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81.
Prefrontal cortex regulates inhibition and excitation in distributed neural networks. 总被引:9,自引:0,他引:9
Prefrontal cortex provides both inhibitory and excitatory input to distributed neural circuits required to support performance in diverse tasks. Neurological patients with prefrontal damage are impaired in their ability to inhibit task-irrelevant information during behavioral tasks requiring performance over a delay. The observed enhancements of primary auditory and somatosensory cortical responses to task-irrelevant distractors suggest that prefrontal damage disrupts inhibitory modulation of inputs to primary sensory cortex, perhaps through abnormalities in a prefrontal-thalamic sensory gating system. Failure to suppress irrelevant sensory information results in increased neural noise, contributing to the deficits in decision making routinely observed in these patients. In addition to a critical role in inhibitory control of sensory flow to primary cortical regions, and tertiary prefrontal cortex also exerts excitatory input to activity in multiple sub-regions of secondary association cortex. Unilateral prefrontal damage results in multi-modal decreases in neural activity in posterior association cortex in the hemisphere ipsilateral to damage. This excitatory modulation is necessary to sustain neural activity during working memory. Thus, prefrontal cortex is able to sculpt behavior through parallel inhibitory and excitatory regulation of neural activity in distributed neural networks. 相似文献
82.
83.
We introduce two simple empirical approximate Bayes estimators (EABEs)—
and
—for estimating domain scores under binomial and hypergeometric distributions, respectively. Both EABEs (derived from corresponding marginal distributions of observed test scorex without relying on knowledge of prior domain score distributions) have been proven to hold -asymptotic optimality in Robbins' sense of convergence in mean. We found that, where
and
are the monotonized versions of
and
under Van Houwelingen's monotonization method, respectively, the convergence rate of the overall expected loss of Bayes risk in either
or
depends on test length, sample size, and ratio of test length to size of domain items. In terms of conditional Bayes risk,
and
outperform their maximum likelihood counterparts over the middle range of domain scales. In terms of mean-squared error, we also found that: (a) given a unimodal prior distribution of domain scores,
performs better than both
and a linear EBE of the beta-binomial model when domain item size is small or when test items reflect a high degree of heterogeneity; (b)
performs as well as
when prior distribution is bimodal and test items are homogeneous; and (c) the linear EBE is extremely robust when a large pool of homogeneous items plus a unimodal prior distribution exists.The authors are indebted to both anonymous reviewers, especially Reviewer 2, and the Editor for their invaluable comments and suggestions. Thanks are also due to Yuan-Chin Chang and Chin-Fu Hsiao for their help with our simulation and programming work. 相似文献
84.
85.
86.
This study examined the effect of ambiguity intolerance on attitudes toward corporate diversity programs. It was found that, holding constant demographic backgrounds of age, gender, work experience, managerial position, and majority-minority status, ambiguity intolerance was negatively related to support for diversity programs. The study also replicated previous findings that women and racial minority members support diversity programs more than do men and racial majority members. This study demonstrates the importance of including personality variables in diversity research. 相似文献
87.
88.
内源性注意与外源性注意对数字加工的不同影响 总被引:5,自引:0,他引:5
分别采用内源性注意和外源性注意实验范式,材料为小数(1-4)和大数(6-9)的中文与阿拉伯数字,任务为判断数字是否大于5,考察在注意与非注意条件下不同大小数字加工的距离效应和符号效应。结果发现:⑴在内源性线索和外源性线索的注意条件下,大小数都出现了距离效应;但在非注意条件下,内源性线索时的大小数都出现了距离效应,而外源性线索时只有小数出现了距离效应,大数的距离效应明显减弱或消失。⑵在内源性线索和外源性线索的注意条件下,大小数都没有出现符号效应;但在非注意条件下,大数没有出现符号效应,而小数出现了符号效应(阿拉伯数字的绩效比中文数字差),并且内源性线索时的符号效应强度小于外源性线索。 相似文献
89.
90.
不同注意条件下的空间-数字反应编码联合效应 总被引:9,自引:0,他引:9
考察在无线索、内源性线索与外源性线索时不同符号数字在注意与非注意条件下的空间-数字的反应编码联合效应(Spatial Numerical Association of Response Codes,简称SNARC效应)。采用1到9的中文与阿拉伯数字为材料,以判断数字奇偶为任务。实验结果表明:⑴无线索时注意条件下阿拉伯和中文数字都出现了SNARC效应,而非注意条件下则都没有出现,并且受影响的主要是较大的数字(8、9);⑵外源性线索和内源性线索时,我们得到一个逐渐递减的SNARC效应,受影响的也主要是较大的数字(8、9)。在内源性线索的注意条件阿拉伯和中文数都有SNARC效应,而在非注意条件只有阿拉伯数有SNARC效应;在外源性线索的注意条件只有阿拉伯数有SNARC效应,而在非注意条件阿拉伯和中文都没有SNARC效应,说明外源性注意的影响比内源性注意更大,中文数字所受的影响比阿拉伯数字更大。 相似文献