact of abstract versus specific knowledge on consumer judgments. Based on the Consumer Learning by Analogy model (CLA model; Gregan‐Paxton & John, 1997), it is argued that the relative influence of abstract and specific knowledge is a function of (a) the relation between the new product and existing knowledge and (b) the nature of consumer's knowledge. These ideas were tested in a series of experiments in which participants were required to judge a new product that varied in its relation to an existing product or brand. In this context, the influence of specific knowledge was most evident when participants were able to construct an attribute mapping, but not a relational mapping, to link the novel product to a familiar brand exemplar. When it was possible to construct a relational mapping, a more abstract knowledge structure, such as a schema, was retrieved and used as the basis of product judgments.