Effect of socioeconomic status on aphasia severity and recovery

Low levels of educational attainment and low socioeconomic status have been significantly linked to poor health and increased incidence of disease, including Alzheimer's disease and diseases of the cardiovascular, pulmonary, renal, and gastrointestinal systems. Our goal in the present study was to determine the degree to which educational level and socioeconomic status influence initial severity of aphasia and subsequent recovery. We evaluated the records of 39 persons with aphasia twice: at about 4 months and 103 months postonset. We found early severity of aphasia to be significantly greater for subjects in the lower educational and occupational groups. However, rate of recovery (the slope of the recovery curve) was the same regardless of educational or occupational status.     

Adverse-effect profile of kava

The use of alternative therapies has increased substantially over the last decade, particularly for more chronic conditions such as anxiety. Among the most widely used treatments are medicinal herbs, or phytomedicines, such as kava (Piper methysticum), which has demonstrated anxiolytic activity in both animal models and clinical samples. Kava has several advantages over conventional pharmacologic treatments for anxiety--in clinical settings it has been associated with better tolerability and lack of physiologic dependence and withdrawal. However, phytomedicines are not rigorously regulated in the United States and systematically collected safety data are very limited. These issues are a leading concern regarding the safety of medicinal herbs such as kava. In this report, the safety profile for kava is provided, including findings from a study of its use in generalized anxiety disorder. Safety parameters assessed include occurrence of adverse events, withdrawal symptoms, effect on heart rate, blood pressure, laboratory assessments, and sexual function. No differences were found between kava and placebo on any of the parameters evaluated. The data support the safety of kava in treating anxiety at 280 mg kava lactones/day for 4 weeks.     

Adapting to Context in Community-Based Participatory Research: “Participatory Starting Points” in a Chinese Immigrant Worker Community

Community-based participatory research (CBPR) is increasingly being used to better understand and improve the health of diverse communities. A key strength of this research orientation is its adaptability to community contexts and characteristics. To date, however, few studies explicitly discuss adaptations made to CBPR principles and processes in response to community context and partners’ needs. Using data from our CBPR study, the San Francisco Chinatown Restaurant Worker Health and Safety Project, and drawing from literature on immigrant political incorporation, we examine the links between the contexts of the Chinese immigrant worker community, adaptations made by our collaborative, and study outcomes. In particular, we explore the concepts of contexts of reception and participatory starting points, which may be especially relevant for partnerships with immigrant communities whose members have historically had lower rates of civic and political participation in the US. We discuss contextual findings such as worker partner accounts of language barriers, economic and social marginalization, and civic skills and participation, as well as subsequent adaptations made by the partnership. We also describe the relative effectiveness of these adaptations in yielding equitable participation and building partners’ capacity. We conclude by sharing lessons learned and their implications for CBPR and partnerships with immigrant communities more broadly.     

False pretense and deviant exploitation: Fortunetelling as a con

This paper presents a dramaturgical analysis of the backstage manipulations carried out by practitioners of the deviant occupation known as fortunetelling. It is generally believed that con games require a dishonest victim, although many practitioners manipulate their impressions with clients who are seeking a service rather than a profit. The group of fortunetellers included in this study are nonbelievers and hence fundamentally misrepresent themselves to their clients. Drawing upon depth interviews with 21 non‐Gypsy fortunetellers, including two key informants, six backstage routines are analyzed. Each routine in the fortuneteller's performance presents the client with a frontstage definition of the activity designed to sell more and more “psychic services.” The implications of the dramaturgical analysis of con games are discussed.     

Irrationality and egoism in Hegel’s account of right

ABSTRACT

Many interpreters argue that irrational acts of exchange can count as rational and civic-minded for Hegel – even though, admittedly, the persons who are exchanging their property are usually unaware of this fact. While I do not want to deny that property exchange can count as rational in terms of ‘mutual recognition’ as interpreters claim, this proposition raises an important question: What about the irrationality and arbitrariness that individuals as property owners and persons consciously enjoy? Are they mere vestiges of nature in Hegel’s system, or do they constitute a simple yet valid form of freedom that is not only a part of Hegel’s rational system of right, but its necessary starting point? I will argue the latter: The arbitrary, purely egoist self-definition of property owners is the simplest possible type of freedom for Hegel, which he dissects in order to show how the very arbitrary self-definition implicitly relies on an identity between persons, and hence foreshadows the more social forms of freedom Hegel will discuss later in his book. I make this argument by highlighting Hegel’s references to his discussion of atoms and freedom in his Logic of Being.     

The German Reformation and the Mathematization of the Created World

This article explores the emergence of mathematics and mathematical method as a means of defining authoritative truth in the thought of some scholars in the German Reformation. Against the background of Martin Luther's critique of Aristotelian philosophy, Philip Melanchthon presented mathematics as an ideal discipline for preparing the mind to understand God. His approach drew on the work of humanist mathematicians such as Regiomontanus. It finds resonances in the work of the Basel humanist Simon Grynaeus, and (in a less mathematically informed way) in the thought of Peter Ramus. These discussions about the divine nature and certainty of mathematical truth formed the context within which Johannes Kepler's Platonist astronomy emerged.     

Increased Proportion of Farm Animal Names Generated by Patients with Alzheimer's Disease: What Does it Mean?

Binetti et al. (1995) reported that patients with Alzheimer's disease (AD) produced fewer semantic clusters than controls on the Animals Fluency task; of the clusters produced, 80% involved farm animals for the patients with AD compared to 40% for controls. In the present study we replicated the finding of Binetti et al.; however, the differential distribution of animal names by subcategory for the patients and controls could be accounted for by differences in the overall output and by assuming that word generation was strictly determined by prototypicality of the animal names. Thus, the increased proportion of farm animal names produced by patients with AD can be accounted for simply by postulating impaired access to semantic memory rather than degraded representations, the idea favored by Binetti et al.     

Monitoring the Changing Status of Semantic Memory in Alzheimer's Disease: An Evaluation of Several Process Measures

The deficits in generating correct words on verbal fluency tasks exhibited by patients with Alzheimer's disease (AD) are accompanied by fewer switching responses, smaller phonemic and semantic cluster sizes, and greater than normal percentages of errors and category labels. On category fluency tasks, patients generate a greater proportion of words that are prototypical of their semantic class. To determine whether any of these supplementary measures of verbal fluency performance might be useful in revealing processes involved in the decline of semantic memory in AD, we studied 219 patients with AD and 115 elderly control participants longitudinally. Previously reported group differences between patients and controls were replicated, but changes in average cluster size, error rates, and prototypicality were not related to changes in overall severity of dementia and test-retest stability was only modest. The change in the percentage of labels generated on the Supermarket task was related to changes in dementia severity, but test-retest stability on this measure was quite low. All of these process measures appear to reflect only the current status of the patient's attention to the task and access to semantic knowledge, but they do not forecast future performance. The numbers of switching responses on the fluency tasks were sensitive to differences between clinically deteriorated and clinically stable patients and showed fairly high test-retest stability. However, the number of switching responses is so highly correlated with the number of correct words that it contributes little to the understanding of the processes involved in the progressive decline in performance on fluency tasks by patients with AD.     

The relevance of the first two eye fixations for recognition memory processes

ABSTRACT

Stimuli can be recognised based on information from only one or two eye fixations. With only one fixation, item recognition is typically above chance level and performance generally saturates by the second fixation. Thus, the first two eye fixations play an important role for recognition memory performance. However, little is known about the involved processes. Therefore, two experiments were conducted to investigate hypotheses regarding the role of the first two eye fixations for specific recognition memory processes, that is, familiarity and recollection. In addition, we looked in detail at the unique contributions of (a) longer input duration and (b) additional information provided by a second fixation for familiarity- and recollection-based recognition, using a gaze-contingent stimulus presentation technique. The experiments showed that recollection- but not familiarity-based recognition increased with two compared to only one fixation, and that the second fixation boosted recollection both due to longer availability of the input and additional stimulus information gathered.     

Preschool children's proto-episodic memory assessed by deferred imitation

In two experiments, both employing deferred imitation, we studied the developmental origins of episodic memory in two- to three-year-old children by adopting a “minimalist” view of episodic memory based on its What–When–Where (“WWW”: spatiotemporal plus semantic) content. We argued that the temporal element within spatiotemporal should be the order/simultaneity of the event elements, but that it is not clear whether the spatial content should be egocentric or allocentric. We also argued that episodic recollection should be configural (tending towards all-or-nothing recall of the WWW elements). Our first deferred imitation experiment, using a two-dimensional (2D) display, produced superior-to-chance performance after 2.5 years but no evidence of configural memory. Moreover, performance did not differ from that on a What–What–What control task. Our second deferred imitation study required the children to reproduce actions on an object in a room, thereby affording layout-based spatial cues. In this case, not only was there superior-to-chance performance after 2.5 years but memory was also configural at both ages. We discuss the importance of allocentric spatial cues in episodic recall in early proto-episodic memory and reflect on the possible role of hippocampal development in this process.