GSK-3β activity in the hippocampus is required for memory retrieval

Several molecules were recently found to be important for the memory retrieval process in the hippocampus; however, the mechanisms underlying the memory retrieval remain poorly understood. GSK-3β has been implicated in the control of synaptic plasticity and memory formation. Here, we investigated the relationship between hippocampal GSK-3β activity and memory retrieval using behavioral and Western blotting methods. We found that GSK-3β was activated in the hippocampus after a retention session in the passive avoidance task. An intrahippocampal injection of the GSK-3β inhibitor, SB 216763, before the retention session blocked memory retrieval (but not reconsolidation) without affecting locomotor activity. These results suggest that GSK-3β activation would be essential for memory retrieval in the hippocampus.     

Roles of nucleus accumbens and basolateral amygdala in autoshaped lever pressing

Initially-neutral cues paired with rewards are thought to acquire motivational significance, as if the incentive motivational value of the reward is transferred to the cue. Such cues may serve as secondary reinforcers to establish new learning, modulate the performance of instrumental action (Pavlovian-instrumental transfer, PIT), and be the targets of approach and other cue-directed behaviors. Here we examined the effects of lesions of the ventral striatal nucleus accumbens (ACb) and the basolateral amygdala (BLA) on the acquisition of discriminative autoshaped lever-pressing in rats. Insertion of one lever into the experimental chamber was reinforced by sucrose delivery, but insertion of another lever was not reinforced. Although sucrose was delivered independently of the rats' behavior, sham-lesioned rats rapidly came to press the reinforced but not the nonreinforced lever. Bilateral ACb lesions impaired the initial acquisition of sign-tracking but not its terminal levels. In contrast, BLA lesions produced substantial deficits in terminal levels of sign-tracking. Furthermore, whereas ACb lesions primarily affected the probability of lever press responses, BLA lesions mostly affected the rate of responding once it occurred. Finally, disconnection lesions that disrupted communication between ACb and BLA produced both sets of deficits. We suggest that ACb is important for initial acquisition of consummatory-like responses that incorporate hedonic aspects of the reward, while BLA serves to enhance such incentive salience once it is acquired.     

Automatic attention towards face or body as a function of mating motivation

Because women?s faces and bodies carry different cues of reproductive value, men may attend to different perceptual cues as functions of their long-term versus short-term mating motivations. We tested this hypothesis in three experiments on 135 male and 132 female participants. When influenced by short-term rather than long-term mating motivations, men?s attention was captured by (Study 1), was shifted to (Study 2), and was distracted by (Study 3) the waist/hip area rather than the face on photographs of attractive women. Similar effects were not found among the female participants in response to photographs of attractive men. These results support the evolutionary view that, similar to the attentional selectivity found in other domains of life, male perceptual attention has evolved to selectively capture and hold reproductive information about the opposite sex as a function of short-term versus long-term mating goals.     

朴素物理观和朴素心理观--进化心理学视角

人类在进化过程中解决生存与繁衍问题需要适应物理环境和社会环境。进化心理学认为人类适应物理环境与社会环境的心理机制分别称为朴素物理观和朴素心理观。文章首先阐述了朴素物理观和朴素心理观的有关内容,并指出两性差异的一个重要方面在于移情和系统化的不同组合,同时对其进化意义做了分析。     

早期道教仪式

本译文评述了蔡雾溪关于早期道教仪式的博士论文,认为这是近几年同类研究中一部透彻精深并富有创见的研究论著。     

广博·新颖·实用——读郭秀艳著《实验心理学》有感

郭秀艳著《实验心理学》于2004年由人民教育出版社出版。笔者认为该著作具有广博、新颖、实用的特色,是实验心理学中的一部力作,值得心理学专业的研究生仔细研读。     

Mutual interactions between speech and finger movements

Speech output and finger movements were recorded as right-handed males repeated a syllable while making cyclical finger movements in three experimental conditions: (2) maintaining constant amplitude in both response systems; (b) alternating speech amplitude while attempting to maintain constant finger movement amplitude; and (c) alternating finger movement amplitude while attempting to maintain constant speech amplitude. Observations showed that output of the two response systems was coupled (one syllable was uttered with each finger movement) and entrained in amplitude (the amplitude pattern of the response that the subject attempted to keep constant followed that of the concurrently-active amplitude-modulated response). These interactions were bidirectional and were present with both left-handed and right-handed finger movements. The interactions are more extensive and subtle than mere interference wtih one response system by the other, and apparently do not depend on anatomical overlap of the responding neural systems.     

Active memory processes in visual sentence comprehension: Clause effects and pronominal reference

Two experiments were conducted to investigate active memory processes during reading. Subjects read two-clause sentences one word at a time at a self-paced rate. Following each sentence a probe word was presented; subjects were to decide if this word occurred in the sentence they had just read. The first experiment examined clausal effects during reading. Reaction times to items from the final clause were shorter than those to items from a previous clause even when the same number of words intervened. The second experiment used the clause effect to address the issue of proniminal reference. Results indicated that a pronoun in the final clause activated the meaning of its antecedent, thus demonstrating that the method is sensitive to both surface and meaning codes in active memory.     

Differential effects of oral reading to improve comprehension with severe learning disabled and educable mentally handicapped students

The purpose of this study was to evaluate the effectiveness of oral reading as a teaching technique for improving reading comprehension of 11 Educable Mentally Handicapped or Severe Learning Disabled adolescents. Students were tested on their ability to answer comprehension questions from a short factual article. Comprehension improved following the oral reading for students with a reading grade equivalent of less than 5.5 (measured from the Wide Range Achievement Test) but not for those students having a grade equivalent of greater than 5.5. This association was statistically significant (p = less than .01). Oral reading appeared to improve comprehension among the poorer readers but not for readers with moderately high ability.     

Symbolic forms can be mnemonics for recall

Form symbolism using squares and circles can aid recall. In Experiment 1, subjects saw 20 words, each presented in a circle or a square. Words like SOFT and MOTHER were presented in circles in the “congruent” condition, whereas the same words were presented in squares in the “incongruent” condition. Two experiments revealed that words in the congruent condition were more likely to be recalled. A comparison of the conditions with a baseline condition, in which 20 listed words were not closely related to either of the shapes, suggests that the effect was more likely due to facilitation produced by the congruent condition than to inhibition from the incongruent condition.