医学模式的转变与胃食管反流病的思考

胃食管反流病（GERD）是消化科门诊最常见的疾病之一,具有慢性复发性倾向,严重影响人们的生活质量。目前认为本病是一种多因素的心身疾病,随着传统生物医学模式向生物-心理-社会医学模式的转变,要求我们要自觉地运用辩证唯物主义观点,从系统论出发,应用发展的观点,注重医学模式的转变,审慎制定治疗方案。     

技能性知识与体知合一的认识论

近年来,现象学、科学知识社会学以及关于人工智能的哲学研究对传统科学认识论提出了挑战。这些研究成果虽然主旨各不相同,但都不约而同地涉及到关于技能性知识(skillful knowledge)的讨     

Chinese characters elicit face-like N170 inversion effects

Recognition of both faces and Chinese characters is commonly believed to rely on configural information. While faces typically exhibit behavioral and N170 inversion effects that differ from non-face stimuli (Rossion, Joyce, Cottrell, & Tarr, 2003), the current study examined whether a similar reliance on configural processing may result in similar inversion effects for faces and Chinese characters. Participants were engaged in an orientation judgment task (Experiment 1) and a one-back identity matching task (Experiment 2). Across two experiments, the N170 was delayed and enhanced in magnitude for upside-down faces and compound Chinese characters, compared to upright stimuli. The inversion effects for these two stimulus categories were bilateral for latency and right-lateralized for amplitudes. For simple Chinese characters, only the latency inversion effects were significant. Moreover, the size of the right-hemisphere inversion effects in N170 amplitude was larger for faces than Chinese characters. These findings show the N170 inversion effects from non-face stimuli closely parallel effects seen with faces. Face-like N170 inversion effects elicited by Chinese compound characters were attributed to the difficulty of part-whole integration as well as the disrupted regularity in relational information due to inversion. Hemispheric difference in Chinese character processing is also discussed.     

增龄性记忆改变规律及影响因素的研究

本研究用多维记忆量表对280名50～91岁的老年人做了测查,同时收集了一般资料,以探讨增龄性记忆改变的规律和年龄、教育和职业等因素对增龄性记忆改变的影响。结果表明：随年龄增长,各记忆组合分和分测验成绩均呈下降趋势,外显记忆成绩在70岁后呈快速下降,内隐记忆和日常生活记忆在75岁后才有明显下降;记忆总分、外显记忆和日常生活记忆均受年龄和教育的影响,内隐记忆不受教育的影响。结果提示老年人记忆随年龄增长呈渐渐下降,不同记忆功能开始下降的年龄和下降速率不同,教育对增龄性记忆改变有保护作用。     

Transformational Leadership and Organisational Citizenship Behaviour: A Moderated Mediation Model of Leader‐Member‐Exchange and Subordinates' Gender

Transformational leadership (TL) enhances follower Organizational Citizenship Behavior (OCB) as mediated by leader‐member exchange (LMX). However, the strength of the positive associations among TL, LMX and OCB is subject to significant variability. Accordingly, we draw on several theories (self‐identity, role congruency, self‐concept, and social exchange) to propose that followers' gender moderates the relationships between all three of these variables. We argue differences in societal expectations and/or underlying motivation combine to make leadership of lesser importance to OCB among females than males. Using 202 supervisor‐subordinate dyads from Taiwan, a moderated mediation model of TL‐LMX‐OCB, with subordinate gender as a moderator, was tested. As hypothesised, each of the positive associations among TL, LMX and OCB were weaker for females than for males, thus accounting for some of the variability in the strength of the associations typically observed. Relatedly, although LMX fully mediated the TL‐OCB relationship in the entire sample, this effect was not observed among female subordinates. Further research is required to assess the degree to which these findings apply beyond the Confucian Asian societal cluster.     

A brief version of the geriatric depression scale for the chinese

Elderly persons (N=310) attending outpatient psychiatric clinics were given an interview on the 30-item Geriatric Depression Scale (T. L. Brink et al., 1982; J. A. Yesavage et al., 1983) and received an independent psychiatric evaluation. A 3-step binary logistic regression showed that 2 items measuring positive affect and 2 others measuring negative affect combined to produce diagnostic performance comparable with the full scale. This result was cross-validated on a different sample (N=134). A hierarchical measurement model in which the 4 items tapped 2 first-order factors (positive and negative affect), which in turn tapped a higher order construct of depression, provided excellent fit to the data.     

Amygdala and hippocampal activity during acquisition and extinction of human fear conditioning

Previous functional magnetic resonance imaging (fMRI) studies have characterized brain systems involved in conditional response acquisition during Pavlovian fear conditioning. However, the functional neuroanatomy underlying the extinction of human conditional fear remains largely undetermined. The present study used fMRI to examine brain activity during acquisition and extinction of fear conditioning. During the acquisition phase, participants were either exposed to light (CS) presentations that signaled a brief electrical stimulation (paired group) or received light presentations that did not serve as a warning signal (control group). During the extinction phase, half of the paired group subjects continued to receive the same treatment, whereas the remainder received light alone. Control subjects also received light alone during the extinction phase. Changes in metabolic activity within the amygdala and hippocampus support the involvement of these regions in each of the procedural phases of fear conditioning. Hippocampal activity developed during acquisition of the fear response. Amygdala activity increased whenever experimental contingencies were altered, suggesting that this region is involved in processing changes in environmental relationships. The present data show learning-related amygdala and hippocampal activity during human Pavlovian fear conditioning and suggest that the amygdala is particularly important for forming new associations as relationships between stimuli change.     

Self-monitoring without awareness: using mimicry as a nonconscious affiliation strategy

This research sought to extend the current conceptualization of self-monitoring by examining whether self-monitoring motives and behaviors can operate outside of conscious awareness. Two studies examined nonconscious mimicry among high and low self-monitors in situations varying in affiliative cues. Participants interacted with a confederate who shook her foot (Study 1) or touched her face (Study 2). In both studies, high self-monitors were more likely to mimic the confederate's subtle gestures when they believed the confederate to be a peer (Study 1) or someone superior to them (Study 2). Low self-monitors mimicked to the same degree across conditions. Thus, when the situation contains affiliative cues, high self-monitors use mimicry as a nonconscious strategy to get along with their interaction partner.