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91.
Hyperactivity and Learning Deficits in Transgenic Mice Bearing a Human Mutant Thyroid Hormone β1 Receptor Gene 下载免费PDF全文
Michael P. McDonald Rosemary Wong Gregory Goldstein Bruce Weintraub Sheue-yann Cheng Jacqueline N. Crawley 《Learning & memory (Cold Spring Harbor, N.Y.)》1998,5(4):289-301
Resistance to thyroid hormone (RTH) is a human syndrome mapped to the thyroid receptor β (TRβ) gene on chromosome 3, representing a mutation of the ligandbinding domain of the TRβ gene. The syndrome is characterized by reduced tissue responsiveness to thyroid hormone and elevated serum levels of thyroid hormones. A common behavioral phenotype associated with RTH is attention deficit hyperactivity disorder (ADHD). To test the hypothesis that RTH produces attention deficits and/or hyperactivity, transgenic mice expressing a mutant TRβ gene were generated. The present experiment tested RTH transgenic mice from the PV kindred on behavioral tasks relevant to the primary features of ADHD: hyperactivity, sustained attention (vigilance), learning, and impulsivity. Male transgenic mice showed elevated locomotor activity in an open field compared to male wild-type littermate controls. Both male and female transgenic mice exhibited impaired learning of an autoshaping task, compared to wild-type controls. On a vigilance task in an operant chamber, there were no differences between transgenics and controls on the proportion of hits, response latency, or duration of stimulus tolerated. On an operant go/no-go task measuring sustained attention and impulsivity, there were no differences between controls and transgenics. These results indicate that transgenic mice bearing a mutant human TRβ gene demonstrate several behavioral characteristics of ADHD and may serve a valuable heuristic role in elucidating possible candidate genes in converging pathways for other causes of ADHD. 相似文献
92.
Previous studies have shown that distraction may either increase or decrease attitude change. The present experiment, designed to reconcile earlier findings, was based on the hypothesis that distraction should interfere with message reception but also increase yielding to the message. Distraction should thus increase attitude change to a simple message (one which is easily understood but not very convincing), but decrease attitude change to a complex message (one which is difficult to understand but convicing if understood). Subjects beard messages on two topics, sometimes while distracted by a tape recording of music and sometimes not. Message complexity was successfully manipulated for one of the topics. The results support a model of attitude change which considers the effects of independent variables on both reception and yielding. 相似文献
93.
Robert S. Davidon Mei-Fang Hsieh Cheng 《Quarterly journal of experimental psychology (2006)》1964,16(3):277-281
In the study of active tactile-kinesthetic space perception apparent distance has been found to vary as a function of the direction of the line segment in a horizontal plane. The present data indicate that the error is not consistently related to the same frame of reference as the visual illusion. Rather, with movement of the extended arm to determine the relative distances between pairs of points, radial distances are overestimated in relation to tangential ones, whether parallel or perpendicular to the medial plane. Interpretations are in terms of kinesthetic stimulus patterns and the structure of perceptual representation. 相似文献
94.
Despite the critical role affect can play in mentoring, a type of close relationships in the workplace, affect has not received much attention in existing mentoring research. Drawing upon Byrne's affect-centered model of attraction, we examined the relationships among mentors' moods during their interaction with protégés, mentors' liking of protégés, and mentoring support received by protégés. Moreover, we also examined the moderating effect of protégés' emotional intelligence (EI) on the relationship between mentors' moods and liking. Based on data collected from 237 ongoing formal mentoring dyads, we found that mentors' positive moods were positively related, and negative moods were negatively related, to mentoring support received through mentors' liking. Furthermore, protégés' EI only moderated the positive relationship between mentors' positive moods and liking such that the positive relationship was stronger for protégés low on EI. Theoretical and practical implications of the findings are discussed. 相似文献
95.
Do incompatible arguments cause extensive processing in the evaluation of arguments? The role of congruence between argument compatibility and argument quality 下载免费PDF全文
Cheng‐Hong Liu Hung‐Wei Lee Po‐Sheng Huang Hsueh‐Chih Chen Scott Sommers 《British journal of psychology (London, England : 1953)》2016,107(1):179-198
Previous studies have demonstrated that arguments incompatible with prior beliefs are subjected to more extensive refutational processing, scrutinized longer, and judged to be weaker than arguments compatible with prior beliefs. However, this study suggests whether extensive processing is implemented when evaluating arguments is not decided by argument compatibility, but by congruence between two evaluating tendencies elicited by both argument compatibility and argument quality. Consistent with this perspective, the results of two experiments show that relative to congruent arguments, participants judged arguments eliciting incongruent evaluating tendencies as less extreme in strength, spent more time, and felt more hesitant generating strength judgments for them. The results also show that it is mainly incongruent arguments, not congruent arguments, whose strength ratings were more closely associated with the perceived personal importance of the issue, which intensified the tendency to evaluate arguments depending on argument compatibility. These results suggest that it is the incongruity between argument compatibility and argument quality, and not simply the argument compatibility, that plays a more important role in activating an extensive processing in the evaluation of arguments. 相似文献
96.
Do CEOs Matter to Firm Strategic Actions and Firm Performance? A Meta‐Analytic Investigation Based on Upper Echelons Theory 下载免费PDF全文
What roles do CEOs play in firm performance? To address this question, the management field has accumulated a substantial amount of research over the past 3 decades built on upper echelons theory (UET), which posits that CEO characteristics manifest in firm strategic actions and, in this way, future firm performance. Hence, there is a need to systematically amass and take stock of prior empirical findings for UET testing and development. We use meta‐analytic techniques to synthesize prior UET research on the relationships among commonly studied CEO characteristics, firm strategic actions, and future firm performance. Based on 308 studies, meta‐analytic results generally support UET's predictions with a few exceptions: CEO characteristics (i.e., tenure, formal education, prior career experience, and positive self‐concept) are significantly associated with firm strategic actions, which in turn are significantly related to future firm performance. Moreover, CEO characteristics (i.e., age, tenure, formal education, and prior career experience) are positively related to future firm performance. In addition, fine‐grained analyses have revealed interesting and important relationships between specific measures of CEO characteristics (e.g., CEO prior task experience) and firm outcomes (e.g., firm strategic actions that match with CEO prior task experience). Implications for theory, future research, and practice are discussed. 相似文献
97.
98.
The present study aimed to examine the child‐rearing practices in Chinese families in Beijing and Hong Kong. The sample consisted of 89 mothers in Beijing and 45 mothers in Hong Kong. The mothers were instructed to respond to the Child‐rearing Practice Report (CRPR) in Q‐sort format. Some of the item clusters were combined to produce the authoritarian and authoritative disciplinary styles. The results indicated that mothers in Hong Kong were more likely to adopt an authoritarian child‐rearing pattern than mothers in Beijing; however, the two groups did not differ in authoritative child‐rearing style. The results also showed that mothers in Hong Kong controlled their children more than their counterparts in Beijing, and they were less inclined to show affection towards their children; mothers in Beijing emphasized their children's achievement much more than their Hong Kong counterparts. The findings suggest that Chinese parental disciplinary styles may be quite different in various regions of Chinese societies. Such variance across different geopolitical locations within the same cultural background has been ignored in past cross‐cultural research. 相似文献
99.
为探讨大学生人格特质与道德认同的关系,及其法律意识在二者关系之间的调节作用,采用法律意识量表、道德认同量表和大五人格量表对1878名大学生进行了调查。结果显示:(1)尽责性、宜人性、开放性和外向性与道德认同、法律意识呈显著的正相关;神经质与道德认同、法律意识呈显著的负相关。(2)人格特质、道德认同、法律意识表现出了显著的性别差异,同时尽责性对道德认同的影响也存在着显著的性别差异。(3)法律意识在尽责性与宜人性对大学生道德认同的影响中起着负向调节作用。本研究结果提示,应该尊重人格特质的个体特异性,在高校进行专业的法制教育和法律意识培养,提高个体的道德认同水平。 相似文献
100.
婴儿面孔图式效应是促进早期亲子关系形成的一种先天本能反应, 该效应一直被认为主要是受婴儿面孔结构的影响。但近年来表情对该效应的影响开始得到关注, 在以成人面孔为基线的条件下, 婴儿面孔图式效应量会因表情不同而有所变化, 表现出中性婴儿面孔图式效应最强的现象。鉴于目前对该现象的成因及其神经机制知之甚少, 所以本项目拟先建立一套婴儿与成人同面孔多表情图片系统; 然后以此为基础, 分别考察面孔表情不确定性是否会调节成人对不同表情婴儿面孔的偏好和注意偏向, 并探究其相应神经机制, 促进养育脑研究在我国的开展。 相似文献