Auditory hallucinations in acute stroke

Auditory hallucinations are uncommon phenomena which can be directly caused by acute stroke, mostly described after lesions of the brain stem, very rarely reported after cortical strokes. The purpose of this study is to determine the frequency of this phenomenon. In a cross sectional study, 641 stroke patients were followed in the period between 1996-2000. Each patient underwent comprehensive investigation and follow-up. Four patients were found to have post cortical stroke auditory hallucinations. All of them occurred after an ischemic lesion of the right temporal lobe. After no more than four months, all patients were symptom-free and without therapy. The fact the auditory hallucinations may be of cortical origin must be taken into consideration in the treatment of stroke patients. The phenomenon may be completely reversible after a couple of months.     

Goldfish (Carassius auratus) matching geometric and featural cues: a reinterpretation of some of the data of Vargas, López, Salas, and Thinus-Blanc (2004)

Vargas, López, Salas, and Thinus-Blanc showed that goldfish (Carassius auratus) can use both geometric and featural cues in relocating a target corner in a rectangular enclosure. When featural cues (arrangement of striped walls) were put in conflict with geometric cues, results differed according to target location during training. Vargas, López, et al. explained the results of their cue conflict in terms of 2 different strategies: mapping and cue guidance. I provide an alternative, more parsimonious interpretation in which the same strategy of attempting to match as many cues as possible applies to both cases.     

如何认识抗生素这把"双刃剑"——谈抗生素临床应用体会

抗生素是临床最常用的药物之一,它跟其他药物一样,也具有利弊双重性.本文结合临床之所见,从反面浅谈抗生素使用的一些体会.通过介绍抗生素目前面临的问题,提出临床上医生如何规范应用抗生素,以使抗生素发挥最好疗效而弊端降至最低.     

Attributional style and self-esteem as predictors of psychological well being

Background: this study sets out to examine to what extent attributional style (internal, stable, global) and self-esteem predicted positive affect and self-reported happiness in a normal, non-clinical, population of young people in their early 20s. Method: 88 participants completed five questionnaires: Attributional Style Questionnaire (ASQ in both positive and negative situations), Bradburn Affect Scales (Positive Affect, Negative Affect, and Affect Balance Scale), Rosenberg Self-Esteem Scale Gurin Happiness Measure, and Oxford Happiness Inventory (OHI). Results: regressional analysis showed that the ASQ was the significant predictor of happiness accounting for 18% of variance. The ASQ in positive and negative situations was significantly inversely correlated with self-esteem. Further, with happiness (the OHI) as dependent variable and attributional style, self-esteem, and demographic variables as independent variables, self-esteem and attributional style (in positive situations) were the significant predictors of happiness accounting for 55% of the total variance. Conclusion: the results indicated that optimistic attributional style in positive situations was a stronger predictor of self-reported happiness than optimistic attributional style in negative situations. The implications of the findings are discussed in terms of cognitive strategies for changing pessimism into optimism thus enhancing happiness or psychological well-being.     

Voluntarily-generated unimanual preparation is associated with stopping success: evidence from LRP and lateralized mu ERD before the stop signal

According to the race models of the stop-signal paradigm, stopping success (successful vs. unsuccessful stopping) is attributed to the finishing times of a go and a stop process. In addition to those factors involving processing times, in the present study we sought to use electrophysiological measures to find factors involving activations that could affect stopping success. We hypothesized that voluntarily-generated unimanual preparation would be a factor. To assess voluntarily-generated unimanual preparation in the stop-signal paradigm, we used a selective-stopping task without any precue. The selective-stopping task also allowed us to assess reaction times (RTs) even when stopping was successful. We demonstrated shorter RTs in signal-respond (i.e. unsuccessful stopping) than in signal-inhibit (successful stopping) trials, as is predicted by the race models. More importantly, we also demonstrated different pre-signal lateralized readiness potentials between the two types of trials and larger lateralized mu ERD in signal-respond than in signal-inhibit trials, suggesting that voluntarily-generated unimanual preparation affects stopping success. In addition to what is described in the race models of the stop-signal paradigm, the present results therefore demonstrated measures of pre-signal activations that could influence stopping success.     

The Explanation Proffering Norm of Moral Assertion

In recent years, much attention has been given to the epistemic credentials of belief based on moral testimony. Some people think pure moral deference is wrong, others disagree. It comes as a surprise, however, that while the epistemic responsibilities of the receiver of moral testimony have been closely scrutinized, little to no discussion has focused on the epistemic duties of the speaker. This paper aims to supply this lack: it defends a function-first account of the normativity of moral assertion. According to this view, in virtue of its function of reliably generating understanding in the audience, a moral assertion that p needs be knowledgeable and accompanied by a contextually appropriate explanation why p.     

The epistemic normativity of conjecture

Philosophical Studies - This paper has two aims: (1) it develops and defends a fully-fledged account of the epistemic normativity of conjecture (2) it goes sharply against orthodoxy, in arguing...